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A smart phone-based immunochromatographic chip quantitative analysis system

A technology of smart phone and immunochromatography, applied in analysis materials, measuring devices, branch equipment, etc., can solve the problems of reducing equipment environmental adaptability, single data transmission mode, single equipment detection mode, etc., to improve portability and portability. The effect of strong performance and long-lasting battery life

Active Publication Date: 2019-08-06
SHANGHAI JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the supporting development equipment for immunochromatography chips is based on desktop computer processing, which has high processing speed and stable performance, but is large in size and high in cost, coupled with the limitation of fixed power supply, which is very unfavorable Outdoor use greatly reduces the environmental adaptability of these devices
In addition, the existing supporting development equipment for immunochromatography chips still has problems such as single equipment detection mode, single data transmission method, only one-to-one, and the need for professional operation.

Method used

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  • A smart phone-based immunochromatographic chip quantitative analysis system
  • A smart phone-based immunochromatographic chip quantitative analysis system
  • A smart phone-based immunochromatographic chip quantitative analysis system

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Experimental program
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Embodiment 1

[0039] In this embodiment, the smart phone-based immune chromatography chip quantitative analysis system includes a chromatography chip detection device and a detection software module data-connected with the chromatography chip detection device. The chromatography chip detection device includes a chip slot 7, an optical path module and a power supply module.

[0040] The optical path module includes a visible light source 2, an image acquisition sensor 3, a lens assembly 4, a reflective prism 5 and an ultraviolet light source 6, such as figure 2 shown. Lens assembly 4, reflective prism 5, ultraviolet light source 6, and chip groove 7 are all fixed on figure 1 In the tomographic chip detection device shown, the visible light source 2 and the image acquisition sensor 3 respectively correspond to the rear light source and the rear camera of the smart phone 1 . In this embodiment, there are two reflective prisms 5 and two ultraviolet light sources 6 . The chip groove is provi...

Embodiment approach 1

[0055] Embodiment 1: Detection of colloidal gold immunochromatography chip

[0056] When the smart phone-based immunochromatography chip quantitative analysis system is working, first start the APP program on the smart phone (that is, the detection software module), and select whether user registration is required. Registered users can enjoy detection, query and intelligent consulting services. Non-registered Users are restricted by authority and only enjoy the service of testing items.

[0057] After that, the prepared immunochromatography chip is sent into the chip slot 7. After the user selects the detection item of the colored immunochromatography chip, he enters the detection interface. The center of the detection interface is the image display area. Click the image display area in the center area to start Preview the colloidal gold immunochromatography chip. In the preview state, the user can adjust the position and direction of the chip to make the detection more accur...

Embodiment approach 2

[0058] Embodiment 2: detection of fluorescent chip

[0059] After the user logs in to the smart phone-based immunochromatographic chip quantitative analysis system, if a fluorescent immunochromatographic chip needs to be detected, the fluorescent detection item needs to be selected. This is also a characteristic function of the detection system. After entering the detection interface, the system will prompt that the UV light source needs to be turned on. If the UV light source has been turned on, just click the OK button.

[0060] The center of the detection interface is the image display area. Click the image display area to start previewing the quantum dot fluorescence immunochromatography chip. In the preview state, the user can adjust the position and direction of the chip to make the detection more accurate and faster. After clicking the detection button, the system starts to collect image information, then analyzes the signal strength, and gives a reference concentration...

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Abstract

The invention discloses an immunochromatography chip quantitative analysis system based on intelligent cellphone. The quantitative analysis system comprises a chromatography chip detection apparatus and a detection software module in data connection with the chromatography chip detection apparatus; the chromatography chip detection apparatus comprises a chip groove and an optical path module; the optical path module comprises a visible light source at back side of the cellphone, a reflection prism, a lens component, and a rear camera of the cellphone; the light emitted from the visible light source is reflected to the chips in the chip groove through the reflection prism, and then passes through the lens component, and an image acquisition signal on the chips can be obtained by the rear camera, and the analysis processing is carried out on the image acquisition signal through the detection software module. Preferably, the optical path module also comprises an ultraviolet light source. The quantitative analysis system enables quantitative determination of the colored chromatography chips which take colloidal gold as a representative, enables quantitative determination of the quantum dot fluorescence chromatography chips, has the advantages of small volume, light weight, and strong portability, by combining with the intelligent cellphone, the quantitative analysis system has the advantages of long service life and low hardware cost.

Description

technical field [0001] The invention relates to an immune chromatography chip quantitative analysis system, in particular to a smart phone-based immune chromatography chip quantitative analysis system. Background technique [0002] Point-of-care testing (POCT) refers to a new method of clinical testing performed next to the patient, which can be analyzed in real time at the sampling site, and does not require complex laboratory sample processing to obtain test results. Due to the characteristics of fast speed, simple use, and low cost of POCT detection methods, it is more and more widely used in the detection of biomarkers in the field of clinical detection. At present, POCT products have roughly experienced the following four generations: the first generation is a qualitative POCT product based on the test strip test paper method; the second generation is a semi-quantitative POCT product based on plate colorimetry or semi-quantitative instrument reading; The third generati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/558H04M1/725H04M1/02H04M1/21
CPCG01N33/558H04M1/026H04M1/21H04M1/72406
Inventor 王侃颜文强侯亚飞崔大祥
Owner SHANGHAI JIAOTONG UNIV