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A mouse femoral bone defect model and its multifunctional fixation system

A fixation system and bone defect technology, applied in the medical field, can solve the problem that the model cannot be evaluated objectively

Inactive Publication Date: 2020-08-04
HEZE UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] To sum up, the existing problems in the existing technology are: the existing models cannot objectively evaluate and complete the research on bone defect and bone healing; Parameters, to establish bone defect models with different defect lengths in the middle femur of mice, and to observe the bone formation mechanism of grafts

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  • A mouse femoral bone defect model and its multifunctional fixation system
  • A mouse femoral bone defect model and its multifunctional fixation system
  • A mouse femoral bone defect model and its multifunctional fixation system

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Embodiment Construction

[0062] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0063] The application principle of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0064] Such as figure 1 As shown, the multifunctional fixation system for the mouse femur bone defect model provided by the embodiments of the present invention, the multifunctional fixation system for the mouse femur bone defect model includes:

[0065] A near-infrared light source for scanning bone defects and placing femoral biomaterial implants or drugs for treating bone injuries6;

[0066] A detection unit 7 for detecting femoral healing information at the bone defect site throu...

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Abstract

The invention belongs to the medical field, and discloses a mouse femur bone defect model and a multifunctional fixing system thereof. The fixing system comprises a near-infrared light radiation source, a detection unit, a data acquisition unit, a processor unit, a target image processing unit and a reconstruction unit. The multifunctional fixing system is used for constructing the mouse femur bone defect model. The invention aims to construct a middle and distal femur bone defect model, the preparation method of the model is simple, and the constructed bone defect model has good uniformity and repeatability. After the model is constructed, the survival rate and recovery rate of experimental animals are high, experimental animals feel less pain after an operation, activities of experimental animals are basically unaffected, there is no obvious tissue reaction, and rapid, effective, time-saving and effortless model construction is realized.

Description

technical field [0001] The invention belongs to the medical field, and in particular relates to a mouse femoral bone defect model and a multifunctional fixation system thereof. Background technique [0002] At present, femoral head necrosis is a disease in which the blood supply of the femoral head is interrupted or damaged, resulting in the death and subsequent repair of bone cells and bone marrow components, which in turn leads to structural changes of the femoral head, collapse of the femoral head, and joint dysfunction. Femoral head necrosis, also known as avascular necrosis of the femoral head, is a common refractory disease in the field of orthopedics. ONFH can be divided into two categories: traumatic and non-traumatic. The former is mainly caused by hip trauma such as femoral neck fracture and hip dislocation. The latter is mainly caused by the application of corticosteroids and alcoholism in my country. With the development of economy and society, various factors s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00A61D1/00A01K67/027
CPCA01K67/027A01K2227/105A01K2267/03A61B5/0062A61B5/4848A61B5/72A61D1/00
Inventor 张贵生孙西寨邓振旭吴红松
Owner HEZE UNIV
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