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40results about How to "Improve sleep disorders" patented technology

Sleep-improving enzymolysis substance rich in aromatic amino acid, and preparation method for sleep-improving enzymolysis substance

ActiveCN112056453AImprove sleep potentialHigh sleep potentialFood ingredient functionsProtein foodstuffs working-upSleeping disordersCentrifugation
The invention discloses a sleep-improving enzymolysis substance rich in aromatic amino acid, and a preparation method for the sleep-improving enzymolysis substance. The preparation method comprises the following steps of: mixing casein and distilled water at a mass ratio of 1:8-15, carrying out preprocessing heating, stirring and dispersion, regulating pH, adding one or multiple proteases at a proper temperature, carrying out enzymolysis for 0.5-4h, after enzyme deactivation is carried out, cooling to the room temperature, carrying out low-temperature centrifugation, taking supernate, and carrying out concentration and spray drying to obtain a finished product. By use of the sleep-improving enzymolysis substance prepared by the preparation method disclosed by the invention, a composition peptide of which the N terminal is the aromatic amino acid is obviously higher than other common casein enzymolysis substances, wherein tryptophan serves as a neurotransmitter serotonin precursor substance and is favorable for sleep, and peptide of which the N terminal is Tyr and Phe has calm activity. Through second-level mass spectrum identification peptide, the product disclosed by the inventionis rich in typical antianxiety peptide [alpha]-CZP and releases various antianxiety active and opioid active peptides, such as YL, FF and YPVEPF, can effectively assist in alleviating pressure and anxious emotion and eliminating sleep disorders.
Owner:SOUTH CHINA UNIV OF TECH +1

Head cover-type acupoint stimulation device for treating depressive sleep disorder with five-tone mind regulation

The invention discloses a head cover-type acupuncture point stimulation device for treating depressive sleep disorder by using five-tone mind regulation. The device comprises a main body and a connecting buckle plate, wherein a width adjusting mechanism is connected to the middle part of the main body; two sides of the width adjusting mechanism are provided with a headgear mechanism which is closeto the main body; and the buckle plate is arranged at the middle part of the headgear mechanism. The head cover-type acupuncture point stimulation device for treating depressive sleep disorder keepsa certain distance between the head of a patient and an earmuff mechanism, the patient is connected to a mobile phone APP through a Bluetooth device fixing sleeve, the tunes corresponding to syndrometype are selected, the corresponding brain wave stimulation is carried out on the brain through the different tunes, after the choice of the tunes is finished, the selection of the pulse emitter therapy is carried out and includes time and strength, the pulse wave stimulation is carried out on the corresponding selected acupuncture points, the related brain area is excited, the recovery and the remodeling of the related nerves are promoted, the sleep disorder and the depression symptoms are improved, and the side effect of drugs can be obviously reduced while the effective therapy is carried out.
Owner:李丽

Intelligent sleep assistance system with transcranial magnetic stimulation

The invention provides an intelligent sleep assistance system with transcranial magnetic stimulation. The system comprises a stimulation device arranged on the surface layer of the encephalic region,a scanning device capable of scanning the encephalic region and the stimulation device, a positioning device capable of positioning the stimulation device, a brain wave sensor capable of collecting abrain wave signal and a magnetic field generation device; the brain wave sensor is arranged on the surface layer of the encephalic region and connected with the magnetic field generation device, the magnetic field generation device is connected with the stimulation device, the scanning device is connected with the positioning device, and the positioning device is connected with the magnetic fieldgeneration device. According to the intelligent sleep assistance system with transcranial magnetic stimulation, the technical problems are solved that in the prior art, through precise orienteering stimulation of the target encephalic region, it is difficult to intelligently identify different states of the brain wave of the human body for achieving the sleep assistance function, and when orienteering stimulation on any encephalic region is achieved according to stimulation demands, it is difficult to dynamically adjust the frequency and intensity of the magnetic field for achieving the sleepassistance function according to the real-time state of the brain wave.
Owner:安生健康科技(天津)有限公司

