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Configuration method of blood dialysate

A technology of hemodialysis and configuration method, which is applied in the medical field, can solve the problems of patient balance and poor anticoagulation effect, and achieve the effect of reducing the risk of bleeding and improving the effect of anticoagulation

Inactive Publication Date: 2018-03-30
宋宏婷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current anticoagulation effect of dialysate is not good, and it is difficult to achieve a balance between bleeding and coagulation in vitro

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0020] Specific embodiment 1: a kind of hemodialysis fluid is characterized in that, comprises chloride ion, sodium ion, potassium ion, magnesium ion, citrate ion, glucose, calcium ion and 4,6-dichloro-5-nitro-2 -Propylthiopyrimidine, and 0.2-5% W / V of pirfenidone, hydrogen acetate ion and bicarbonate granules.

[0021] In a preferred implementation, the concentration of pirfenidone is 0.2% W / V, sodium chloride is 10% W / V, calcium chloride is 0.2% W / V, potassium chloride is 2% W / V, glucose 5% W / V, citric acid 0.1% W / V, 4,6-dichloro-5-nitro-2-propylthiopyrimidine 3% W / V, and adjust the pH to 7.2-7.3.

[0022] In another preferred embodiment, the concentrations of the substances are 15% W / V for sodium chloride, 5% W / V for calcium chloride, 5% W / V for potassium chloride, and 10% W / V for glucose , citric acid 2%W / V, 4,6-dichloro-5-nitro-2-propylthiopyrimidine 5%W / V and pirfenidone 5%W / V, while adjusting the pH to 7.2- Between 7.3.

[0023] The configuration method of the above-...

specific Embodiment 2

[0029] Specific embodiment 2: a kind of configuration method of hemodialysate, the steps are as follows:

[0030] Step 1. Repeat the dialysate cartridge with reverse osmosis water, disinfect it with alcohol, and rinse it for later use;

[0031] Step 2, according to the concentration of pirfenidone is 0.2% W / V, sodium chloride is 10% W / V, calcium chloride is 0.2% W / V, potassium chloride is 2% W / V, glucose is 5 % W / V, 0.1%W / V of citric acid, 3%W / V of 4,6-dichloro-5-nitro-2-propylthiopyrimidine, add raw materials, dissolve, and adjust the pH value to 7.2-7.3 .

[0032] Step 3, adjusting the pH concentration of the dialysate;

[0033] Step 4. Save.

[0034] In this embodiment, the pH value should be adjusted to between 7.2-7.3 to have a better anticoagulant effect.

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PUM

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Abstract

The invention discloses a configuration method of a blood dialysate and belongs to the medical field. The configuration method comprises the following steps: step 1, repeatedly flushing a dialysate tube with reverse osmosis water, disinfecting with ethyl alcohol and flushing for later use; step 2, adding raw materials according to the proportion of all components and dissolving; step 3, regulatinga PH value of the dialysate to 7.2-7.3; step 4, preserving.

Description

technical field [0001] The invention relates to the medical field, in particular to a method for configuring hemodialysate. Background technique [0002] Dialysis is a separation and purification technique that separates small molecules from biological macromolecules by the principle of small molecules diffusing into water (or buffer) through a semipermeable membrane. Dialysis therapy is a treatment method that allows the components (solute or water) in body fluids to be excreted through a semipermeable membrane. Generally, it can be divided into two types: hemodialysis and peritoneal dialysis. [0003] Hemodialysis (HD) is one of the renal replacement therapies for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body through a dialyzer composed of countless hollow fibers, and the blood and the electrolyte solution (dialysate) with a similar concentration to the body are exchanged through diffusion / convection inside and...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K9/08A61P7/08A61K33/06A61K31/7004A61K31/194A61K31/4418A61K31/505
CPCA61K33/14A61K9/08A61K31/194A61K31/4418A61K31/505A61K31/7004A61K33/06A61K2300/00
Inventor 宋宏婷
Owner 宋宏婷
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