Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of Lactobacillus kombu zw3 in the preparation of drugs for preventing or improving mental problems caused by stress

A technology of lactobacillus and kumiss, applied in the direction of lactobacillus, bacteria used in food preparation, application, etc., to achieve the effect of improving anxiety or depression

Active Publication Date: 2020-10-09
诺佰克(武汉)生物科技有限公司 +1
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs often cause adverse symptoms such as nausea and insomnia in patients.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of Lactobacillus kombu zw3 in the preparation of drugs for preventing or improving mental problems caused by stress
  • Application of Lactobacillus kombu zw3 in the preparation of drugs for preventing or improving mental problems caused by stress
  • Application of Lactobacillus kombu zw3 in the preparation of drugs for preventing or improving mental problems caused by stress

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Lactobacillus kefir ZW3 was inoculated in MRS medium, cultured at 30°C until the end of the logarithmic phase, and collected by centrifugation (6000rpm / min, 4°C, 8min);

[0048] Add 0.4mL sterile saline (0.85%) to the Lactobacillus kefir ZW3 collected by centrifugation, and adjust the final concentration of Lactobacillus kefir ZW3 to 1×10 while resuspending. 9 cfu / ml, that is, the medicament of the present invention for preventing or improving the mental problems caused by stress.

Embodiment 2

[0050] Lactobacillus kefir ZW3 was inoculated in MRS medium, cultured at 30°C until the end of the logarithmic phase, and collected by centrifugation (5500rpm / min, 3°C, 6min);

[0051] Add 0.8 mL of sterile saline (0.9%) to the centrifuged Lactobacillus kefir ZW3, and adjust the final concentration of Lactobacillus kefir ZW3 to 0.5×10 while resuspending. 9 cfu / ml, that is, the medicament of the present invention for preventing or improving the mental problems caused by stress.

Embodiment 3

[0053] Lactobacillus kefir ZW3 was inoculated in MRS medium, cultured at 30°C until the end of the logarithmic phase, and collected by centrifugation (6500rpm / min, 5°C, 10min);

[0054] Add 0.3 mL of sterile saline (0.8%) to the centrifuged Lactobacillus kefir ZW3, and adjust the final concentration of Lactobacillus kuispi ZW3 to 1.3×10 while resuspending. 9 cfu / ml, that is, the medicament of the present invention for preventing or improving the mental problems caused by stress.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the field of biotechnology, and in particular relates to the application of Lactobacillus kumi ZW3 in the field of pharmacy. The invention provides an application of Lactobacillus mukemi ZW3 in the preparation of medicines for preventing or improving mental problems caused by stress. The live bacteria of Lactobacillus mukeli ZW3 are used as active ingredients to prepare medically effective The accepted dosage form can significantly improve the mental problems caused by stress.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to the application of Lactobacillus kumi ZW3 in the field of pharmacy. Background technique [0002] Lactobacillus kefir ZW3 is a bacterial strain screened and isolated from kefir grains, and was preserved in the Culture Collection Center of the Institute of Microbiology, Chinese Academy of Sciences on December 18, 2008, with the preservation number CGMCC No.2809. At present, the research on Lactobacillus mukeli ZW3 mainly stays in the field of fermentation. For example, Zheng Yongna et al. have studied the application of Lactobacillus mukeli ZW3 in cowpea fermentation; the patent application number CN201110101570.6 discloses a A method for preparing fermented milk with Lactobacillus kefiri ZW3; the patent application number CN201410437848.0 discloses a method for preparing and fermenting capers with low nitrite content by using Lactobacillus kefiri ZW3. [0003] Stress can...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/747A61P25/22A61P25/24A23L33/135
CPCA23L33/135A61K35/747A23V2002/00A23V2400/11A23V2200/322A23V2250/206
Inventor 王艳萍孙也潘娅婧耿伟涛张阳
Owner 诺佰克(武汉)生物科技有限公司