Plant essence itching-relieving mosquito-repellent liquid and manufacturing method thereof

A technology of plant essence and production method, applied in skin care preparations, drug combinations, pharmaceutical formulas, etc., can solve the problems of short repellent time and unsafe use of non-natural components

Inactive Publication Date: 2017-03-22
东莞小猕猴户外用品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing technology has the problems of unsafe use o

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The production method of plant essence itching and mosquito repellent is made by the following steps:

[0020] Get 7 parts by weight of clove oil, 8 parts by weight of lemon eucalyptus oil and add in the ethanolic aqueous solution of 40 weight parts to obtain the first solution, and described ethanolic water solution is 70% ethanolic water solution (v / v); Described lemon eucalyptus oil, clove oil can be Obtained by using the existing extraction technology, optionally, the lemon eucalyptus oil is the volatile oil obtained by distilling lemon eucalyptus leaves by steam distillation, and the clove oil is the volatile oil obtained by steam distillation distillation of clove leaves. Before distillation The lemon eucalyptus leaves and clove leaves are crushed and preferably passed through a five-mesh sieve.

[0021] Take 10 parts by weight of Cnidium, 10 parts by weight of Kochia, 15 parts by weight of Artemisia argyi, the water content of described Cnidium, Kochia kohlrabi i...

Embodiment 2

[0024] A plant essence antipruritic mosquito repellent liquid is prepared by any one of the aforementioned methods for making plant essence antipruritic mosquito repellent liquid.

Embodiment 3

[0026] Acute oral toxicity test in rats.

[0027] Test sample: 6g of plant essence antipruritic mosquito repellent liquid in Example 1 was added to 12mL of water and mixed well, and used as a test sample.

[0028] Experimental animals: Wistar rats with a body weight of 160-200 g, 3 males and 3 males, and 6 rats in total were selected that had been adapted for more than 2 days in the laboratory and had no abnormal health status.

[0029] Test method: Animals were fasted overnight, and 2ml per animal was orally administered orally, and the symptoms after intragastric administration were observed and recorded, and the median lethal dose (LD50) was calculated for two weeks of continuous observation.

[0030] Experimental results: no obvious poisoning symptoms, no death. The median lethal dose was not measured, or the acute oral median lethal dose for males and females was greater than 5000 mg / kg.

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PUM

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Abstract

The invention provides plant essence itching-relieving mosquito-repellent liquid and a manufacturing method thereof. The method includes steps: adding, by weight, 5-10 parts of clove oil and 5-10 parts of eucalyptus citriodora oil into 30-50 parts of ethanol water solution to obtain first solution; adding, by weight, 10-15 parts of fructus cnidii, 10-15 parts of fructus kochiae and 10-20 parts of folium artemisiae argyi into 120 parts of ethanol water solution, and performing reflux extraction for 3-4h at a constant temperature of 30-40 DEG C and under a pressure of 0.1-0.13MPa to obtain second solution; concentrating the second solution to 40-50 parts by weight, and mixing with the first solution; adding a ph value regulator to regulate a ph value to 6.5. The plant essence itching-relieving mosquito-repellent liquid has functions of itching relieving and mosquito repelling.

Description

technical field [0001] The invention belongs to the technical field of outdoor products, and in particular relates to a preparation method of an outdoor plant essence antipruritic mosquito repellent liquid and a plant essence antipruritic mosquito repellent liquid. Background technique [0002] Mosquitoes can not only bring people annoying itching, it may also evolve into difficult scars if not handled properly, which will lastingly affect the appearance of people's skin, and the main harm of mosquitoes is to spread diseases. According to relevant studies, there are more than 80 kinds of diseases transmitted by mosquitoes. [0003] One solution is to prevent mosquitoes from contacting human skin by isolating them. In the prior art, there are problems that the use of non-natural components is unreliable and the mosquito repellent time is short. [0004] When carrying out outdoor activities, carry things as small as possible and as light as possible. SUMMARY OF THE INVENTI...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/92A61Q17/02A61P17/04
CPCA61K8/97A61K8/922A61Q17/02
Inventor 万小耀
Owner 东莞小猕猴户外用品有限公司
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