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Compound dexmedetomidine injection agent for dogs and preparation method thereof

A technology for dexmedetomidine and injections, applied in the field of compound dexmedetomidine injections for dogs and its preparation, to achieve the effects of increasing heart rate, reducing saliva secretion, and inhibiting muscle tremors

Inactive Publication Date: 2018-05-04
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Based on the unique pharmacological action of dexmedetomidine, the present invention overcomes the influence of the existing compound anesthetics for animals on various organ systems of animals during use

Method used

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  • Compound dexmedetomidine injection agent for dogs and preparation method thereof
  • Compound dexmedetomidine injection agent for dogs and preparation method thereof
  • Compound dexmedetomidine injection agent for dogs and preparation method thereof

Examples

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Effect test

Embodiment 1

[0021] A compound dexmedetomidine injection for dogs, the raw material formula is: dexmedetomidine 25 mg, droperidol 100 mg, atropine 10 mg, and 0.9% normal saline to 100 ml.

[0022] A method for preparing compound dexmedetomidine injection for dogs, comprising the following steps: dissolving dexmedetomidine, droperidol and atropine in 0.9% normal saline in sequence, adding 0.9% normal saline to dilute to 100ml , filtered, filled in ampoules, and sterilized.

Embodiment 2

[0024] A compound dexmedetomidine injection for dogs, the raw material formula is: dexmedetomidine 30mg, droperidol 100mg, atropine 13mg, 0.9% normal saline to 100ml.

[0025] A method for preparing compound dexmedetomidine injection for dogs, comprising the following steps: dissolving dexmedetomidine, droperidol, and atropine in an appropriate amount of 0.9% normal saline in sequence, and adding 0.9% normal saline to dilute to 100ml, filtered, filled in ampoules, and sterilized.

Embodiment 3

[0027] A compound dexmedetomidine injection for dogs, the raw material formula is: dexmedetomidine 35 mg, droperidol 150 mg, atropine 15 mg, and 0.9% normal saline to 100 ml.

[0028] A method for preparing compound dexmedetomidine injection for dogs, comprising the following steps: dissolving dexmedetomidine, droperidol, and atropine in an appropriate amount of 0.9% normal saline in sequence, and adding 0.9% normal saline to dilute to 100ml, filtered, filled in ampoules, and sterilized.

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Abstract

The invention relates to a compound dexmedetomidine injection agent for dogs and a preparation method thereof. The injection agent contains the active components including dexmedetomidine, droperidoland atropine. By integrating the advantages of each drug, the side effects caused during the single use of each drug is reduced, the rapid anesthesia induction is realized, the holding time is proper,and the dogs can rapidly revive; and the anesthesia process and the reviving process are smooth, and the injection agent is applicable to the immbilisation and induced anesthesia of the dogs. An injection provided by the invention is an intravenous medicine, can hardly influence each physiological parameter and can meet the anesthesia requirements in production practice, and furthermore, dexmedetomidine has certain protection effects to visceral organ systems such as nerves, heart and blood vessels and brain.

Description

technical field [0001] The invention belongs to the technical field of veterinary drug preparation, and in particular relates to a compound dexmedetomidine injection for dogs and a preparation method thereof. The compound dexmedetomidine injection for dogs is suitable for keeping and inducing anesthesia in dogs. Background technique [0002] The purpose of veterinary clinical anesthesia is to ensure the safety of humans and animals, eliminate pain and panic in animals, and facilitate the diagnosis and treatment of diseases. With the development of the pet industry, the influence of anesthetic drugs on various organs and tissues of animals has attracted more and more attention. The impact of anesthetics on the animal body and the safety of the time of use have become the mainstream of veterinary clinical research and development. [0003] At present, respiratory anesthesia has become the mainstream, and mask anesthesia is good, but it will increase some costs for pet owners ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4174A61K31/46A61K31/4439A61K9/08A61P25/20A61P25/04A61P25/08A61P23/00A61P29/00A61P21/02
CPCA61K9/0019A61K9/08A61K31/4174A61K31/4439A61K31/46A61K2300/00
Inventor 刘焕奇迟良王新邹明
Owner QINGDAO AGRI UNIV
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