Kudzuvine root composition with liver protection effect and preparation method thereof

Abstract

The invention provides a kudzuvine root composition with a liver protection effect and a preparation method thereof. The kudzuvine root composition is prepared from the following main raw materials in parts by weight: 5 to 10 parts of kudzuvine root, 5 to 10 parts of dried lily bulb, 5 to 8 parts of radix ophiopogonis, 5 to 8 parts of turtle shell, 5 to 8 parts of Chinese magnoliavine fruit, 3 to 5 parts of licorice root, 3 to 5 parts of spreading hedyotis herb, 8 to 10 parts of herba andrographitis, 2 to 3 parts of szechwan Chinaberry fruit and 8 to 10 parts of radix aucklandiae. The preparation method comprises the following steps: taking the kudzuvine root, the dried lily bulb, the radix ophiopogonis, the turtle shell, the Chinese magnoliavine fruit, the licorice root, the spreading hedyotis herb, the herba andrographitis, the szechwan Chinaberry fruit and the radix aucklandiae; adding 10 to 15 times by weight of ethanol with the mass concentration of 60 to 80 percent; performing refluxing extraction twice, wherein 1 hour is consumed each time; combining extracting solutions; concentrating until thick paste with relative density of 1.30 to 1.38 at 60 DEG C is formed; adding a proper amount of microcrystalline cellulose, starch and magnesium stearate to prepare tablets. The kudzuvine root composition has the effects of improving liver functions and reducing transaminase.

Description

technical field [0001] The invention belongs to medical preparations, in particular to a kudzu root composition with liver-protecting effect and a preparation method thereof. Background technique [0002] Chronic hepatitis B is a common and frequently-occurring disease in my country, which endangers the health of people of all ages. During liver disease, liver function is damaged to varying degrees, liver detoxification, excretion function, reserve and regeneration ability are reduced, liver blood flow is reduced, and various enter Drugs in the liver aggravate the metabolic load, resulting in internal environment disturbance, which in turn causes liver damage. Long-term liver damage can lead to liver cirrhosis and even liver cancer. [0003] At present, interferon is commonly used clinically to treat chronic hepatitis B. Although it is widely used, the curative effect is more and more disappointing. At the same time, interferon has indications and obvious adverse reactions in...

AI Technical Summary

Problems solved by technology

[0003] At present, interferon is commonly used clinically to treat chronic hepatitis B. Although it is widely used, the curative effect is more and more disappointing. At the same time, interferon has indications and obvious adverse reactions in the treatment of hepatitis B, which is inconsistent with the characteristics of liver diseases in my country; another The commonly used drug lamivudine is favored by doctors and patients in the initial stage of its application because of its rapid virus suppression, high HBV DNA conversion rate, mild and less adverse reactions, and relatively low price. Prolonged, problems gradually emerged; such as inducing the mutation of hepatitis B virus, the reality of being happy before worrying, narrow indications, limited therapeutic effect, long-term treatment course, "rebound" after drug withdrawal, and may make the disease worse. Significantly worsened, or even worsened

[0004] my country is a country with a high incidence of hepatitis, and there are more than 200 million patients with various types of liver diseases. Most of them need drugs with liver protection effects. The research on liver injury in modern medicine is relatively in-depth. The mechanism of liver injury has been explored from many aspects, and the development of A variety of liver-protecting drugs have been developed, but the curative effect is still unsatisfactory; Chinese medicine has the characteristics of multi-target and multi-link comprehensive effects, and has unique advantages in the treatment of liver injury

Images