Method for preparing herb preparation for treating gout

A technology for herbs and preparations, applied in plant raw materials, plant/algae/fungus/moss ingredients, drug combinations, etc., can solve the problems of product safety risks, inability to kill bacterial spores, unstable product quality, etc., to avoid high temperature The effect of sterilizing the loss of active ingredients, ensuring the active ingredients of the product, and improving the use effect of the product

Inactive Publication Date: 2016-12-07
广西本草坊保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the technology of the present invention is not systematic, there are multiple dryings and the drying efficiency is low, and the low-temperature sterilization method used cannot kill bacterial spores, resulting in unstable product quality
Another example is that CNIO5663926A Chinese patent discloses a kind of uric acid-lowering plant enzyme and preparation method thereof: raw materials include fuzhuan black tea, green brick black tea, kombucha bacterial classification, pitaya red pulp, ripe papaya pulp, green papaya pulp, Grape fruit, psyllium seed gum, Zhugai kernel, Tuhuopu, Achyranthes bidentata, grass sage, Shiyingpu, cat's whiskers, peach blossom, peony bark, red peony root, angelica tail, silver flower vine, grape root, Guan The uric acid-lowering plant enzymes are produced by processing, fermenting, and ultra-high pressure sterilization of fragrant leaves. This method has a high operating pressure of up to 350MPa, high energy consumption, and complex components.
Fermentation prepares yeast to reproduce a large number of bacteria, and adopts ultra-high pressure and low temperature sterilization. This method has basically no effect on spore-bearing bacteria, so product safety has certain risks.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] An example of the method for preparing herbal preparations for the treatment of gout according to the present invention, comprising the steps of:

[0048] (1) Proportioning: the proportioning of medicinal and edible raw materials by mass percentage is 10% of cloves, 8% of licorice, 6% of Chinese yam, 10% of poria cocos, 8% of medlar, 16% of hemp seed, 25% of purslane, Seabuckthorn 10%, Cassia 7%;

[0049] (2) Pulverization: the raw material is first pulverized to 10um with a micro-powder pulverizer, and then pulverized to 50nm with a nano pulverizer;

[0050] (3) Slurry mixing: after nano-grinding, add pure water to the nano-powder at a ratio of 1:1.05, stir evenly, and measure the solid content at 48%;

[0051] (4) Enzymolysis: adding 1.2% ligninase and 2% cellulase by mass percentage. The reaction control conditions are reaction temperature: 40°C, pH=5.5, stirring speed=50r / min, reaction time=48h;

[0052] (5) Sterilization: ozone concentration is 0.1mg / L, steriliz...

Embodiment 2

[0059] Another example of the method for preparing solid fructo-oligosaccharide of the present invention, comprises the steps:

[0060] (1) Proportioning: the raw materials of the same medicine and food are proportioned by mass percentage as clove 15%, licorice 5%, yam 10%, poria cocos 14%, medlar 6%, hemp seed 10%, purslane 20%, Sea buckthorn 10%, cassia seed 10%;

[0061] (2) Pulverization: the prepared raw materials are first pulverized to 50um with a micro-powder pulverizer, and then pulverized to 200nm with a nano pulverizer;

[0062] (3) Slurry mixing: after nano-grinding, add purified water to the nano-powder at a ratio of 1:1.15, stir evenly, and measure the solid content at 45%;

[0063] (4) Enzymolysis: adding 1.8% ligninase by mass percentage and 2-2.5% cellulase by mass percentage. The reaction control conditions are reaction temperature: 45°C, pH=6.5, stirring speed=60r / min, reaction time=36h;

[0064] (5) sterilization: ozone sterilization, ozone concentration...

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PUM

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Abstract

A method for preparing a herb preparation for treating gout includes the following steps that medicinal and edible raw materials including clove, licorice roots, Chinese yam, poria cocos, fructus lycii, fructus cannabis, herba portulacae, fructus hippophae and semen cassiae are weighed according to a proportion, ground to be 10-50 micrometers through a micro-grinder and then ground to be 50-200 nm through a nano-grinder, pure water is added to carry out paste conditioning till the solid content reaches 45-48%, ligninase and cellulase are added for a reaction for 36-48 h, ozone sterilization is carried out, fermentation is carried out to prepare ferment, drying is carried out, granulating is carried out to obtain 2-0.5 mm granules, packaging is carried out, and the herb preparation for treating gout is obtained. The preparation has the advantages that the preparation is obvious in effect, safe and convenient to take and free of side effects, and the preparing process is simple and environmentally friendly.

Description

technical field [0001] The invention relates to a method for preparing a herbal preparation for treating gout, in particular to a method for preparing the preparation by combining nano-pulverization technology and enzyme fermentation technology. Background technique [0002] Gout is a disorder of purine metabolism, also known as "hyperuricemia", which belongs to a type of arthritis, also known as metabolic arthritis. It is a group of diseases caused by long-term purine metabolism disorder and increased blood uric acid that cause tissue damage. Gout is a metabolic disease caused by purine metabolism disorder, but its incidence has obvious heterogeneity. In addition to hyperuricemia, it can be manifested as acute arthritis, tophi, chronic arthritis, joint deformity, chronic interstitial nephritis and uric acid Sexual urolithiasis. Clinically, it can be divided into two categories: primary and secondary. Primary gout is mostly caused by congenital purine metabolism abnormalit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P19/06
Inventor 曾梓强梁鹏
Owner 广西本草坊保健品有限公司
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