Vaginal gel and preparation method thereof

A technology of vaginal gel and transparent xanthan gum, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve side effects, high cost, slow effect of traditional Chinese medicine and cannot be relieved in time Symptoms and other problems, to achieve the effect of improving vaginal moisture and promoting repair

Active Publication Date: 2017-04-26
浙江因诺泰医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently, the treatment products for vaginitis or vaginal dryness are divided into three categories: 1. Western medicines, such as metronidazole, chlorhexidine, miconazole and ketoconazole, etc., are bactericidal and antibacterial. Western medicines have quick effects but are prone to drug resistance and There are side effects; 2. Traditional Chinese medicine, such as cnidium fruit, flavescens, Phellodendron cortex, alum, licorice, borneol and Kochia scoparia, etc., have the functions of clearing away heat and detoxification, killing insects and relieving itching, and the simple use of traditional Chinese medicine is slow to take effect

Method used

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Embodiment 1

[0022] A kind of vaginal gel described in this embodiment and preparation method thereof, comprises each component of following mass concentration:

[0023] 1. Macromolecular sodium hyaluronate: 0.2%

[0024] 2. VES-HA: 0.5%

[0025] 3. EGF: 0.001%

[0026] 4. Vitamin C: 0.003%

[0027] 5. Calcium chloride: 0.01%

[0028] 6. Pentylene glycol: 2%

[0029] 7. Glycerin: 10%

[0030] 8. Transparent xanthan gum: 1%

[0031] The molecular weight of the macromolecule sodium hyaluronate is between 400,000 and 1,000,000 Daltons.

[0032] During preparation, add sodium hyaluronate, vitamin E succinate-modified hyaluronic acid, EGF, vitamin C and calcium chloride into deionized water with a total water content of about 98%, and mix until dissolved; Add pentylene glycol, glycerin and transparent xanthan gum and mix until dissolved to obtain a uniform system; add ionized water, stir well, and finally adjust the pH of the mixture gel to 4.5±0.5 with disodium hydrogen phosphate-citric...

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PUM

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Abstract

The invention relates to the technical field of preparation of colpitis medicines, and especially relates to a vaginal gel and a preparation method thereof in order to solve the technical problem of unsatisfactory bacteriostasis, lubrication and moisture retention effects of existing vaginal gel products. The vaginal gel mainly comprises sodium hyaluronate, vitamin E succinate modified hyaluronic acid, EGF (epidermal growth factors), vitamins C, calcium chloride, pentanediol, glycerin, Rhodicare and a buffer system adopting disodium hydrogen phosphate-citric acid as gel. The vaginal gel has anti-inflammatory activity, improves the wetness of vaginas, is used for treating vaginal inflammatory diseases and alleviating vaginal dryness or used as a human body lubricant, has a vaginal mucosa squamous cell layer restoration promoting effect, can improve vaginal mucosa layer thinning and restore small injuries in vaginas to recover the elasticity and the softness of the vaginal mucosa, and is suitable for colpitis and vagina dryness people.

Description

technical field [0001] The invention relates to the technical field of vaginitis medicine preparation, in particular to a vaginal gel and a preparation method thereof. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women, including bacterial vaginosis, fungal vaginitis and trichomonas vaginitis. The clinical symptoms of vaginitis are mainly manifested as increased vaginal discharge with peculiar smell, genital itching, and causing cervical and uterine infection and pelvic inflammatory disease. The main population of vaginal dryness or atrophic vaginitis is postmenopausal women. According to survey statistics, about half of postmenopausal women have vaginal dryness. The vaginal mucosa is composed of glycogen-rich nonkeratinized stratified squamous epithelium and a fibrous basement membrane. During the reproductive period, the stratified squamous epithelium is rich in glycogen, and the vaginal mucosa is moist and elastic. After menop...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K38/18A61K31/728A61K47/36A61K47/24A61P15/02
CPCA61K9/0034A61K9/06A61K31/375A61K31/728A61K38/1808A61K47/24A61K47/36A61K2300/00
Inventor 杨维徐丽君蔡建光童振飞
Owner 浙江因诺泰医疗器械有限公司
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