17 results about "Citrate ion" patented technology

The invention provides coal gangue-based artificial soil as well as a preparation method and application thereof. The preparation method of the coal gangue-based artificial soil comprises the following steps: S1, modifying coal gangue by adopting a solution containing citric acid and ethylenediamine tetraacetic acid to obtain modified coal gangue; s2, preparing the modified coal gangue into artificial soil. According to the invention, the citric acid can dissolve carbonate in the coal gangue, the released carbonate can be combined with heavy metals, and citrate ions and ferric ions can form a complex to destroy the outer layer of ferric oxide of the heavy metals; ethylenediamine tetraacetic acid can permeate into mineral lattices of the coal gangue, lattice bound state heavy metal is released through octahedral Al-O bond breakage, the ethylenediamine tetraacetic acid can capture heavy metal combined with citric acid, a more stable heavy metal complex is formed, the heavy metal complex carries strong negative charges, and the heavy metal complex can be separated from the coal gangue. And electrostatic repulsion can be generated on the surface of the coal gangue with negative electricity, so that the heavy metal removal effect is improved.

This invention discloses a natural polysaccharide-based multilayer composite encapsulated probiotic and its preparation method, relating to the field of functional food and microbial preparation technology. This invention provides metabolic substrates for the probiotics through a probiotic-prebiotic co-encapsulation core located in the innermost layer, enabling them to maintain physiological activity during encapsulation. The first anionic polysaccharide encapsulation layer uses sodium alginate, which forms a three-dimensional gel network in a calcium-ion-containing curing solution. In the acidic environment of the stomach, the carboxyl groups in the calcium alginate gel undergo carboxylation, and the network shrinks and densifies, effectively blocking the invasion of hydrogen ions and pepsin, thus physically isolating the probiotics from gastric juice. When the encapsulated probiotics enter the small intestine and colon, the chitosan in the second pH-responsive composite encapsulation layer undergoes a conformational change due to amino deprotonation. Simultaneously, phosphate and citrate ions in the outer environment exchange ions with calcium alginate, achieving a triggered release of the probiotics in the colon.

The invention discloses a trigonelline metformin salt and a preparation method thereof, and the preparation method comprises the following steps: providing a resin column filled with anion exchange resin, treating the resin column with a salt solution for ion replacement activation to obtain an activated resin column, anions of the salt are chloride ions, bromide ions, acetate ions, malate ions, lactate ions, tartrate ions or citrate ions; enabling the trigonelline metformin iodized salt solution to pass through an activated resin column, and selectively collecting the exchanged solution; and carrying out concentration treatment on the collected exchanged solution to obtain the trigonelline metformin salt. In combination with a specific embodiment, compared with a trigonelline metformin iodate, the solubility of the trigonelline metformin salt prepared by the preparation method of the trigonelline metformin salt provided by the invention in water is greatly improved, so that the application range of the trigonelline metformin salt is greatly expanded.

The present disclosure provides a method for preparing a sterile hydrogel comprising a cross-linked polysaccharide, a non-cross-linked polysaccharide, or a mixture thereof, the method comprising the steps of: (1) preparing a hydrogel comprising a cross-linked polysaccharide, a non-cross-linked polysaccharide, or a mixture thereof and further comprising at least 1 mM citrate ions; and (2) sterilizing, preferably heat sterilizing, the hydrogel comprising at least 1 mM of citrate ions to obtain a sterile hydrogel comprising cross-linked polysaccharides, non-cross-linked polysaccharides or mixtures thereof.

