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Compound traditional Chinese medicine composition capable of regulating blood fat and purpose thereof

A technology for regulating blood lipid and composition, applied in the field of medicine, can solve problems such as adverse reactions, and achieve the effects of low price, significant blood lipid regulating effect and high cost performance

Inactive Publication Date: 2017-04-26
HARBIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most of the blood lipid-regulating drugs commonly used in clinical practice are chemically synthesized preparations, which need to be taken for a long time, such as statins, fibrates, ezetimibe, bile acid chelating agents, and niacin, etc., but they all have serious adverse reactions

Method used

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  • Compound traditional Chinese medicine composition capable of regulating blood fat and purpose thereof
  • Compound traditional Chinese medicine composition capable of regulating blood fat and purpose thereof
  • Compound traditional Chinese medicine composition capable of regulating blood fat and purpose thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1 A kind of preparation method of the Chinese medicine composition of compound recipe regulating blood fat

[0029] Cassia seed extract 6kg, Poria cocos powder 3kg, cucumber seed powder 1kg

[0030] Wherein the extraction steps of Semen Cassiae extract are as follows:

[0031] (1) Heating and reflux extraction for the first time: depending on the dried medicinal material of Semen Cassiae, add 70 kg of ethanol aqueous solution with a concentration of 50% by volume, heat and reflux after soaking for 12 hours, start timing after the solution boils, and keep a slight boiling state for reflux extraction for 2 hours, Filter and collect to obtain the ethanol extraction solution for the first time;

[0032] (2) Heating and reflux extraction for the second time: adding 70kg volume percent concentration to the filter residue after extracting and filtering for the first time is 50% ethanol aqueous solution to carry out the second heating and reflux, start timing after ...

Embodiment 2

[0035] Embodiment 2 A kind of preparation method of the Chinese medicine composition of compound recipe regulating blood fat

[0036] Cassia seed extract 5kg, Poria cocos powder 5kg, cucumber seed powder 1.5kg

[0037] Wherein the extraction steps of Semen Cassiae extract are as follows:

[0038] (1) Heating and reflux extraction for the first time: depending on the dried medicinal material of Semen Cassiae, add 92 kg of ethanol aqueous solution with a concentration of 50% by volume, heat and reflux after soaking for 12 hours, start timing after the solution boils, and keep a slight boiling state for reflux extraction for 2 hours, Filter and collect to obtain the ethanol extraction solution for the first time;

[0039] (2) Heating and reflux extraction for the second time: adding 92kg volume percent concentration to the filter residue after the first extraction and filtration is 50% ethanol aqueous solution for the second heating and reflux, start timing after the solution bo...

Embodiment 3

[0041] Embodiment 3 A kind of preparation method of the Chinese medicine composition of compound recipe regulating blood fat

[0042] Cassia seed extract 8kg, Poria cocos powder 2kg, cucumber seed powder 1kg

[0043] Wherein the extraction steps of Semen Cassiae extract are as follows:

[0044](1) Heating and reflux extraction for the first time: depending on the dried medicinal material of Semen Cassiae, add 55 kg of ethanol aqueous solution with a concentration of 50% by volume, heat and reflux after soaking for 12 hours, start timing after the solution boils, and keep a slight boiling state for reflux extraction for 2 hours, Filter and collect to obtain the ethanol extraction solution for the first time;

[0045] (2) Heating and reflux extraction for the second time: adding 66kg of volume percentage concentration to the filter residue after extraction and filtration for the first time is that 50% ethanol aqueous solution is heated and refluxed for the second time, start ti...

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Abstract

The invention discloses a compound traditional Chinese medicine composition capable of regulating blood fat and a purpose thereof, which belong to the technical field of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following raw materials by weight percentage: 40-80% of a cassia seed extract product, 10-50% of Poria cocos powder, and 5-15% of cucumber-seed powder. The cassia seed extract product is prepared by the process that a cassia seed drying medicinal material is subjected to heating reflux extraction with an ethanol aqueous solution with the volume percentage concentration of 50%, and vacuum concentration. Through pharmacological experiment on experiment hybrid hyperlipidemia rats, the compound traditional Chinese medicine composition has the advantages of obvious fat regulation, good security, simple and convenient medication, low cost, and convenient transport and preservation, and the traditional Chinese medicine composition as a blood fat-adjusting medicine has wide application prospect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound traditional Chinese medicine composition for regulating blood lipid and its application. Background technique [0002] With the improvement of living standards, people's dietary factors, namely high cholesterol and high saturated fatty acid intake, have increased sharply, while the amount of exercise has decreased significantly, and the incidence of hyperlipidemia has increased year by year. Hyperlipidemia refers to excessive blood lipid levels, such as the increase of total cholesterol (TC) and triglyceride (TG) and low-density lipoprotein (LDL-C) in serum, and the increase of high-density lipoprotein (HDL-C) ) can directly cause some diseases that seriously endanger human health, such as atherosclerosis and coronary heart disease. Hyperlipidemia can also lead to fatty liver, cirrhosis, cholelithiasis, pancreatitis, peripheral vascular disease, hyperuric...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/482A61P3/06
CPCA61K36/482A61K36/076A61K36/42A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 杨宝峰杜智敏张妍李欣张勇
Owner HARBIN MEDICAL UNIVERSITY
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