86results about How to "Improve anxiety" patented technology

The invention discloses an aromatic essential oil drug for preventing and treating depression, boosting mood and improving brain function and its composition, which contains main pharmacological active ingredients: vanillin, vanillin salt or isomers of vanillin Any one, two or three mixtures can also be added with other natural spices and native plant essential oils such as rosewood, clove, benzoin essential oils and so on. The medicine of the present invention stimulates the olfactory nerve through the nose and the oral cavity to regulate the olfactory center of the brain and then affect different brain regions, so as to improve brain function, relieve depression, improve mood, and reduce suicide rate, and has quick onset, low concentration, no toxic side effect.

A process for preparing pomelo fruit juice includes such steps as peeling the pomelo fruit, grinding, deactivating enzyme, cooling, adding debittering agent to obtain juice A, grinding the mixture of red orange and carrot, deactivating enzyme, cooling to obtain juice B, mixing A with B, adding sorbic acid, essence oil and water, homogenizing, loading in containers, sterilizing at 120-130 deg.C and sealing.

The invention relates to a health product formula for solving the problems that an existing formula is single in function and general in effect. The formula comprises the following components in percentage by mass: 48%-52% of Peruvian maca powder, 26%-30% of cordyceps militaris extract, 4%-8% of cinnamon extract, 3%-7% of ginseng extract, 8%-12% of folium ginkgo extract, 0.0003-0.0007% of beta-carotene, 0.01%-0.05% of nicotinamide, 0.1%-0.3% of vitamin C, 0.013%-0.017% of vitamin E, 0.001%-0.003% of vitamin B1, 0.001%-0.003% of vitamin B6, 0.000004%-0.000008% of vitamin B12, 0.08%-0.12% of zinc gluconate and the balance of starch slurry, wherein the sum of all components is 100%. According to the formula, the final formed shape is granule, capsule or tablet; multiple requirements of a human body are considered in the formula; and the effect is good.

The invention discloses a traditional Chinese medicine extract with the anti-depression effect as well as a preparation method and application thereof. The preparation method comprises the steps thatradix bupleuri, Chinese angelicas, rhizoma atractylodis macrocephalae stir-fried with bran, white paeony roots, herba menthae and honey-fried licorice roots are taken according to the component ratio,60-90% ethanol of 6-10 times is added for extraction twice, extraction is carried out for 1-3 hours each time, filtering is carried out, and filtrates are combined and concentrated so as to obtain ethanol extraction clear paste; and water of 6-10 times are added into medicine residues for extraction twice, extraction is carried out for 1-3 hours each time, filtering is carried out, and filtratesare combined and concentrated so as to obtain water extraction clear paste, the ethanol is added into the water extraction clear paste so as to enable the ethanol content to reach 60-80%, standing iscarried out for 24 hours, and supernate is taken and concentrated so as to obtain clear paste; and the clear paste and the ethanol extraction clear paste are combined, are uniformly mixed and then areconcentrated so as to obtain thick paste, microwave decompression drying is carried out, crushing is carried out, and sieving is carried out through a 80-mesh sieve so as to obtain the traditional Chinese medicine extract. On the basis of having an exact anti-depression effect, the extract also has two novel anti-depression effect characteristics and can be applied to preparation of medicines fortreating depression.

The invention discloses an application of Activin A in preparation of medicine for treating withdrawal symptoms after mental excitation type drug addiction. An open field test and an elevated plus-maze test for researching anxiety behaviors as well as a tail suspension test and a forced swimming test for researching depression behaviors show that Activin A has a therapeutical effect on neurodegeneration diseases and can effectively relieve anxiety and depression behaviors induced by cocaine withdrawal, and further, Activin A almost does not have toxic and side effects on cells, has good development prospect and is expected to be developed into novel medicine for treating the neurodegeneration diseases, particularly the novel medicine for treating withdrawal symptoms after cocaine addiction.

The invention discloses a traditional Chinese medicine composition with functions of treating insomnia, improving senile dementia, enhancing learning and memory abilities, resisting to depression and anxiety and soothing the nerves and benefitting intelligence.The traditional Chinese medicine composition comprises Rhizoma Gastrodiae, Radix Paeoniae Alba, Radix Acanthopanacis Senticosi and Semen Ziziphi Spinosae.The traditional Chinese medicine composition can be prepared into dosage forms acceptable clinically or pharmaceutically.Animal experiments show that the traditional Chinese medicine composition can improve the sleeping function and senile dementia and enhance learning and memory abilities, and has the anti-depression and anti-anxiety effects.

