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Preparation method for medlar flavone extracted from medlar crops

A technology of wolfberry flavonoids and wolfberry leaf flavones, which is applied in the field of natural product preparation technology, can solve the problems of no substantial progress in flavonoid medicinal research, achieve the effects of easy control of technical parameters, simplification of process, and reduction of equipment investment

Inactive Publication Date: 2016-12-07
成都薇诺娜生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, there has been no substantial progress in the medicinal research of flavonoids including citrin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The preparation method of wolfberry flavonoids extracted from wolfberry crops uses the bark of wolfberry plants and leaves of wolfberry as raw materials, and the flavonoids are prepared by combining techniques such as extraction, adsorption, elution, and concentration, which has low cost and high extraction efficiency. Features, especially adopt the following setting method: including the following steps:

[0043] 1) Remove the roots of wild wolfberry plants, leave the stems and leaves of wolfberry, peel the stems of wolfberry to obtain the skin of wolfberry, manually pick and remove impurities from the leaves of wolfberry, and dry them together with the skin of wolfberry in a room with natural ventilation and shade , to obtain the dry sample of Lycium barbarum leaf and the dry sample of Lycium barbarum bark;

[0044] 2) The dried wolfberry leaf sample is crushed and passed through a 80-280 mesh sieve to obtain wolfberry leaf powder;

[0045] 3) After crushing the dry sa...

Embodiment 2

[0050] This embodiment is further optimized on the basis of the above-mentioned embodiments. In order to better realize the present invention, the following setting method is adopted in particular: the step 4) includes the following specific steps:

[0051] 4-1) Leach wolfberry leaf powder and ethanol with a mass concentration of 40-97.50% at a volume ratio of 1:40-90 for 3-300 hours to obtain a leaf extract;

[0052] 4-2) After the leaf extract is ground by a colloid mill for 8-12 times, a colloidal Lycium barbarum leaf extract solution is obtained;

[0053] 4-3) Homogenize the colloidal Lycium barbarum leaf extraction solution under a pressure of 20-180Mpa, and then centrifuge to obtain leaf supernatant and leaf filter residue;

[0054] 4-4) Remove impurities from the leaf supernatant through a ceramic membrane with a pore size of 0.05-5 μm at a flow rate of 2-8 t / h at a temperature of 30-45°C and a pressure of 0.1-2Mpa to obtain leaf partial filtrate;

[0055] 4-5) After ...

Embodiment 3

[0058] This embodiment is further optimized on the basis of any of the above-mentioned embodiments. In order to better realize the present invention, the following setting method is adopted in particular: the step 5) includes the following specific steps:

[0059] 5-1) Extracting wolfberry skin powder and acetone with a mass concentration of 60-85% at a volume ratio of 1:50-80 for 30-280 hours to obtain a skin extract;

[0060] 5-2) After the skin extract is ground by a colloid mill for 6-12 times, a colloidal Lycium barbarum extract solution is obtained;

[0061] 5-3) homogenize the colloidal Lycium barbarum extract solution under a pressure of 20-180Mpa, and then centrifuge to obtain skin supernatant and skin filter residue;

[0062] 5-4) removing impurities from the skin supernatant through a ceramic membrane with a pore size of 0.05-5 μm at a flow rate of 2-8 t / h at a temperature of 25-45°C and a pressure of 0.4-1.2Mpa to obtain skin filtrate;

[0063] 5-5) After the ski...

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PUM

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Abstract

The invention discloses a preparation method for medlar flavone extracted medlar crops. The preparation method includes: removing roots of wild medlar plants, remaining medlar stems and medlar leaves, peeling the medlar stems to obtain medlar peels, subjecting the medlar leaves to manual picking and impurity removing to be dried in shade with the medlar peels through indoor natural ventilation to obtain medlar leaf powder and medlar peel powder; subjecting the medlar leaf powder and the medlar peel powder to preparation of medlar leaf flavone and medlar peel flavone by adopting digestion, adsorption, elution and concentration techniques to obtain a concentrated medlar leaf flavone solution and a concentrated medlar peel flavone solution; mixing and drying the concentrated medlar leaf flavone solution and the concentrated medlar peel flavone solution to obtain flavone powder. The medlar peels and the medlar leaves of the medlar plants are taken as raw materials, and the techniques of digestion, adsorption, elution, concentration and the like are combined in preparation of the flavone.

Description

technical field [0001] The invention relates to the technical field of natural product preparation technology, in particular to a preparation method for extracting wolfberry flavonoids from wolfberry crops. Background technique [0002] Lycium barbarum is people's general designation for species under the genus Lycium barbarum such as commercial wolfberry, plant Ningxia wolfberry, and Chinese wolfberry. People's daily edible and medicinal goji berries are mostly the fruit "Goji berries" of Ningxia goji berries, and Ningxia goji berries are the only species listed in the "2010 Edition of Chinese Pharmacopoeia". Four Treasures of Traditional Chinese Medicine. [0003] Flavonoids generally refer to a series of compounds in which two benzene rings (A- and B-rings) with phenolic hydroxyl groups are connected to each other through the central three carbon atoms, and the basic core is 2-phenylchromone. Functional groups such as phenolic hydroxyl group, methoxyl group, methyl grou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P9/00A61P9/10A61P35/00A61P39/06
CPCA61K36/815A61K2236/333A61K2236/53A61K2236/55
Inventor 车洪泽
Owner 成都薇诺娜生物科技有限公司