Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for extracting Lepidium apetalum willd alkaloid A compound from Lepidium apetalum willd seeds and application of Lepidium apetalum willd alkaloid A compound

A technology of Beitinzi and compound, which is applied in the field of extracting Beitinine A compound, and can solve problems such as unreported

Inactive Publication Date: 2017-11-17
HENAN UNIV OF CHINESE MEDICINE
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the estrogen-like effect of Bastrine A extracted from Tinglizi.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for extracting Lepidium apetalum willd alkaloid A compound from Lepidium apetalum willd seeds and application of Lepidium apetalum willd alkaloid A compound
  • Method for extracting Lepidium apetalum willd alkaloid A compound from Lepidium apetalum willd seeds and application of Lepidium apetalum willd alkaloid A compound
  • Method for extracting Lepidium apetalum willd alkaloid A compound from Lepidium apetalum willd seeds and application of Lepidium apetalum willd alkaloid A compound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Take 10kg of Tinglizi, stir-fry until the temperature is 240°C, fry for 5.5 minutes, take the fried Tinglizi, add 10 times the weight of Tinglizi to decoct and extract three times each time , each time for 1.5h, the extract was concentrated under reduced pressure to an extract, and the concentrated extract was precipitated with 20 L of ethanol with a volume concentration of 80%, and the supernatant was centrifugally filtered, concentrated until it had no alcohol smell, and put on a DianionHP-20 column , followed by gradient elution with water, volume concentration 20%, and 40% ethanol, and collected 40% ethanol eluate to obtain 40% ethanol elution site A, 40% ethanol elution site A was discretely dissolved in water, centrifugally filtered, and concentrated to the original 1 / 28-29 of the volume, through Toyopearl HW-40 column chromatography, eluting with water, flow rate 6ml / min, using a 10×180mm test tube to collect fractions, 15ml per tube, anisaldehyde-concentrated sul...

Embodiment 2

[0021] Take 5 kg of Tinglizi, stir-fry until the temperature is 240°C, fry for 5.5 minutes, take the fried Tinglizi, add 10 times the weight of Tinglizi to decoct and extract three times , each time for 1.5h, the extract was concentrated under reduced pressure to an extract, and the concentrated extract was precipitated with 14L of ethanol with a volume concentration of 80%, and the supernatant was centrifugally filtered, concentrated until it had no alcohol smell, and put on a DianionHP-20 column , followed by gradient elution with water, volume concentration 20%, and 40% ethanol, and collected 40% ethanol eluate to obtain 40% ethanol elution site A, 40% ethanol elution site A was discretely dissolved in water, centrifugally filtered, and concentrated to the original 1 / 28-29 of the volume, through Toyopearl HW-40 column chromatography, eluting with water, flow rate 6ml / min, using a 10×180mm test tube to collect fractions, 15ml per tube, anisaldehyde-concentrated sulfuric acid ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for extracting a Lepidium apetalum willd alkaloid A compound from Lepidium apetalum willd seeds and an application of the Lepidium apetalum willd alkaloid A compound. The new application of the Lepidium apetalum willd seeds can be effectively dug. According to the technical scheme, a molecular formula of the Lepidium apetalum willd alkaloid A compound extracted from the Lepidium apetalum willd seeds is C15H22N2O11[M+Na]<+> m / z429.1106, and a structural formula of the compound is shown in the description. The Lepidium apetalum willd alkaloid A compound extracted from the Lepidium apetalum willd seeds has an estrogenic function, and a new way is provided for preparation of estrogenic drugs.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a method for extracting a compound of beritrine A from Tinglizi chinensis and an application thereof. Background technique [0002] Tinglizi was first recorded in "Shen Nong's Materia Medica", listed as a low-grade herbal medicine, and is a commonly used Chinese herbal medicine. The "Tinglizi" included in the 2015 edition of "Chinese Pharmacopoeia" can be divided into north and south. Among them, the dry mature seeds of the cruciferous plant Lepidium apetalum Willd. The dry mature seeds of . are commonly called "Southern Tinglizi". The medicine tastes pungent and bitter, and is very cold in nature. It returns to the lung and bladder meridians, and has the effects of venting and relieving asthma, promoting water and reducing swelling. There are many studies on Fructus Tingli, and its chemical components mainly include flavonoids, glucosinolates, isothiocyanates, etc., while Fructus Tingl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07H19/06C07H1/08A61P5/26
CPCC07H1/08C07H19/06
Inventor 郑晓珂李孟曾梦楠李苗张靖柯张志广张贝贝冯卫生
Owner HENAN UNIV OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com