Implanted completely bioresorbable blood vessel polymer support

A polymer and implantable technology, applied in the field of medical devices, can solve problems such as insufficient segmental support and stability, inability to perfectly unify technical indicators, and affect the risk of thrombosis in the stent, achieving strong passing ability and operability, Reduction of restenosis rate and good effect of endothelialization

Pending Publication Date: 2016-12-21
SHENZHEN SALUBRIS BIOMEDICAL ENG CO LTD
View PDF4 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this solution also has relatively large deficiencies in setting smaller crimping diameters, and especially in the support and stability of its sections when used in polymer stents
[0012] In addition, the tube wall thickness of the existing degradable stent is affected by the material and processing methods, which are thicker than the metal stent, which is 2 times or more than the metal stent, which incre...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Implanted completely bioresorbable blood vessel polymer support
  • Implanted completely bioresorbable blood vessel polymer support
  • Implanted completely bioresorbable blood vessel polymer support

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1 An implantable fully bioabsorbable vascular polymer stent

[0059] See attached figure 1 , 2 As shown in 3A-3G, an implantable fully bioabsorbable vascular polymer stent, made of polylactic acid, includes more than five ring-shaped corrugated support rods 1, and connecting rods 2 connected to the support rod 1 at intervals, The support rod 1 of the bracket is formed by alternately connecting "Ω"-shaped waves 3 and "m"-shaped waves 4, and the connection between two adjacent support rods is formed by connecting rods 2 in the "Ω"-shaped wave The top is connected with the "m"-like wave bottom.

[0060] The class "m" shaped wave 4, such as image 3 As shown in A, and "Ω" shaped wave 3, such as image 3 As shown in B, it is composed of two groups of positive "s" and inverted "s" connections, respectively as figure 2 shown.

[0061] The connecting rods between the two adjacent supporting rods are all straight rods.

[0062] This implantable fully bioabsorb...

Embodiment 2

[0063] Embodiment 2 An implantable fully bioabsorbable vascular polymer stent

[0064] See attached figure 1 , 2As shown in 3A-3G, an implantable fully bioabsorbable vascular polymer stent includes five or more ring-shaped corrugated support rods 1, and connecting rods 2 connected to the support rod 1 at intervals, and the embodiment 1 The difference is that in this specific embodiment, the widths of the support rods and the connecting rods are different, the width of the support rods at both ends of the bracket is the thickest, and the width of the connecting rods at the two ends of the bracket is next, Then to the width of the remaining support rods, the width of the remaining connecting rods is the thinnest. Among them, the angle between the positive "s" and inverted "s" connecting segments is 5-10 degrees.

Embodiment 3

[0065] Example 3 An implantable fully bioabsorbable vascular polymer stent

[0066] See attached figure 1 , 2 As shown in 3A-3G, an implantable fully bioabsorbable vascular polymer stent includes five or more ring-shaped corrugated support rods 1, and connecting rods 2 connected to the support rod 1 at intervals, and the embodiment 1 The difference is that in this specific embodiment, the widths of the support rods and the connecting rods are different, the width of the support rods at both ends of the bracket is the thickest, and the width of the connecting rods at the two ends of the bracket is next, Then to the width of the remaining support rods, the width of the remaining connecting rods is the thinnest. Among them, the angle between the positive "s" and inverted "s" connecting segments is 40-45 degrees.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Angleaaaaaaaaaa
Angleaaaaaaaaaa
Angleaaaaaaaaaa
Login to view more

Abstract

The invention relates to an implanted completely bioresorbable blood vessel polymer support which comprises five or more annular wave-shaped supporting rods and connecting rods connected between the supporting rods at intervals. The supporting rods of the support are formed by alternately connecting quasi-arc-shaped waves and quasi-m-shaped waves, wherein the quasi-arc-shaped waves and the quasi-m-shaped waves are formed by connecting two sets of forward s and inverted s respectively, and every two adjacent supporting rods are connected by connecting the tops of the quasi-arc-shaped waves and the bottoms of the quasi-m-shaped waves through the corresponding connecting rod. The net pattern form of the polymer support is carved on a thin wall pipe through lasers. According to the scheme, the contradiction among the radial supporting force, the wall thickness and flexibility of the polymer support is resolved, the radial supporting force, the wall thickness and flexibility are considered at the same time, good passage capacity is achieved, enough mechanical supporting can be given to a lesion segment within the specific time of injury healing, the support is gradually absorbed by the body after injury healing, endothelialization is good, and the stenosis rate of the support and the risk of the support in later stent thrombosis are reduced effectively.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to an implantable fully bioabsorbable blood vessel polymer stent. Background technique [0002] Since the first metal stent Palmaz-Schatz was implanted into the human body in 1985, stent interventional therapy has successfully solved the problem of high restenosis rate in the era of simple balloon dilatation, and has become the main method of clinical treatment. After the metal stent is implanted in the human body, it is found that the restenosis rate in the stent is still as high as about 20% due to inflammatory reactions, neointimal hyperplasia, negative vascular remodeling, and delayed endothelialization of the stent. [0003] In order to solve this problem, the first generation of polymer-coated drug-eluting stents came into being. The emergence of drug-eluting stents will reduce the restenosis after interventional treatment from 30-40% in the era of simple PTCA to 15-25% in the ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61F2/915A61M31/00A61L31/06A61L31/10A61L31/14A61L31/16
CPCA61L31/06A61L31/10A61L31/14A61L31/16A61M31/00A61F2/915A61F2002/91575A61F2230/0045A61L2300/416A61M2210/12
Inventor 陈泳胡晓露高康荣申峰
Owner SHENZHEN SALUBRIS BIOMEDICAL ENG CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products