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A polytetrafluoroethylene coating composition for the surface of guide wire

A technology of polytetrafluoroethylene, coating composition, applied in the direction of coating, etc., can solve problems such as adverse health consequences

Active Publication Date: 2018-08-24
FOSHAN QIYOU MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Use of this recalled product may result in serious adverse health consequences

Method used

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  • A polytetrafluoroethylene coating composition for the surface of guide wire
  • A polytetrafluoroethylene coating composition for the surface of guide wire

Examples

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Effect test

preparation example Construction

[0039] The preparation method of the fluorocarbon type Gemini wetting agent includes the following steps:

[0040] (1) Add 2-(perfluorobutyl) ethyl acrylate to the reactor, raise the temperature to 100°C, slowly add the polymerization inhibitor hydroquinone, after the addition is complete, then slowly add butanediol dishrink After the addition of glycerol ether, the catalyst tetrabutylammonium bromide is added, and the reaction is kept for 12h. After the reaction is completed, it is concentrated under reduced pressure to obtain the intermediate of the fluorocarbon type Gemini wetting agent; the 2-(perfluorobutyl ) The molar ratio of ethyl acrylate to the hydroquinone, the butanediol diglycidyl ether, and the tetrabutylammonium bromide is 1:5:0.9:0.11;

[0041] (2) Add the intermediate of the fluorocarbon type Gemini wetting agent, concentrated sulfuric acid, and polyethylene glycol 400 into the reactor, increase the temperature to 140°C, keep the temperature for 7 hours, and cool t...

Embodiment 1

[0069] The polytetrafluoroethylene coating composition used on the surface of the guide wire is calculated in parts by weight. The polytetrafluoroethylene coating composition used on the surface of the guide wire includes 45 parts of PTFE emulsion, 8 parts of fluororesin, and 0.6 parts foaming agent, 0.8 parts wetting agent, 0.5 parts leveling agent, 42 parts water;

[0070] Wherein, the wetting agent is a fluorocarbon type Gemini wetting agent, a siloxane-based Gemini wetting agent, Capstone FS-30, and the fluorocarbon type Gemini wetting agent and the silicon oxygen The weight ratio of the alkyl type Gemini wetting agent and the Capstone FS-30 is 1:0.7:1.3. The raw materials for the preparation of the fluorocarbon type Gemini wetting agent include 2-(perfluorobutyl) ethyl acrylate, butyl Glycol diglycidyl ether, polyethylene glycol 400, the raw materials for preparing the siloxane-based Gemini wetting agent in the wetting agent include 1,1,3,3-tetramethyl-1,3- Divinyl disiloxa...

Embodiment 2

[0080] The polytetrafluoroethylene coating composition used on the surface of the guide wire is calculated in parts by weight. The polytetrafluoroethylene coating composition used on the surface of the guide wire includes 40 parts of PTFE emulsion, 8 parts of fluororesin, and 0.6 parts foaming agent, 0.8 parts wetting agent, 0.5 parts leveling agent, 47 parts water;

[0081] Wherein, the wetting agent is a fluorocarbon type Gemini wetting agent, a siloxane-based Gemini wetting agent, Capstone FS-30, and the fluorocarbon type Gemini wetting agent and the silicon oxygen The weight ratio of the alkyl type Gemini wetting agent and the Capstone FS-30 is 1:0.7:1.3. The raw materials for the preparation of the fluorocarbon type Gemini wetting agent include 2-(perfluorobutyl) ethyl acrylate, butyl Glycol diglycidyl ether, polyethylene glycol 400, the raw materials for preparing the siloxane-based Gemini wetting agent in the wetting agent include 1,1,3,3-tetramethyl-1,3- Divinyl disiloxa...

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Abstract

The invention provides a polytetrafluoroethylene coating composition for a guide wire surface. The polytetrafluoroethylene coating composition comprises the following components in parts by weight: 30-55 parts of PTFE emulsion, 5-15 parts of fluororesin, 0.1-1.0 parts of antifoaming agents, 0.1-1.0 parts of wetting agent, 0.1-1.0 parts of flatting agent, and 40-50 parts of water, wherein the wetting agent comprises one or more of fluorocarbon type Gemini wetting agent, siloxane type Gemini wetting agent, fluoride-containing nonionic wetting agent Tech-243, Capstone FS-3100, Capstone FS-30, Capstone FS-31, Capstone FS-50, Capstone FS-51, Capstone FS-60, and Capstone FS-61.

Description

Technical field [0001] The present invention relates to the technical field of coatings. Specifically, the present invention relates to a polytetrafluoroethylene coating composition used on the surface of a guide wire. Background technique [0002] The ideal biomedical metal material should have good lubricity and biocompatibility. In the process of intervention in the human body, biomedical metal materials will inevitably produce friction with human tissues or blood vessels. When this friction force is large, it will cause damage to the blood vessel wall and other epithelial tissues, causing pain or patient pain. Burning, and the damaged tissues are also prone to bacteria and cause inflammation. [0003] Biomedical metal materials can also cause protein adsorption during the process of intervention in the human body, causing adhesion of platelets, bacteria, etc., and the possibility of blood clotting, bacterial infection, etc., resulting in its biocompatibility not meeting the in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C09D127/18C09D7/65
CPCC08L2203/02C08L2205/02C08L2205/035C09D127/18C08L27/14C08L27/16C08L33/16C08L71/02C08L83/04
Inventor 王洪强何永继陶庆强叶翠萍潘伟凤陈芳沈友红罗小娟
Owner FOSHAN QIYOU MEDICAL TECH CO LTD
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