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Compound type natural traditional Chinese medicine preservative composition as well as preparation method and application thereof

A preservative and composition technology, which is applied in the field of compound natural traditional Chinese medicine preservative composition, can solve the problems of reducing the usage of single herbal medicines, achieve the effects of reducing usage, good application prospects, and inhibiting growth

Active Publication Date: 2017-06-13
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there is no report on the combination of schisandrin, baicalein and resveratrol used as a preservative in cosmetics and food. The present invention compounded schisandrin, resveratrol and baicalein, and found three After compounding, it has a synergistic bactericidal effect on Escherichia coli, Staphylococcus aureus and Candida albicans, which not only reduces the amount of single drug used, but also expands the antibacterial spectrum of the compound

Method used

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  • Compound type natural traditional Chinese medicine preservative composition as well as preparation method and application thereof
  • Compound type natural traditional Chinese medicine preservative composition as well as preparation method and application thereof
  • Compound type natural traditional Chinese medicine preservative composition as well as preparation method and application thereof

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Effect test

Embodiment 1

[0014] Preparation and bactericidal effect verification of the compound type natural traditional Chinese medicine antiseptic composition of embodiment 1

[0015] 1 Materials and methods

[0016] 1.1 Experimental materials and instruments

[0017] 1.1.1 Experimental strains

[0018] Escherichia coli (Escherichia coli, ATCC 8739), Staphylococcus aureus (Staphylococcusaureus, ATCC6538), Candida albicans (Candida albicans, ATCC10231), Staphylococcus epidermidis (Staphylococcus epidermidis, ATCC12228)

[0019] 1.1.2 Experimental reagents

[0020] Schizandrin B is a white crystal with a purity of 98.8%, purchased from the China Institute for Food and Drug Control.

[0021] Baicalein is a yellow needle-like crystal with a purity of 97.8%, purchased from the China Institute for Food and Drug Control.

[0022] Resveratrol is a white powder with a purity of 98%, batch number 130423 (Plant Raw Material Technology Laboratory of Beijing Technology and Business University).

[0023] 1....

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Abstract

The invention discloses a compound type natural traditional Chinese medicine preservative composition as well as a preparation method and application thereof. The compound type natural traditional Chinese medicine preservative composition provided by the invention comprises effective components including schisandrin, baicalein and resveratrol. Preferably, the weight ratio of the schisandrin to the baicalein to the resveratrol is (1-3) to (50-100) to (25-50); more preferably 1 to 50 to 25. An experiment process that the compound type natural traditional Chinese medicine preservative composition has a synergetic bactericidal effect on escherichia coli, staphylococcus aureus and Candida albicans; the dosage of a single drug is reduced; and meanwhile, the compound type natural traditional Chinese medicine preservative composition has a good broad-spectrum antibacterial property, can be used for inhibiting growth of common bacteria of cosmetics and cannot be used for completely killing staphylococcus epidermidis. The compound plant-derived preservative disclosed by the invention has the characteristics of safety and high efficiency, can be used in the fields including the cosmetics, medicines, foods and the like, especially skin-care cosmetics, and has a good application prospect.

Description

technical field [0001] The invention relates to a preservative, in particular to a compound natural traditional Chinese medicine preservative composition, which is safe and efficient, non-toxic, has no side effects, and has good broad-spectrum antibacterial properties. The preservative can not only kill cosmetics but cannot be detected The growth of bacteria, and at the same time, it has little killing effect on Staphylococcus epidermidis, which is a resident skin bacterium. Background technique [0002] At present, cosmetics with plant formulas are becoming more and more popular among consumers, and the application of plant extracts in cosmetics is also becoming more and more extensive. Traditional Chinese medicine extracts have become a new direction for the research and development of modern natural preservatives because of their antiseptic and cosmetic effects, but the problems of color, odor, stability and unclear ingredients limit their practical application (plant pre...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/49A61Q17/00A61Q19/00A61K47/10A61K47/22A23L3/3544
CPCA23L3/3544A61K8/347A61K8/4973A61K8/498A61K47/10A61K47/22A61K2800/524A61Q17/005A61Q19/00
Inventor 宋丽雅何聪芬崔树梅马强王茜贺可可
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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