Hydrogen-containing physiological saline, preparation method and uses

A physiological saline and hydrogen technology, applied in the field of medical supplies, can solve the problems of reduced nasal physiological function, mucosal damage, lack of antioxidant and anti-inflammatory effects, etc., to achieve the effect of convenient use and promotion of recovery

Pending Publication Date: 2018-04-20
SHANGHAI TONGJI HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the current nasal irrigation solution is mainly hypertonic or isotonic saline. Although it has the effect of clearing the nasal cavity and promoting wound recovery, it has no anti-oxidation and anti-inflammatory effects. Said that

Method used

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  • Hydrogen-containing physiological saline, preparation method and uses
  • Hydrogen-containing physiological saline, preparation method and uses
  • Hydrogen-containing physiological saline, preparation method and uses

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 This example relates to a preparation method of hydrogen-containing physiological saline

[0027] One, the preparation sodium chloride mass fraction is the physiological saline of 0.5%;

[0028] 2. At 20°C, pass hydrogen gas with a purity of not less than 99.9999% into the physiological saline obtained in step 1 and pass it into the physiological saline so that the hydrogen reaches a supersaturated state in the physiological saline to obtain the Hydrogen nasal care solution, at this time, the concentration of elemental hydrogen in physiological saline is 6mmol / L.

Embodiment 2

[0029] Example 2 This example relates to a method for preparing hydrogen-containing physiological saline

[0030] One, the preparation sodium chloride mass fraction is the physiological saline of 0.9%;

[0031] 2. At 20°C, pass hydrogen gas with a purity of not less than 99.9999% into the physiological saline obtained in step 1 and pass it into the physiological saline so that the hydrogen reaches a supersaturated state in the physiological saline to obtain the Hydrogen nasal care solution, at this time, the concentration of elemental hydrogen in physiological saline is 6mmol / L.

Embodiment 3

[0032] Example 3 This example relates to a preparation method of hydrogen-containing physiological saline

[0033] One, the preparation sodium chloride mass fraction is the physiological saline of 0.7%;

[0034] 2. At 20°C, pass hydrogen gas with a purity of not less than 99.9999% into the physiological saline obtained in step 1 and pass it into the physiological saline so that the hydrogen reaches a supersaturated state in the physiological saline to obtain the Hydrogen nasal care solution, at this time, the concentration of elemental hydrogen in physiological saline is 6mmol / L.

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Abstract

The present invention provides hydrogen-containing physiological saline, a preparation method and uses, wherein the hydrogen-containing physiological saline comprises physiological saline and elemental hydrogen dissolved in the physiological saline. The preparation method comprises: preparing physiological saline; and introducing hydrogen gas with a purity of not less than 99.9999% into the physiological saline at a temperature of 20 DEG C to achieve the supersaturated state of the hydrogen gas in the physiological saline so as to obtain the hydrogen-containing nasal cavity care solution. According to the present invention, the hydrogen-containing physiological saline can be used for preparing the nasal cavity irrigation solution, can promote the recovery of physiological functions of nasal mucosa through anti-oxidation and anti-inflammatory effects, and can be effectively applied after pathogenic bacteria infection, allergy, surgical trauma and other damage on nasal mucosa functions;and the hydrogen-rich saline for nasal cavity irrigation is conveniently to use, can be directly used for nasal cavity irrigation, and can be used for the nasal mucosa physiological function recoveryof chronic rhinitis, sinusitis, allergic rhinitis, nasal tumors and other diseases.

Description

technical field [0001] The invention relates to a hydrogen-containing physiological saline solution and its preparation method and application, belonging to the technical field of medical supplies. Background technique [0002] Physiological saline, a sodium chloride solution commonly used in physiology or clinical practice with an osmotic pressure equal to that of animal or human plasma, its concentration is 0.67-0.70% for amphibians, and 0.85-0.90% for mammals and humans. In medicine, saline refers to a sterile solution of sodium chloride (NaCl, more commonly known as saline). But it is only sterile when used intravenously, otherwise saline is just a saline solution. This sterile solution is commonly used for intravenous injections, contact lens irrigation, and nasal irrigation. Physiological saline also has different purposes in formulas for different uses. Physiological saline is also used in cell biology, molecular biology, and biochemistry experiments. [0003] Whe...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K9/08A61P7/08A61P11/02A61P39/06A61P37/08A61P35/00A61K33/00
CPCA61K9/0043A61K9/08A61K33/00A61K33/14A61K2300/00
Inventor 余少卿
Owner SHANGHAI TONGJI HOSPITAL
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