Nasopharyngeal carcinoma primary lesion clinical target area automatic sketching method based on Grow Cut

Abstract

The invention discloses a method for automatically delineating clinical target areas of primary lesions of nasopharyngeal carcinoma based on GrowCut. The method includes the following steps: performing discrete operations on image sequences of template CT to generate corresponding three-dimensional grids; In the area, count the frequency of joint occurrences of spatially continuous grid points in the training set, obtain the corresponding correlation rules, and store them in the database; read the primary tumor data of nasopharyngeal carcinoma from new patients, and regard the primary tumor area as Seed points, set thresholds and termination conditions, innovatively use GrowCut, an algorithm originally applied to image segmentation, to simulate tumor growth, and realize automatic delineation of radiotherapy target areas. The invention can assist in the formulation of clinical radiotherapy plans, realize the automatic delineation of clinical radiotherapy target areas, meet the delineation standards for clinical applications, and improve the work efficiency of doctors. In addition, local adjustments will be used as post-processing for doctors to choose.

Description

technical field [0001] The invention relates to the fields of predicting tumor growth and simulating tumor spread, and in particular to a method for automatically delineating clinical target areas of nasopharyngeal carcinoma primary lesions based on GrowCut. Background technique [0002] Intensity Modulated Radiation Therapy (IMRT) is currently the mainstream radiotherapy technique for the treatment of nasopharyngeal carcinoma. Accurate target delineation is the prerequisite for successful clinical radiotherapy planning. The quality of life of patients after treatment has a very critical impact. At present, the delineation of the target area mainly relies on the manual delineation of doctors. The ABAS target area delineation system currently used in the hospital realizes the rigid expansion of the numerical range specified by the doctor as the preventive irradiation target area in the three-dimensional direction, and then, according to the clinical experience of the doctor,...

AI Technical Summary

Problems solved by technology

[0003] Due to the existence of objective reasons (only the perspective reference of the horizontal plane and the lack of reference of the upper and lower planes of view) and subjective reasons (subjective differences caused by different experience of different radiologists), the target area drawn manually at present results in different target volumes between different doctors. The delineation results of the districts vary widely

The determination of the follow-up treatment plan and the evaluation of the treatment effect have brought a negative impact

On the other hand, it usually takes 2-3 hours to delineate a patient's radiotherapy target area, which requires a lot of manpower and time costs, and the delineation system of ABAS is too simple, and a single distance extension is not suitable for complex structures and tissues.

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