The invention provides a tea drink with functions of soothing nerves, relaxing bowels and preventing three highs. The tea drink is prepared from semen ziziphi spinosae, fructus cannabis, flos sophoraeimmaturus, notoginseng flos, flowers of aspalathus Linearis(Brum.f.)R.Dahlgren, tea flowers, flos chrysanthemi, corn stigma, stalks and leaves of panax notoginseng, leaves of cyclocarya paliurus, folium mori, leaves of ampelopsis grossedentata, herba lophatheri, lotus leaves, radix puerariae, poria cocos, fructus mori albae, fructus rubi, semen raphani, fructus gardeniae, semen cassiae, fructus citrus sarcodactylis, fructus crataegi, liquorice root, fructus momordicae, bitter gourds, psidium guajave and oolong. The invention further provides a preparing method of the tea drink with the functions of soothing nerves, relaxing bowels and preventing three highs. The tea drink with the functions of soothing nerves, relaxing bowels and preventing three highs has good effects of soothing nervesand relaxing bowels, has obvious improvement effects on symptoms of neurasthenia, insomnia and dreaminess, anxiety, constipation and the like, and can prevent hypertension, hyperlipidemia and hyperglycemia after long-term taking.

The invention discloses a sleep quality improving sandalwood compound essential oil. The compound essential oil is prepared by uniformly mixing simmondsia chinensis seed oil, lavender essential oil, sandalwood essential oil and sweet orange essential oil. Pure natural plant essential oils serve as the raw materials of the compound essential oil, and the active ingredients of aromatic plants have the characteristics of strong permeability and strong solubility, can permeate through acupuncture points and are absorbed to act, so that a sleep quality improving effect is obvious; moreover, the compound essential oil is safe, does not have toxic and side effects and is suitable for long-term use.

The invention discloses a solid beverage containing N(2)-L-alanyl-L-glutamine, which is prepared from the following raw materials: N(2)-L-alanyl-L-glutamine, sucrose, taurine, arginine aspartate, lysine hydrochloride, ornithine hydrochloride, vitamin B3, vitamin B6, vitamin C, vitamin B12, sodium citrate, glucuronolactone, potassium chloride, DHA (docosahexaenoic acid) and sweetening agent. The solid beverage can supplement energy, enhance vigor and resist senility and fatigue, is composed of amino acids, vitamins, additives, microelements and the like, and is a functional beverage preparation for regulating the human functions; and the solid beverage is suitable for travel enthusiasts, athletes, manual workers and brain workers to drink.

The invention provides a nutritional supplement for relieving sports fatigue, comprising the following components by weight percent: 10-50% of phosphatidylserine, 10-35% of phosphatidylcholine and 20-70% of carbohydrates. The nutritional supplement of the invention can relieve sports fatigue, improve anxiety, improve sleep quality and reduce the physical and mental pressure.

Methods and processes are provided to make clinoptilolite into a water-soluble hydrolyzed form with electrolytes suitable for various administration routes for use in the detoxification and rejuvenation in environment arena, nutraceutical arena, and pharmaceutical arena This process includes oral, topical, tablet, pill formulas, biotech delivery and intravenous. Absorption of water-soluble hydrolyzed clinoptilolite fragments can aid in detoxification by binding to heavy metals, viruses and environmental toxins and can reduce reactive oxygen species and inflammation related to metals. The process and method described can provide an increase in energy, increase in growth factors that aid in hair, skin, and nail growth, and can provide an increase in focus, concentration, and memory. Water-soluble hydrolyzed, electrolyzed clinoptilolite fragments can be combined with one or more dietary supplements, including various vitamins, minerals, and sleep aids to rejuvenate the cells and the environment during and after detoxification.

The present disclosure provides a method and system for treating affective disorders such as depression and / or anxiety and / or related disorders through neuromodulatory intervention that includes brain targets within the orbitofrontal cortex (OFC). This method includes the application of electrical stimulation through an electrical signal generator device where the distal end of the device comprises at least one stimulating electrode in contact with the OFC. The treatment system includes patient selection, implantation of at least one stimulating electrode in contact with the OFC, acute or chronic electrical stimulation of the OFC, and evaluation of the effects of stimulation on clinical symptoms and status.

There is discloses a transgenic mouse over-expressing a potassium channel BEC1, which can be used as an effective tool for screening a substance for antidementia or a substance to improve learning and memory.Also disclosed are an in vivo screening method of a substance for antidementia or a substance to improve learning and memory, which uses the learning and memory abilities of said mouse as the index, and an in vivo screening of a substance for antianxiety, which uses acceleration of anxiety as the index.In addition, there is disclosed a method for producing a pharmaceutical composition for antidementia, learning and memory improvement use or antianxiety, using a substance capable of inhibiting the learning and memory potassium channel activity as the active ingredient which can be obtained by the aforementioned screening method of the present invention.

