Immune Index Indicating Carp's Anti-herpes Virus Ability

An anti-herpes virus and immune index technology, which is applied in the determination/inspection of microorganisms, instruments, and biological material analysis, etc., can solve the problems of economic loss of carp aquaculture, no effective treatment methods, and world fishery hazards, and achieve immune stability. Good, reduce economic losses, high accuracy

Active Publication Date: 2019-11-22
HEILONGJIANG RIVER FISHERY RES INST CHINESE ACADEMY OF FISHERIES SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the disease has caused serious harm to the world's fisheries, it has attracted great attention from the World Organization for Animal Health (OIE) and the World Food and Agriculture Organization (FAO), but there is still no effective treatment, and the disease has caused serious damage to the carp aquaculture industry. Economic losses

Method used

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  • Immune Index Indicating Carp's Anti-herpes Virus Ability
  • Immune Index Indicating Carp's Anti-herpes Virus Ability
  • Immune Index Indicating Carp's Anti-herpes Virus Ability

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0017] Embodiment 1: In this embodiment, the immune index indicating the anti-herpes virus ability of carps includes the activity of alkaline phosphatase (AKP).

[0018] The immune indicators used in the present invention are all innate immune (non-specific) response indicators, which can respond quickly at the initial stage of virus infection, so that the identification of resistant and susceptible individuals can be made in a short period of time after pathogenic infection, and the selection of disease-resistant strains can be accelerated. course. Moreover, the immune indicators of the present invention are all response mechanisms from the protein level. Proteins are the executors of physiological functions and the direct manifestations of life phenomena. The study of functional gene-encoded proteins will directly clarify the changes of life under pathological conditions. . Using the index of the present invention to breed anti-herpes virus strains of other carp species can...

specific Embodiment approach 2

[0019] Embodiment 2: The difference between this embodiment and Embodiment 1 is: the activity of alkaline phosphatase is the activity of alkaline phosphatase in carp spleen and / or kidney tissue. Other steps and parameters are the same as those in Embodiment 1.

specific Embodiment approach 3

[0020] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is: the immune index indicating carp anti-herpes virus ability also includes reduced glutathione (GSH) activity, total antioxidant capacity (T-AOC ) level and at least one of lysozyme (LZM) activity. Other steps and parameters are the same as those in Embodiment 1 or 2.

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Abstract

The invention discloses an immunity index for indicating cyprinid herpesvirus resistance and relates to an immunity index for indicating cyprinid virus resistance. The immunity index for indicating cyprinid herpesvirus resistance, disclosed by the invention, includes activity of alkaline phosphatase (AKP). According to the invention, the immunity index for indicating cyprinid herpesvirus resistance is found, and the activity of the infected immunity index molecule for indicating cyprinid herpesvirus resistance is consistent with the survival rate of the infected carp. Therefore, the immunity index for indicating cyprinid herpesvirus resistance, disclosed by the invention, can accurately reflect the disease resistance.

Description

technical field [0001] The invention relates to an immune index indicating carp anti-virus ability. Background technique [0002] Innate immunity is the natural immune defense function formed during the germline development and evolution of the body, that is, the non-specific defense function already possessed after birth, also known as non-specific immunity. A series of defense mechanisms formed in the long-term evolutionary process. Corresponding to it is adaptive immunity, which refers to a series of defense functions produced by contact with antigenic substances after birth. [0003] However, innate immunity is stably inherited in the germ line, so the formation and gradual enhancement of its resistance during the selection of strains is mainly due to the enhancement of its specific immunity, which has nothing to do with innate immunity; moreover, the increase of this specific immune resistance Often may lead to a relatively low level of innate immunity. [0004] Kio ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/42C12Q1/34C12Q1/26
CPCC12Q1/26C12Q1/34C12Q1/42G01N2333/90283G01N2333/916G01N2333/936
Inventor 贾智英石连玉白姗姗张金凤李池陶葛彦龙胡雪松王世会尚梅
Owner HEILONGJIANG RIVER FISHERY RES INST CHINESE ACADEMY OF FISHERIES SCI
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