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Universal calorimetric-type biosensor

A biosensor, general-purpose technology, applied in the direction of thermal development of materials, to achieve the effects of good thermal stability, simple and compact system structure, and strong versatility

Inactive Publication Date: 2017-12-01
QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the technical defects of existing calorimetric biosensors, and provide a general-purpose calorimetric biosensor, which can be applied in enzyme analysis, biochemical detection, environmental monitoring, and online monitoring of biochemical and fermentation processes.

Method used

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Embodiment Construction

[0023] The present invention is combined with the following combined examples to illustrate the content of the present invention, but not to limit the scope of the present invention.

[0024] Such as figure 1As shown, a general-purpose calorimetric biosensor includes a thermostatic sample injection adiabatic confluence device 1, a thermally stable micro-reactor 2, a small temperature difference measurement device 3, an adiabatic base 4, an adiabatic housing 5, a positioning bolt 6, and a fastening nut 7 , a semiconductor cooling / heating device 8, a heat exchanger 9 and a fan 10, a thermostatic sample injection adiabatic confluence device 1 realizes the constant temperature of multi-stream sample injection and confluence under adiabatic conditions, and the thermally stable micro-reactor 2 maintains thermal stability The microreactor, the small temperature difference measuring device 3 is a small temperature difference measuring device using columnar, bead and spherical thermal ...

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Abstract

The invention provides a universal calorimetric-type biosensor, which is suitable for column-type, bead-type and ball-type thermal sensors. The universal calorimetric-type biosensor includes a constant-temperature sample injection and heat-insulation flow mixing device, a thermal-stable micro-reactor and a small-temperature difference metering apparatus, which are combined through quick couplings. Samples are injected through multiple channels and then is subjected to constant temperature treatment and is mixed in the constant-temperature sample injection and heat-insulation flow mixing device; the mixed sample is then fed into the thermal-stable micro-reactor for a reaction; then the small-temperature difference metering apparatus meters the temperature. The system has high universality, can adapt requirements on multi-flowing channels, multi-components, complex processes and work status adjustment, has high flexibility and good thermal-stability, has simple, compact and modularized structure, is excellent in adaptability, and can be used for on-line monitoring in the fields of enzyme analysis, biochemical detection, environment monitoring, and biochemical, fermentation and the like processes, especially calorimetric analysis and on-site measurement.

Description

technical field [0001] The invention relates to a general calorimetric biosensor, which can be applied to enzyme analysis, biochemical detection, environmental monitoring, and online monitoring of biochemical, fermentation and other processes. Background technique [0002] The development of biochemical technology requires effective analysis of various biochemical components, such as enzyme analysis, environmental monitoring, on-line determination of specific components formed or consumed during the reaction process, and raw materials and intermediate products as well as generated during the fermentation process. The continuous determination of the concentration of substances, etc. is used to control the progress of the process, etc. Due to the highly nonlinear and random nature of the above process, the application range of the mechanism and control model obtained through assumptions and experiments is limited, and it is difficult to accurately and effectively describe the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N25/20
CPCG01N25/20
Inventor 郑艺华刘君
Owner QINGDAO UNIV
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