Medical fiber structure and medical laminate

A fiber structure and laminate material technology, applied in fiber processing, plant fiber, medical science, etc., can solve the problems of gas leakage in the reinforcement area, insufficient hemostasis, and inhibition of wound healing.

Inactive Publication Date: 2018-03-27
GUNZE LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, absorbable hemostats made from regenerated oxidized cellulose are strongly acidic, which inhibits wound healing
Moreover, even in the case of using absorbable hemostats made of regenerated oxidized cellulose, hemostasis may be insufficient, or gas leakage or liquid leakage may occur in the reinforced area

Method used

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  • Medical fiber structure and medical laminate
  • Medical fiber structure and medical laminate
  • Medical fiber structure and medical laminate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] (1) Preparation of fiber structures made of hydroxyethylated and carboxylated cellulose

[0066] A 280 μm-thick single jersey fabric made of cellulose yarn with a yarn count of 80 was bleached by hydrogen peroxide bleaching as a raw material.

[0067] Soak the bleached knitted fabric in TEMPO oxidation solution (TEMPO concentration: 20% owf, 5% sodium hypochlorite concentration: 180% owf, NaBr: 17.5 owf, pH 10 aqueous solution) at 25 °C with a bath ratio of 1:30 10 minutes for oxidation. The oxidized knitted fabric was washed with water for 3 times, and then in sodium chlorite solution (25% sodium chlorite concentration: 20% owf, CG1000 concentration: 1.0 g / L, pH 3.8 aqueous solution) for 90 minutes to carry out carboxylation. The resulting knitted fabric was washed with hot water, then with water, at 70°C with a bath ratio of 1:20 in a hydrogen peroxide / sodium borohydride solution (30% hydrogen peroxide concentration: 1% owf, sodium borohydride concentration : 5% ow...

Embodiment 2

[0086] Fabrication of medical fiber structures and medical laminates, evaluation of adhesion to damaged tissue, and stress testing were performed in the same manner as in Example 1, except that the TEMPO oxidation solution used in the TEMPO oxidation step was TEMPO oxidation solution (TEMPO concentration: 20% owf, 5% sodium hypochlorite concentration: 350% owf, sodium bromide: 17.5% owf, pH 10 aqueous solution).

[0087] Tables 1 and 2 show the results.

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Abstract

A medical fiber structure and a medical laminate are provided and herein are capable of sufficiently adhering to damaged tissue to stop bleeding and more reliably reinforcing weakened tissue by preventing air leakage or fluid leakage. The invention relates to the medical fiber structure including a fiber structure made of cellulose which is produced through etherification and carboxylation of hydroxy groups of cellulose.

Description

field of invention [0001] The present invention relates to a medical fiber structure and a medical laminate capable of sufficiently adhering to damaged tissue to stop bleeding by preventing gas leakage or liquid leakage and to more reliably reinforce weakened tissue. Background technique [0002] The most fundamental problem in the field of surgery is the hemostasis and repair of damaged or weakened organs or tissues. Bleeding from damaged organs, for example, is still treated with hemostasis and wound closure, which is the most common surgical method of hemostasis even now. Furthermore, another important issue in surgical treatment is preventing fluid leakage or gas leakage from weakened or damaged tissue. Especially in the field of thoracic surgery, it is very important to prevent gas leakage due to pneumothorax or after lung cancer resection. Specifically, pneumothorax is a difficult disease to treat because of the increased recurrence rate without appropriate treatment...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B15/04C08B11/08A61L15/28D06M13/355D06M13/11D06M11/80D06M11/50D06M11/30D06M101/06
CPCA61L15/26A61L15/28C08B11/08C08B15/04C08L1/286D04H1/4258D06L4/10D06M11/07D06M11/155D06M11/38D06M11/50D06M11/80D06M13/11D06M2101/08C08L1/04C08L67/04
Inventor 田中千晶由井美也松田晶二郎高森秀树
Owner GUNZE LTD
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