The invention provides a fluorine-reducing and efficiency-improving leaching method for ionic rare earth, and belongs to the technical field of rare earth leaching. According to the method, coordination of aluminum and fluorine ions is reduced through competitive coordination of citrate and aluminum, and therefore the dual purposes of improving the rare earth leaching rate and reducing the fluorine ion leaching amount are achieved. Comprising the steps that a leaching agent A containing citrate ions and an inorganic salt leaching agent B are used for conducting mixed solution leaching or staged leaching on the ionic rare earth ore; the mass concentration range of the component containing citrate ions in the leaching agent A is 0.1-6 wt%, and the concentration of the inorganic salt component in the leaching agent B is 0.01-0.3 mol / L; the mixed solution is formed by mixing a leaching agent A and a leaching agent B, and the leaching agent A and the leaching agent B are adopted for staged leaching in sequence. According to the method, the rare earth concentration in the leachate can be increased, the dosage of the leaching agent is reduced, the fluorine ion leaching amount is reduced, the production requirements of high-quality rare earth products are met, and the application prospect is wide.

The present invention relates to compositions, and in particular to pharmaceutical compositions, comprising, or even consisting of, a suspension of bacteriophages of the class Caudoviricetes, the bacteriophages having lytic activity against at least one Gram-positive bacterial strain, at a titer of at least 108 PFU / mL, in a dispersing medium comprising, or even consisting of: - at least one non-ionic surfactant, and in particular a single non-ionic surfactant, selected from the polysorbate family, at a molar concentration greater than its critical micelle concentration, but not exceeding 2 mg / mL, and / or the poloxamer family, at a concentration ranging from 0.005% (w / v) to 30% (w / v); - one or more neutral salts formed from a pair of monovalent ions, the total molar concentration of which is in the range from 75 to 160 mM; - a buffer mixture imparting to the composition a pH from 6.0 to 7.9, and preferentially from 7.0 to 7.5, typically selected from hydrogen phosphate ion / dihydrogen phosphate, citric acid / citrate ion and citric acid / hydrogen phosphate ion ion pairs, wherein the molarity of the buffer mixture is in the range from 4 mM to 100 mM; - water, wherein the composition comprises less than 0.9 bacterial endotoxin units per mL and a total protein concentration of less than 0.09 mg / mL, and wherein the bacteriophage suspension in the dispersing medium has an osmolality of between 150 mOsm / kg and 600 mOsm / kg; the invention also relates to associated methods and uses.

The invention relates to a modified chitosan hydrogel microneedle patch and a preparation method and application thereof.The hydrogel microneedle patch comprises an ion-enhanced modified hydrogel microneedle matrix and a supporting substrate, and the ion-enhanced hydrogel microneedle matrix comprises a hydrogel microneedle matrix and introduced enhanced ions; the hydrogel microneedle matrix is prepared from temperature-sensitive chitosan, the enhanced ions comprise anions and / or cations, the anions comprise tripolyphosphate ions, citrate ions, carbonate ions and sulfate ions, and the cations comprise sodium ions, calcium ions, iron ions and zinc ions. The supporting substrate is prepared from chitosan. Compared with the prior art, ions are introduced to enhance the dendronized chitosan hydrogel, so that the chitosan hydrogel of which the mechanical property is remarkably improved and which has temperature responsiveness and pH responsiveness is obtained, and then the chitosan hydrogel microneedle of which the mechanical property is remarkably improved and the drug release performance is excellent is obtained.

A production method for high-purity tetrapropylammonium hydroxide, comprising the following steps: adding tetrapropylammonium halide into a raw material chamber of an electrolytic cell; and by means of electrolysis, tetrapropylammonium cations passing through a cationic membrane, entering a cathode chamber, and being combined with hydroxide ions generated at a cathode, so as to form tetrapropylammonium hydroxide to prepare a quaternary ammonium base. The raw material chamber contains a citrate ion compound. The production method for high-purity tetrapropylammonium hydroxide has the advantage of helping to improve the quality of a quaternary ammonium base product.

