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Medicine for treating children and adult cold and preparation method of medicine

A technology for adults and children, applied in the field of medicines for treating colds in children and adults and their preparation fields, can solve the effective control obstacle of the product quality of preparations, reduce the body temperature of febrile rats, the lack of quality standards for medicinal materials of cucurbit seed kernel and tragacanth gum, etc. question

Active Publication Date: 2017-07-21
XINJIANG HUASHIDAN PHARMA RES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the lack of legal medicinal material quality standards for the gourd seed kernels and tragacanth gum in the prescription, this has caused certain obstacles to the effective control of the product quality of the preparation. In view of this deficiency of the preparation, we will "compound almond kernel granules" The prescription has been modified, and the new prescription is composed of almonds, god herbs, hollyhock seeds, gum arabic, water lily, and licorice extract. We have conducted a drug efficacy and toxicology test study on the new prescription, and the results show that the drug can significantly Reduced cough frequency in mice and lowered body temperature in febrile rats

Method used

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  • Medicine for treating children and adult cold and preparation method of medicine
  • Medicine for treating children and adult cold and preparation method of medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 (based on 20g)

[0027] a. Take 4 parts of the herb and place it in an extraction container, add 6 times the amount of water, extract the volatile oil for 4 hours, filter the distilled aqueous solution for later use, collect the volatile oil, and dissolve the collected volatile oil with ethanol with a volume concentration of 95% Make into ethanol solution containing 30% volatile oil, and set aside;

[0028]b. decoct the dregs, 8 parts of almond seeds, 12 parts of hollyhock seeds and 8 parts of water lily with 6 times the amount of water once for 2 hours, filter, and combine the filtrate with the aqueous solution after distillation and filtration in step a, Concentrate to a solution with a relative density of 0.9-1.2 (measured at a temperature of 50°C), cool to room temperature, add ethanol with a volume ratio concentration of 95%, so that the alcohol content reaches a volume ratio of 30%-75%, stir well, and stand for 24 hour, filter, the filtrate decompres...

Embodiment 2

[0030] Embodiment 2 (based on 20g)

[0031] a. Take 8 parts of Herba Herbs and place them in an extraction container, add 12 times the amount of water, extract the volatile oil for 8 hours, filter the distilled aqueous solution for later use, collect the volatile oil, and add 3g of β-cyclodextrin to each 1mL of the volatile oil. Stir at 20°C for 0.5 hours, refrigerate overnight, filter with suction, dry at 40°C for 4 hours, pulverize, pass through a 100-mesh sieve to obtain the β-cyclodextrin inclusion compound of volatile oil, and set aside;

[0032] b. Add the dregs, 4 parts of almond seeds, 8 parts of hollyhock seeds and 4 parts of water lily to decoct 3 times with 12 times the amount of water, 0.5 hours each time, combine the decoction, filter, and distill and filter the filtrate with step a The resulting aqueous solutions are combined, concentrated to a relative density of 0.9-1.2, cooled to room temperature, and added with a volume concentration of 95% ethanol to make th...

Embodiment 3

[0034] Embodiment 3 (based on 20g)

[0035] a. Take 6 parts of the herb and place it in an extraction container, add 8 times the amount of water, extract the volatile oil for 5 hours, filter the distilled aqueous solution for later use, collect the volatile oil, and dissolve the collected volatile oil with ethanol with a volume concentration of 95% Make into ethanol solution containing 70% volatile oil, and set aside;

[0036] b. Add 8 times the amount of water to the dregs, 5 parts of almond kernels, 10 parts of hollyhock seeds and 6 parts of water lily, decoct twice, each time for 1 hour, filter, and distill and filter the filtrate with the aqueous solution in step a Combine and concentrate to a solution with a relative density of 0.9-1.2 (measured at a temperature of 50°C), cool to room temperature, add ethanol with a volume concentration of 95%, so that the alcohol content reaches a volume ratio of 30%-75%, stir well, and let stand After 24 hours, filter, the filtrate is ...

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Abstract

The invention relates to a medicine for treating the children and adult cold and a preparation method of the medicine. The medicine is prepared from the raw materials of badam, hyssop officinalis, hollyhock seeds, arabic gum, nymphaea candida presl and extractum glycyrrhizae. The preparation method comprises the following steps: putting the hyssop officinalis into an extractor, adding water for extraction of volatile oil, filtering a distilled aqueous solution for later use, and collecting the volatile oil for later use or cladding the collected volatile oil with beta-cyclodextrin for later use; adding water into herb residues for decoction with the badam, the hollyhock seeds and the nymphaea candida presl, combining decoctions, performing filtering, combining filtrate with distilled and filtered aqueous solution, concentrating the mixture, cooling the mixture to room temperature, adding ethyl alcohol, performing uniform stirring, performing standing and filtering, pressurizing filtrate to recycle the ethyl alcohol, concentrating the filtrate to a proper amount, adding the smashed arabic gum and extractum glycyrrhizae, adding the volatile oil or a beta-cyclodextrin inclusion of the volatile oil, and preparing the mixture into granules according to a conventional pharmaceutical method. A pharmacodynamic and toxicological experimental research shows that the medicine is obvious in treating effect and high in safety.

Description

technical field [0001] The invention relates to a medicine for treating colds of children and adults and a preparation method thereof, in particular to a Chinese patent medicine (Uighur medicine) prepared from Chinese herbal medicines, which is used for treating colds and influenza of children and adults. Background technique [0002] Cold is divided into narrow sense and broad sense. In the narrow sense, it refers to the common cold, which is a mild viral infection of the upper respiratory tract (nose and throat). In a broad sense, it also includes influenza, which is generally more severe than the common cold. Additional symptoms include fever, chills, and muscle aches. Systemic symptoms are more obvious. [0003] The common cold, also known as acute nasopharyngitis, referred to as a cold, or "cold" in traditional Chinese medicine, is the most common disease in acute upper respiratory viral infections. , the economic loss is quite huge, and can cause many complications. ...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61K9/16A61K47/69A61P11/00A61P11/14A61P29/00
CPCA61K9/1652A61K36/185A61K36/48A61K36/484A61K36/53A61K36/62A61K36/736A61K2236/53A61K2236/51A61K2236/39A61K2236/331A61K2300/00Y02A50/30
Inventor 武嘉林斯拉甫·艾白马芹周凡范文玺马小琴陈伟刘利
Owner XINJIANG HUASHIDAN PHARMA RES