Infusion connector for preventing infection and preparing method thereof
An infection prevention and anti-infection technology, which is applied in the direction of connecting tubes, medical equipment, and other medical equipment, can solve the problems of patients with infection, short retention time, easy bacterial invasion, etc., achieve good effect, easy operation, and avoid leakage. liquid effect
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Embodiment 1
[0035] Such as Figure 1-7 As shown, the embodiment of the present invention provides an infusion connector for preventing infection, comprising an upper housing 1, a lower housing 2 communicating with the upper housing 1, and a piston 3 containing anti-infective drugs, wherein the piston 3 is arranged on In the inner cavity of the upper housing 1.
[0036] Furthermore, the anti-infective drug is minocycline hydrochloride, rifampicin or a mixture of the two.
[0037] Among them, minocycline hydrochloride is a broad-spectrum, high-efficiency, quick-acting, and long-acting semi-synthetic antibacterial tetracycline antibiotics, which interfere with the binding of aminoacyl transfer RNA to the receptor site on the messenger RNA ribose appropriate receptor site. Synthetic, so it plays an antibacterial role, with good antibacterial activity and long half-life.
[0038] Among them, rifampicin is a common broad-spectrum antibiotic drug, which can firmly bind to b of DNA-dependent RN...
Embodiment 2
[0054] An embodiment of the present invention provides a method for preparing an infusion joint for preventing infection, which is used to prepare the infusion joint for preventing infection described in Example 1. The method specifically includes the following steps:
[0055] S1. Put two solvents, methanol with a concentration ≥ 99% and ethyl acetate with a concentration ≥ 98%, in a glass container, stir with a stirrer for 5 to 20 minutes, add anti-infective drugs into the glass container and continue stirring until fully Dissolved to prepare anti-infective liquid.
[0056] S2. The anti-infective liquid is heated with a constant temperature heater, so that the temperature of the anti-infective liquid reaches 30-60 degrees and remains stable.
[0057] S3. Completely immerse the piston carrier in the heated anti-infective liquid for 10-60 minutes, take it out, wash the remaining anti-infective liquid on the piston carrier with purified water except the incision, and then place ...
Embodiment 3
[0062] An embodiment of the present invention provides a method for preparing an infusion joint for preventing infection, which is used to prepare the infusion joint for preventing infection described in Example 1. The method specifically includes the following steps:
[0063] S1. Put two solvents, methanol with a concentration ≥ 99% and ethyl acetate with a concentration ≥ 98%, in a glass container, stir with a stirrer for 5 to 20 minutes, add anti-infective drugs into the glass container and continue stirring until fully Dissolved to prepare anti-infective liquid.
[0064] S2. The anti-infective liquid is heated with a constant temperature heater, so that the temperature of the anti-infective liquid reaches 30-60 degrees and remains stable.
[0065] S3. Completely immerse the piston carrier in the heated anti-infective liquid for 10-60 minutes, take it out, wash the rest of the anti-infective liquid on the piston carrier except the incision with purified water, and then plac...
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