This invention discloses a method for preparing nickel cobalt cyanide, a Prussian blue analogue, and its application, belonging to the field of electrochromic materials technology. The purpose of this invention is to address the shortcomings of traditional co-precipitation methods for synthesizing Prussian blue analogues, which result in blocked ion migration channels, affecting their optical modulation range and color-changing response time. This invention introduces sodium citrate dihydrate as a complexing agent. By controlling the molar ratio of nickel ions to the complexing agent, the reaction rate of the system is controlled, achieving controllable synthesis of nickel cobalt cyanide particles. This not only allows citrate ions to first form a complex with nickel ions, slowly releasing nickel ions to react with cobalt cyanide ions, avoiding agglomeration and amorphous structures caused by rapid precipitation, but also facilitates ordered crystal growth, forming regular cubic nanostructures with more uniform particle size. The resulting cubic structure provides clearer ion diffusion paths and more uniform optical response, significantly improving electrochromic performance.

The invention belongs to the technical field of metal surface treatment, and particularly relates to a deplating solution for aluminum-manganese alloy and a deplating method. The invention discloses a deplating solution for an aluminum-manganese alloy, which comprises the following components: 30-70g / L of sodium hydroxide; and 20 g / L-70 g / L of sodium citrate. According to the deplating solution for the aluminum-manganese alloy and the deplating method, sodium hydroxide is adopted as a core deplating component, a strong alkaline environment is provided to guarantee that the dissolution reaction of aluminum in an aluminum-manganese alloy coating is efficiently carried out, sodium citrate serves as a key complexing agent, citric acid radical ions dissociated by the sodium citrate are strong multidentate ligands, and therefore the deplating effect is good. According to the stripping solution, through the synergistic effect of the two core components, the technical problems that an existing single sodium hydroxide stripping solution is blocked in stripping and uneven in stripping, a base material is prone to being damaged and the like are solved in a targeted mode, and a reliable solution is provided for efficient and high-quality stripping of an aluminum-manganese alloy coating.

A polishing composition for gallium oxide substrates and a polishing method, wherein the polishing composition contains silica particles, water, and polyvalent anions. The content of the polyvalent anions is 0.002 mole / liter or Jess in the polishing composition. The polyvalent anions include at least one kind of polyvalent anions selected from the group including sulfate ions, oxalate ions, citrate ions, and phosphate ions. The polishing composition for gallium oxide substrates additionally contains monovalent anions, and the content of the monovalent anions is 0.04 mole / liter or less in the polishing composition. The monovalent anions include at least one kind of monovalent anions selected from the group including nitrate ions, chloride ions, bromide ions, chlorate ions, bromide ions, acetate ions, formate ions, propionate ions, and butyrate ions. The polishing composition for gallium oxide substrates has a pH of 5.0 to 9.5 inclusive.

The invention discloses a preparation method and application of a liquid fertilizer containing complexed lignin polymerized phosphorus, and belongs to the field of liquid fertilizer.The preparation method comprises the steps that S1, pH response type gel containing bifunctional modified lignin is prepared, S2, ammonium polyphosphate basic liquid fertilizer is prepared, S3, compounding and complexing are conducted, and S4, a finished product is prepared. Wherein in the step S1, sodium alginate, low-ester pectin and bifunctional modified lignin are mixed in a water phase, a first cross-linking agent is added for a pre-coupling reaction, and a homogeneous polysaccharide-lignin solution is formed; adding a second cross-linking agent to carry out ionic cross-linking to obtain organogel loaded with the bifunctional modified lignin, and carrying out compounding and complexing by utilizing the organogel loaded with the bifunctional modified lignin; the technical problems of phase separation, poor stability, serious phosphorus fixation and rigid release behavior in the liquid fertilizer are solved through the design of bifunctional modified lignin and the synergistic effect of genipin covalent cross-linking and calcium citrate ion cross-linking.

