Microfluidic module for large-scale preparation of liquid drops

Abstract

The invention relates to a microfluidic module for large-scale preparation of liquid drops. A multi-stage modular amplification strategy is adopted; the module design comprises two parallel and stacked amplification processes; a plurality of modules operate in an integrated manner to realize an industrial production demand; N is the number of parallel channels in each chip group; M is the number of stacked chips of each module; the whole module comprises N * M channels; if Q is the number of integrated modules, the total yield is P= eta x (N * M * Q), and is respectively in positive correlation with N, M and Q; eta is the yield of the single channel. In actual application, three parameters can be reasonably weighed according to the demand for space utilization and yield, feature parameters of an obtained product and the like so as to achieve the optimal effect. The application of the microfluidic module for the large-scale preparation of the liquid drops or a microfluidic system based on the module realizes the large-scale production of the liquid drops or emulsion; when serving as a template, the microfluidic module can synthesize a functional particle material; the microfluidic module is widely applied to the field of biological medicines, chemistry and chemical engineering, material preparation and the like.

Description

technical field [0001] The patent of the present invention relates to a microfluidic module for large-scale preparation of droplets. The prepared droplets can be used as templates to prepare emulsion products or granular products on a large scale, which belongs to the field of industrial application of microfluidic technology. Background technique [0002] In recent years, the microfluidic technology developed in the fields of biomedicine and chemical engineering has significant advantages in the preparation of single-weight droplets and complex droplets, and can achieve precise control of the number and size of each droplet. Using the prepared droplets as a template, granular products or emulsion products can be synthesized. Based on this microfluidic method, relevant researchers have prepared highly monodisperse granular material products with different shapes, diverse structures, and complex components, and achieved precise regulation, and achieved a series of remarkable ...

AI Technical Summary

Problems solved by technology

However, this flux is still difficult to meet the actual demand of the industry; these devices are often only used in parallel in two-dimensional space, and rarely consider multi-level amplification in multiple dimensions; at the same time, looking at the representative research results, Most of the chip materials are made of silicon glass (deep ion reactive etching) and PDMS (photoetching technology), the chip production is complicated, the cycle is long, and the cost is high

In addition, the minimum channel size of these chips is around tens of microns, which is extremely easy to clog and unreliable in operation, making it difficult to apply to high-viscosity fluid applications in industry

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