The invention belongs to the field of biotechnology and particularly relates to application of lactobacillus kefiranofaciens ZW3 in the fields of pharmacy and food. The invention provides applicationof lactobacillus kefiranofaciens ZW3 in preparation of medicines and foods for preventing or improving mental problems caused by stress pressure. Viable lactobacillus kefiranofaciens ZW3 serves as aneffective component to prepare dosage forms capable of being accepted in medicines and foods, and mental problems caused by stress pressure can be obviously improved.

The invention discloses the purpose of 5-aminosalicylic acid to preparation of medicines for treating depression accompanied by anxiety state. The 5-aminosalicylic acid disclosed by the invention canwell relieve the depression accompanied by anxiety state, reduce hippocampus inflammation level, contribute to increment of the treatment effect of anti-depression medicines and reduce drug side effects.

The invention relates to the technical field of food processing, in particular to a preparation method of a nutrient meal replacement biscuit. The biscuit is mainly prepared from the following raw materials: 10%-65% of wheat flour, 1%-12% of soy protein isolate, 1%-10% of shortening, 1%-8% of white granulated sugar, 1%-8% of polydextrose, 1%-10% of degreased starch, 1%-10% of eggs, 1%-4% of vegetable oil, 1%-8% of collagen peptide, 1%-10% of starch and the balance of whey protein powder, soy protein powder, whey protein, resistant dextrin, quinoa, psyllium seed husk powder, L-arabinose, stachyose, edible salt, ammonium bicarbonate, sodium bicarbonate, phospholipids, food flavor, sucralose, beta-carotene and tert-butylhydroquinone. The biscuit contains rich and balanced nutrients, and meanwhile, the biscuit tastes fragrant, has enough toughness, has effects of promoting appetite and strengthening the spleen, and is easy to digest, low in fat content, good in taste and simple in process.

The present invention discloses a probiotic composition for conditioning mood and a preparation method thereof, the composition comprising a Lactobacillus helveticus powder and the Lactobacillus helveticus metabolite powder. The probiotic composition can well regulate the mood of the person and improve anxiety and depression.

Methods for diagnosing a scoliosis (e.g., adolescent idiopathic scoliosis (AIS)) and / or a predisposition to developing a scoliosis based on the determination of the variation of osteopontin (OPN) levels induced by mechanical forces / stimuli are described.

The invention provides a no-wash antibacterial hand cleanser containing a bergamot essential oil microemulsion and a preparation method thereof. The no-wash antibacterial hand cleanser is characterized in that the no-wash antibacterial hand cleanser is prepared by the following raw materials in weight percentage: 12.5% to 25% of the bergamot essential oil microemulsion; 1% to 1.5% of carbomer; 9%to 21.5% of glycerin; 45% to 47.5% of anhydrous ethanol; and the balance of distilled water. The method better enables the application of the bergamot essential oil to the no-wash bacteriostatic handsanitizer, which can combine with ethanol for bacteriostasis, reduce skin irritation, expands the application value of bergamot essential oil, reduces the pollution of chemical bacteriostatic agents,and reduces human injury.

The invention provides an inactivated lactic acid bacteria inoculant as well as a preparation method and application thereof, and belongs to the technical field of microbial preparations. Two strainsof lactic acid bacteria, namely lactobacillus paracasei HYZQF3DS-2 and lactobacillus plantarum HYZQF1675-63, are obtained through screening and further mutagenesis treatment, the two strains of lacticacid bacteria are very suitable for thermal inactivation treatment, and fermentation process research is further carried out on the two strains of lactic acid bacteria, thereby improving the strain fermentation performance; and experiences prove that the microbial inoculum obtained after the fermentation culture of the two strains has good effects of relieving constipation and diarrhea; a meanwhile, the bacteria inoculant has the effects of improving sleep disorder, anxiety and the like, thereby having good practical application value.

An apparatus for directing a user to a predefined location, which includes a receiver arranged to receive input information identifying the predefined location as well as an output device for tangibly communicating to the user information for directing the user to the predefined location. Advantageously, the user receives direction information via tactile information transfer means.

The invention discloses a nutritional compound for improving sleep. The compound comprises zinc, calcium, magnesium, VB6, VC, L-tryptophan, VD, VE, spina date seeds, lilies and schisandra chinensis. The synergetic effects of supplementary microelements and sleep-improving components of homologous plants are utilized to facilitate human metabolism, adjust human microcirculation, eliminate dysphoria and shorten the awaking time before sleep and the sleep-falling time. The nutritional compound has the effects of calming nerves, soothing mind and keeping mental tranquility, so that the compound has a function of improving sleep. The realization of the functions has direct relation with the component selection, component compatibility and dosage rate. Due to the complexity of the central nervous system, the safety research is crucial; and except for activity research, the analysis for the safety thereof is necessary, such as, addiction and adverse effects on study memory. The functional food provided by the invention is acquired by obtaining the optimal raw material and ratio after symmetrically screening and analyzing rather than simply mixing.