This application discloses a hydrogel with high mechanical strength and its preparation method. A bidirectional photoinitiation system and two-dimensional conductive nanomaterial MXene are introduced into a pregel solution to initiate a free radical polymerization reaction of AAm monomers, generating PAAm chains. Combined with freeze casting, microphase separation occurs using a directionally grown ice crystal induction system, promoting aggregation and entanglement between PVA chains and between PVA and PAAm chains, forming crystalline regions. MXene nanosheets bind to PAAm and PVA chains via hydrogen bonds, constructing a preliminary hydrogel network. The gel is then immersed in a sodium citrate solution. Driven by a concentration gradient, citrate ions form strong coordination with hydroxyl groups on the PVA chains, inducing hydrogen bond cross-linking and well-defined crystalline domains in the pre-concentrated polymer chains, thus enhancing the gel's strength and modulus. The preparation method is simple and efficient, providing an effective strategy for preparing ultra-tough, high-strength, stretchable, and resilient hydrogels.

The present invention addresses the problem of providing: a polishing composition for polishing a gallium oxide substrate at a high polishing speed; and a polishing method therefor. [Solution] A polishing composition for a gallium oxide substrate, which contains silica particles, water, and multivalent anions, and wherein the content of the multivalent anions in the polishing composition is 0.002 mol / L or less. The multivalent anion is a multivalent anion including at least one type of multivalent anion selected from the group consisting of sulfate ions, oxalate ions, citrate ions, and phosphate ions. The polishing composition further contains a monovalent anion, and the content of the monovalent anion in the polishing composition is 0.04 mol / L or less. A polishing composition in which a monovalent anion is a monovalent anion including at least one type of monovalent anion selected from the group consisting of a nitrate ion, a chloride ion, a bromide ion, a chlorate ion, a bromide ion, an acetate ion, a formate ion, a propionate ion, and a butyrate ion. And the pH is from 5.0 to 9.5 (inclusive).

The invention belongs to the technical field of preparation of barium compounds, and relates to a preparation method of suspended barium sulfate. According to the method, magnesium citrate is introduced as a crystal form regulating agent in the initial stage of a barium sulfate precipitation reaction, and the flaky or fusiform barium sulfate with the high specific surface area is obtained by synergistically regulating crystal growth kinetics through magnesium ions and citrate ions. The obtained product has excellent suspension stability, high crystal purity and good redispersibility without surface modification, and is suitable for aqueous phase and organic medium systems.

The application belongs to the technical field of barium compound preparation, and relates to a preparation method of suspended barium sulfate. In the method, magnesium citrate is introduced as a crystal form regulator in the initial stage of the barium sulfate precipitation reaction, and the crystal growth kinetics is cooperatively regulated by magnesium ions and citrate ions, so that flaky or fusiform high-specific-surface-area barium sulfate is obtained. The obtained product has excellent suspension stability, high crystalline purity and good redispersibility without surface modification, and is suitable for water phase and organic medium systems.

The invention belongs to the technical field of metallurgical resource recycling, and particularly relates to a method for high-selectivity separation of phosphorus in steel slag and production of a metallurgical sintering raw material and a phosphate fertilizer. The method comprises the following steps: by taking ammonium citrate as a leaching agent, selectively dissolving a 2CaO. SiO2-3CaO. P2O5 solid solution in the steel slag under a nearly neutral condition by utilizing the strong coordination capability and pH buffer characteristic of citrate radicals of the ammonium citrate to Ca < 2 + >, and meanwhile, inhibiting the dissolution of phases such as calcium ferrite and the like, so that efficient separation of phosphorus and effective retention of calcium and iron are realized; leaching to obtain a phosphorus-rich leaching solution and leaching residues rich in iron and calcium; adding ammonia and precipitating to obtain a phosphate fertilizer, and introducing CO2 to precipitate calcium carbonate; the calcium carbonate and the leached residues are mixed to prepare a metallurgical sintering raw material, and the regenerated leachate can be recycled; the method is operated at the room temperature, steel slag modification is not needed, the phosphorus leaching rate is larger than 90%, the iron leaching rate is smaller than 5%, the alkalinity of the leached slag is larger than 3, all-component resource utilization of the steel slag and zero emission in the technological process are achieved, and remarkable economic and environmental benefits are achieved.