Compound longan seed oral liquid, and preparation method and application thereof

The invention discloses a compound longan seed oral liquid, and a preparation method and application thereof, and provides a compound longan seed oral liquid with few side effects, an accurate curative effect and the efficacies of tranquilizing and allaying excitement and promoting sleep, and a preparation method and application thereof. Every 100 mL of the oral liquid contains 40 g of crude longan seeds and 8 g of crude spina date seeds. The preparation method of the oral liquid comprises the following steps: using longan seeds as a main raw material, and preparing a longan seed water extract through water soaking, decoction, filtration and concentration; using spina date seeds as an auxiliary raw material, and preparing a spina date alcohol extract through degreasing, 70% ethyl alcohol reflux extraction, filtration and concentration; mixing the longan seed water extract and the spina date alcohol extract according to the crude drug mass ratio of 5:1, preparing a supernatant through centrifugation, and preparing the compound longan seed oral liquid by a conventional method. The oral liquid provided by the invention uses the longan seeds and spina date seeds as raw materials, and has the efficacies of tranquilizing and allaying excitement and promoting sleep, and has an accurate curative effect and few side effects. The preparation method is simple and suitable for large-scale production.
Owner:TIANJIN UNIV OF COMMERCE

Cervical physiological curve correction cushion and manufacturing method thereof

Provided are a cervical physiological curve correction cushion and a manufacturing method thereof. The correction cushion comprises a cushion sleeve and fillers in the cushion sleeve. The fillers are composed of, by weight, 3-5 parts of agilawood powder, 3-5 parts of sandalwood powder, 4-10 parts of pterocarpus santalinus powder and 30-40 parts of tartary buckwheat hull. Containing bags with traditional Chinese medicine such as agilawood powder and pterocarpus santalinus powder are arranged in the cushion sleeve, the containing bags are connected with the cushion sleeve through connecting belts, and the containing bags can be arranged in the fillers. The correction cushion can treat and prevent various cervical vertebra diseases, has a good improving effect on sleep disorders and solves the problem in the existing correction cushion (medicine pillow) that the service life is short, toxicity can be generated if the cushion is used for a long time, and cushion cores are required to be replaced. A preventing and treating effect can be kept for a long time, and the traditional Chinese medicine components in the containing bags are slowly released to further prolong the service life. Components are simple and easy to prepare, and the cushion is especially suitable for people who sit in front of computers to work for a long time and have poor sleeping quality.
Owner:周统亮

Medicine for treating cardiac neurosis

The invention relates to medicinefor treating cardiac neurosis. The medicine is prepared from, by weight, 6 parts of fructus aurantii, 11 parts of prepared rehmannia roots, 8 parts of fructus gardeniae preparatus, 15 parts of tuber fleeceflower stems, 12 parts of danshen roots, 8 parts of rhizoma corydalis, 9 parts of Chinese dodder seeds and 7 parts of radix polygalae. According to the medicine,the fructus aurantii is used for regulating qi, dredging internal energy, removing stasis and dissipating swelling; the prepared rehmannia roots are used for nourishing yin, supplementing blood, boosting essence and replenishing the marrow; the fructus gardeniae preparatus is used for cooling blood for hemostasis; the tuber fleeceflower stems are used for tranquillizing mind by nourishing the heart, dredging collaterals and dispelling wind; the danshen roots are used for removing stasis, relieving pain, activating blood to promote menstruation, clearing away heart-fire and relieving restlessness; the rhizoma corydalis is used for invigorating blood circulation, tonifying qi and relieving pain; the Chinese dodder seeds are used for nourishing the liver and kidney, securing essence, arresting polyuria, improving eyesight and checking diarrhea; the radix polygalae is used for calming nerves, developing intelligence, eliminating phlegm and removing swelling. All the medicinal materials arecombined to be used and jointly achieve the effects of promoting qi and blood circulation, tonifying the kidney, receiving yang and tranquillizing mind by nourishing the heart. Clinical experiments indicate that by means of the medicine, cardiac neurosis can be treated safely and effectively.
Owner:陈锦清

Medlar and tuckahoe composition and preparation method thereof

The invention discloses a medlar and tuckahoe composition and a preparation method thereof. The preparation method of the composition comprises the following steps of: (1) preparing medlar, tuckahoe, hawkthorn, aspartame, citric acid and melatonin; (2) drying the medlar in vacuum, crushing the medlar and the tuckahoe together, screening the medlar and tuckahoe powder, crushing the hawkthorn, and screening the hawkthorn powder; (3) adding water into the medlar and tuckahoe powder obtained in the step (2), extracting the medlar and tuckahoe powder under microwave to obtain medlar and tuckahoe extract powder, adding aqueous solution of ethanol into the hawkthorn powder obtained in the step (2), and extracting the hawkthorn powder under microwave to obtain hawkthorn extract powder; and (4) mixing the medlar and tuckahoe extract powder, the hawkthorn extract powder, the aspartame, the citric acid and the melatonin to obtain a medicinal mixture, adding auxiliary materials acceptable in foods or pharmacy into the mixture, and mixing the materials to prepare granules, tablets or capsules. The composition can relieve sleep disorder, can also overcome adverse response when the melatonin is independently taken and relapse after a medicament is not taken, and achieves the effect of treating chloasma.
Owner:TIANJIN TIANSHI BIOLOGICAL DEV

