Prognostic marker of gliomas circ8: 127890589|127890998 and application

A glioma and marker technology, which is applied in biochemical equipment and methods, microbial determination/examination, DNA/RNA fragments, etc., can solve the problems of poor treatment effect, poor prognosis, and unoptimistic postoperative survival rate
CN107586848AInactive Publication Date: 2018-01-16XIANGYA HOSPITAL CENT SOUTH UNIV
4 Cites 3 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
XIANGYA HOSPITAL CENT SOUTH UNIV
Publication Date
2018-01-16
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a prognostic marker of gliomas circ8: 127890589|127890998 and application, namely circRNA circ8: 127890589|127890998 reagents of detecting brain tissue sources for preparing the prognostic marker of gliomas patients. Researchers find that an expression level of the circRNA circ8: 127890589|127890998 is significantly downregulated in brain tissues of the glioma patients (P less than 0.0001). Patients with higher expression levels of circRNA circ8: 127890589|127890998 in gliomas have a higher postoperative survival rate (P equal to 0.086). Therefore, the prognostic markerof the gliomas circ8: 127890589|127890998 and the application can determine prognosis of the glioma patients by detecting the expression level of circRNA circ8: 127890589|127890998 in the glioma tissues of the glioma patients.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of biotechnology, and relates to a circRNA marker for glioma prognosis, the application of a reagent for detecting the marker to prepare a glioma prognosis preparation, and a kit. Background technique

[0002] Glioma is the most common malignant neuroepithelial cell tumor in the brain, accounting for 40.49% of intracranial tumors, and is one of the most common brain tumors in adults. From the time of diagnosis, the average life expectancy of patients with glioma is less than five years. At present, there are various treatment techniques for glioma, but due to the characteristics of fast tumor infiltration and invasion, and insensitivity to apoptosis mediated by radiotherapy and chemotherapy, the overall treatment effect is not good, the recurrence rate is high, and the prognosis is poor. Therefore, new treatments are sought. Targets and prognostic indicators are critical. At present, the diagnosis of glioma is still...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More