Novel function of ozonated surfactant and administration approach
A technology of surfactant and route of administration, applied in the field of new functions and route of administration of ozonated surfactants, can solve problems such as practical application obstacles, inability to uniformly coat or spray, etc.
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Embodiment 1
[0037] Example 1 Preparation of ozonated α-sulfounsaturated fatty acid methyl ester enteric-coated capsules
[0038] 1. Preparation of ozone gas. The invention adopts medical oxygen to prepare ozone gas through an ozone generator.
[0039] It is selected from the DRO3-A ozone machine (power≦55W) designed and produced by Xi'an Derun Biotechnology Co., Ltd.
[0040] 2. The whole process of preparing ozonated α-sulfounsaturated fatty acid methyl ester and its enteric-coated capsules must be carried out at 20-25°C to ensure that the ozonated α-sulfounsaturated fatty acid methyl ester will not undergo pyrolysis reaction.
[0041] 3. Put 3kg of α-sulfounsaturated fatty acid methyl ester into the reaction kettle; 3 / h flow rate was added, and the total reaction time was 20 hours. After the reaction is over, the residual gas is inactivated.
[0042] 4. The ozone concentration in the obtained ozonated α-sulfounsaturated fatty acid methyl ester is 40 mg / L, and it can be stored stabl...
Embodiment 2
[0047] Example 2 Preparation of ozonated sucrose unsaturated fatty acid ester quaternary ammonium salt enteric-coated capsules
[0048] 1. Preparation of ozone gas. The invention adopts medical oxygen to prepare ozone gas through an ozone generator.
[0049] It is selected from the DRO3-A ozone machine (power≦55W) designed and produced by Xi'an Derun Biotechnology Co., Ltd.
[0050] 2. The whole process of preparing the ozonated sucrose unsaturated fatty acid ester quaternary ammonium salt and its enteric-coated capsules must be carried out at 20-25°C to ensure that the ozonated sucrose unsaturated fatty acid ester quaternary ammonium salt will not undergo pyrolysis reaction.
[0051] 3. Put 3kg of sucrose unsaturated fatty acid ester quaternary ammonium salt into the reactor; 3 / h flow rate was added, and the total reaction time was 20 hours. After the reaction is over, the residual gas is inactivated.
[0052] 4. The ozone concentration in the obtained ozonated sucrose u...
Embodiment 3
[0057] Example 3 Preparation of enteric-coated capsules of ozonated α-sulfounsaturated fatty acid methyl ester and oleic acid mixture
[0058] 1. Preparation of ozone gas. The invention adopts medical oxygen to prepare ozone gas through an ozone generator.
[0059] It is selected from the DRO3-A ozone machine (power≦55W) designed and produced by Xi'an Derun Biotechnology Co., Ltd.
[0060] 2. The whole process of preparing enteric-coated capsules of ozonated α-sulfounsaturated fatty acid methyl ester and oleic acid mixture must be carried out at 20-25°C to ensure that the ozonated α-sulfounsaturated fatty acid methyl ester and oleic acid mixture will not occur pyrolysis reaction.
[0061] 3. Put 1.5kg of α-sulfounsaturated fatty acid methyl ester and 1.5kg of oleic acid into the reaction kettle; 3 / h flow rate was added, and the total reaction time was 20 hours. After the reaction is over, the residual gas is inactivated.
[0062] 4. The ozone concentration in the obtaine...
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