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Application of agave extract in the preparation of external itching and moisturizing personal care products

A technology for care products and agave, which is applied in the field of daily care products, can solve the reports that agave extract and composition skin external preparations are not found in skin antipruritic and moisturizing, and cannot form a protective film and deep moisturizing. And other issues

Active Publication Date: 2021-08-31
SHANGHAI ZIBANG BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

They have defects in some aspects, for example: although glycerin of polyols absorbs moisture in the air to achieve moisturizing effect, it cannot form a protective film and deep moisturizing effect
In addition, the researchers of this project did not find agave extracts and compositions used as skin external preparations in the skin antipruritic and moisturizing reports

Method used

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  • Application of agave extract in the preparation of external itching and moisturizing personal care products
  • Application of agave extract in the preparation of external itching and moisturizing personal care products
  • Application of agave extract in the preparation of external itching and moisturizing personal care products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0047] Embodiment 1-5 and comparative example 1-6

[0048]

[0049] In this example, the selection of the second component in the agave extract and composition of the present invention was confirmed, and its activity in inhibiting skin itching and moisturizing was carried out through the following analysis.

[0050] Antipruritic effect test

[0051] The guinea pigs were divided into 2 groups at random, 10 in each group, and divided into the embodiment group and the control group group. One day before the experiment, the samples were applied once to the dorsum of the right hind foot of the guinea pigs in each group. On the day of the experiment, use coarse sandpaper to scratch the shaved part of the animal's right hind foot, about 1cm 2 or so, and apply the sample there one more time. After 10 minutes, start dripping 0.01% histamine phosphate 0.5mL / piece on the wound surface, and then increase the concentration by 0.01%, 0.02%, 0.03%, 0.04%... every 3 minutes, each time i...

Embodiment 7-11

[0057] Element Example 7 Example 8 Example 9 Example 10 Example 11 Agave Extract (%) 70 60 50 40 30 1,3-Propanediol (%) 30 40 50 60 70

[0058] In this example, the optimal ratio of the agave extract and the second component 1,3-propanediol in the agave extract composition of the present invention is confirmed, and its improvement and moisturizing effect in terms of skin itching are achieved through the following analysis was carried out.

[0059] Embodiment 7-11 antipruritic effect (test method is the same as above)

[0060] Embodiment 7-11 moisturizing effect (test method is the same as above)

[0061] Such as Figure 3-Figure 4 As shown, it can be seen from the test results that when the ratio of agave extract to 1,3-propanediol is 60:40, it has the best effect on improving skin itching and moisturizing.

Embodiment 12-15

[0062] Examples 12-15 Personal Skin Care Compositions

[0063]

[0064]

[0065] Preparation of Personal Skin Care Composition: Add Phase A ingredients to a beaker and heat to 70-75°C while mixing. Subsequently, the ingredients of Phase B were heated to 70-75°C while mixing. Slowly pour phase B into phase A until homogeneous. Cool the mixture to 40°C, slowly add phase C and phase D while stirring, and stir evenly.

[0066] Embodiment 12-15 antipruritic effect test (test method is the same as above)

[0067] Embodiment 12-15 moisturizing effect test (test method is the same as above)

[0068] Such as Figure 5-Figure 6 As shown, it can be seen from the test results that when the agave extract composition is added in a personal care product at a ratio of 10%, it has the best effect on improving skin itching and moisturizing.

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Abstract

The invention relates to the application of agave extract in the preparation of external antipruritic and moisturizing personal care products. In the present invention, the composition obtained by mixing the agave extract and the second component achieves synergistic antipruritic and moisturizing effects. The agave extract and its composition with the second component can be used in personal care cosmetics, and has safe, effective and easy-to-absorb antipruritic and moisturizing effects.

Description

technical field [0001] The invention belongs to the technical field of daily care products, and in particular relates to the application of an agave extract in the preparation of external antipruritic and moisturizing personal care products. Background technique [0002] The skin occupies the largest surface area of ​​the body and acts as a protective covering for internal organs. Lack of proper skin care can lead to various skin problems such as dry, sagging, itchy, rough skin, pigmentation, wrinkles, etc. There are many reasons for these problems, such as environmental pollution, ultraviolet radiation, bacterial infection, skin sensitivity and so on. [0003] Under normal circumstances, due to the water absorption and barrier function of the stratum corneum, coupled with the covering effect of lipid substances secreted by sweat glands and sebaceous glands, the water is not easy to lose, and the stratum corneum can maintain a certain water content, increasing and maintaini...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9794A61K8/34A61Q19/00A61Q19/10A61P17/04
CPCA61K8/345A61K8/97A61K2800/592A61Q19/00A61Q19/10
Inventor 管书旺
Owner SHANGHAI ZIBANG BIO PHARMA CO LTD
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