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A Novel Function Localization System Based on Cortical EEG

A cortical EEG and positioning system technology, applied in the field of neural engineering, can solve problems such as insufficient accuracy and differences in preoperative functional positioning, and achieve the effect of broadening the scope of application

Active Publication Date: 2020-12-25
BEIJING NORMAL UNIVERSITY
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Problems solved by technology

Techniques such as transcranial magnetic stimulation and functional MRI can better evaluate the relevant cortical functional areas in a non-invasive way before surgery, but they cannot replace the results obtained by the "gold standard" cortical electrical stimulation technology, except because of In addition to the insufficient accuracy caused by the limitations of their respective technical principles, they are also affected by other reasons. For example, the opening of the skull will cause slight deformation of the brain, so that the preoperative functional positioning results cannot be accurately registered with the cortical structure in the book; , During craniotomy, the cerebral cortex may undergo acute functional displacement, resulting in significant differences from preoperative functional positioning
[0003] Although cortical electrical stimulation technology is still used as a standard operating procedure for cortical function localization in neurosurgery, its reliability, implementation efficiency, and safety issues have led researchers to seek new alternatives.

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  • A Novel Function Localization System Based on Cortical EEG
  • A Novel Function Localization System Based on Cortical EEG
  • A Novel Function Localization System Based on Cortical EEG

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Embodiment

[0023] refer to figure 1 , a kind of brain function localization method based on cortical EEG and synchronous behavior recording of the present invention, concrete implementation steps are as follows:

[0024] Step 1, synchronously collect behavior tracking data and cortical EEG data.

[0025] Step 1.1 Acquisition of behavior tracking data. Different behavioral data should be collected by the device, and the present invention only introduces motor function and speech function as examples. The behavioral data corresponding to the motor function can be expressed as the myoelectric activity of the relevant limb parts. Therefore, two electrodes are placed on the skin surface of the relevant limbs, and the differential signal obtained after being directly amplified by the EEG amplifier can provide the behavioral index of the motor function. Speech function manifests itself in vocal production. Therefore, the speech output can be obtained by connecting the microphone (microphone...

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Abstract

The invention discloses a brain function positioning method based on electrocorticogram and synchronous behavior records. The method comprises the steps that behavior tracking data and electrocorticogram data are collected synchronously; a behavior strength time sequence is obtained through processing of the behavior tracking data; a brain activity time sequence is obtained through processing of the electrocorticogram data; correlation of the behavior strength sequence and the brain activity sequence under different time delays is computed; and important functional sites are screened and determined. The method has the advantages that brain function areas can be positioned rapidly and reliably and the method is applicable to inter-operation wakening and repeated survey; and clinical doctors can flexibly adjust contents used in the survey according to patients' actual situations and the method is applicable to children or patients with cognitive function damage.

Description

technical field [0001] The invention relates to the field of neural engineering, in particular to a brain function localization method based on cortical EEG and synchronous behavior recording. Background technique [0002] Neurosurgery has a good curative effect on drug-refractory epilepsy, cerebrovascular diseases and brain tumors. However, when the important functional area of ​​the brain is close to or coincides with the lesion, it will be affected by the damage operation, resulting in functional impairment. Most patients with damaged functional areas will recover within 3 months, but about 5% of patients will form permanent damage. Therefore, how to accurately locate the important functional areas of the brain is of great significance to the formulation of surgical plans and the prognosis of patients. Techniques such as transcranial magnetic stimulation and functional MRI can better evaluate the relevant cortical functional areas in a non-invasive way before surgery, b...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/0476
CPCA61B5/72A61B2576/026A61B5/369
Inventor 李小俚温建斌
Owner BEIJING NORMAL UNIVERSITY