The invention discloses a probiotic composition capable of reducing pressure and soothing sleep, and belongs to the field of all related food industries of probiotics. It includes Lactobacillus paracasei and gamma aminobutyric acid (GABA). The probiotic composition capable of reducing pressure and soothing sleep disclosed by the invention is used as a food supplement or medicine method for relieving pressure and improving sleep quality; the pressure-reducing and sleep-soothing probiotic composition can be used as a food supplement or medicine for improving the oxidation pressure in the resisting environment, relieving the fatigue pressure of the body in exercise training, relieving the mental pressure and improving the sleep quality.

The invention discloses application of ferroptosis inhibitor Liproxstatin-1 to preparation of medicine for treating traumatic brain injury, and belongs to the technical field of biomedicines. The system of the ferroptosis inhibitor Liproxstatin-1 illustrates a time-course changing process (from 6h to 14d) of ferroptosis-related protein expression and occurrence of iron deposits after traumatic brain injury; meanwhile, the Liproxstatin-1 is dosed through an abdominal cavity after a person suffers from traumatic brain injury for 1 hour, which proves that the Liproxstatin-1 can alleviate cerebraledema and blood-brain barrier permeability caused by the traumatic brain injury; the findings proves that the Liproxstatin-1 has an improvement effect on exercise and learning memory impairment caused by the traumatic brain injury; the confirmation shows that the Liproxstatin-1 can obviously improve anxiety and cognitive functions caused by TB1; and in addition, revelation shows that a protectioneffect of the Liproxstatin-1 is related with up-regulation of FTH1 and Nrf2 and down-regulation of expression of NOX2 caused by reversion of TB1. An evidence is provided for using of the Liproxstatin-1 as a novel medicine for treating the traumatic brain injury.

The invention relates to a pharmaceutical composition for treating pulmonary nodules and a preparation method thereof. The composition is composed of pseudostellaria root, wild buckwheat rhizome, barbat skullcap, Hedyotis diffusa, bulbus fritillariae thunbergii, prunella vulgaris and Cyperus Rotundus L. The composition is based on the disease which is characterized in that qi deficiency is the fundamental internal cause, and phlegm heat and toxic condensate are pathological products, the method of benefiting qi and detoxifying and dissolving nodules is proposed through dialectical treatment, and the effect of stabilizing and reducing nodules and preventing canceration is adjusted by adjusting the constitution of patients. The invention also provides the method for preparing the compositionand its pharmaceutical use.

The invention belongs to the technical field of health-care foods and in particular discloses jasmine flower weight-reducing tea. The jasmine flower weight-reducing tea comprises the following components in parts by mass: 23-37 parts of jasmine flower, 13-27 parts of rose flower, 3-17 parts of algae, 13-27 parts of plantain herb, 8-22 parts of raw semen coicis and 3-12 parts of raw mulberry bark. The traditional Chinese medicine weight-reducing tea disclosed by the invention is composed of multiple natural traditional Chinese medicines and is free of an additive and harmless to a human body.

The invention discloses a probiotic composition capable of improving memory, and belongs to the field of all related food industries of probiotics. The composition comprises lactobacillus paracasei and phosphatidylserine powder, wherein the combined effective dose of the lactobacillus paracasei is 10 billion to 60 billion supplemented every day, namely the amount of the lactobacillus paracasei bacteria is 10<10> cfu / day to 6 * 10<10> cfu / day, and 0.6 g to 2.6 g of phosphatidylserine powder is supplemented every day. The lactobacillus paracasei disclosed by the invention is combined with phosphatidylserine powder to be used as a food supplement or medicine composition for improving memory. The composition can improve spatial memory, improve expression of antioxidant and anti-inflammatory factors, improve anxiety, improve sleep, improve nerve cell neogenesis and repair ability, relieve brain fatigue, promote attention concentration and improve alertness and memory.

The invention discloses a pharmaceutical composition. The pharmaceutical composition comprises semen hoveniae extract product, rattan tea extract product, plum extract product, jujube kernel extract,lemon, and cane sugar. The invention also discloses applications of the pharmaceutical composition in preparation of medicine used for treating Alzheimer's Disease, and a preparation method of the pharmaceutical composition. The pharmaceutical composition is capable of increasing the level of mice Gephyrin protein, reducing mice anxiety level, and improving the cognition and distinguish disordersof Alzheimer's Disease patients, and is promising in application prospect in the field of Alzheimer's Disease treatment.