Earthworm polypeptide health-care wine and preparation technology

The invention discloses earthworm polypeptide health-care wine and a preparation technology, and relates to the technical field of health-care wine. The health-care wine comprises the following components in weight ratio: 85 to 90 percent of Baijiu, 1.5 to 2.5 percent of earthworm polypeptide, 2 to 3 percent of rehmannia glutinosa, 2 to 3 percent of ostrea gigas thunberg, 1 to 1.5 percent of platycladus orientalis, 1 to 1.5 percent of ziziphus jujube, and 1 to 1.5 percent of asini corii colla, wherein the alcohol content of the Baijiu is greater than 55 percent; the earthworm polypeptide is an earthworm protein extract. An earthworm polypeptide component with the effect of sleep improvement is extracted from an earthworm material through the technologies of flash extraction, bienzyme hydrolysis, ozone deodorization and ultrafiltration, and is prepared into the health-care wine with obvious efficacy and small side effects through the combination with the traditional Chinese medicine components having the effect of sleep improvement, such as the rehmannia glutinosa, the ostrea gigas thunberg, the platycladus orientalis, the ziziphus jujube and the asini corii colla; and the health-care wine can effectively improve dyssomnia, and is suitable for most of crowds, high in practicability, practical, safe and reliable.
Owner:JIANGSU BULONG BIOTECH

Cervical physiological curve correction cushion and manufacturing method thereof

Provided are a cervical physiological curve correction cushion and a manufacturing method thereof. The correction cushion comprises a cushion sleeve and fillers in the cushion sleeve. The fillers are composed of, by weight, 3-5 parts of agilawood powder, 3-5 parts of sandalwood powder, 4-10 parts of pterocarpus santalinus powder and 30-40 parts of tartary buckwheat hull. Containing bags with traditional Chinese medicine such as agilawood powder and pterocarpus santalinus powder are arranged in the cushion sleeve, the containing bags are connected with the cushion sleeve through connecting belts, and the containing bags can be arranged in the fillers. The correction cushion can treat and prevent various cervical vertebra diseases, has a good improving effect on sleep disorders and solves the problem in the existing correction cushion (medicine pillow) that the service life is short, toxicity can be generated if the cushion is used for a long time, and cushion cores are required to be replaced. A preventing and treating effect can be kept for a long time, and the traditional Chinese medicine components in the containing bags are slowly released to further prolong the service life. Components are simple and easy to prepare, and the cushion is especially suitable for people who sit in front of computers to work for a long time and have poor sleeping quality.
Owner:周统亮

After-moxibustion tea capable of lowering lung qi and astringing mind and preparation method of after-moxibustion tea

The invention relates to the technical field of health-care tea, and discloses after-moxibustion tea capable of lowering lung qi and astringing mind and a preparation method of the after-moxibustion tea. The citrus tea comprises citrus reticulata blanco shells and a composition capable of lowering lung qi and astringing mind, The composition for reducing lung qi and astringing mind is prepared from 5-15 parts of acanthopanax, 5-15 parts of schisandra chinensis, 5-10 parts of radix puerariae, 5-10 parts of liquorice and 50-100 parts of tea leaves. The citrus tea has the effects of tranquilizing and allaying excitement, replenishing qi to invigorate the spleen, astringing lung qi and relieving cough and asthma, has the faint scent of the pericarpium citri reticulatae and tea, is sour, sweet and delicious, and can promote salivation after being drunk. All the medicinal components of the citrus tea are natural Chinese herbal medicines, artificially synthesized components are not added or are hardly added, and the components are non-toxic, so that the citrus tea is more suitable for long-term drinking as health-care tea. The tea is particularly suitable for being drunk in a matched mode after moxibustion, and lung qi hot dryness easily generated after moxibustion of people with some physiques is avoided.
Owner:广州市人体自愈力艾制品生物科技有限公司

Antagonist composition and application thereof in preparation of medicine for treating sleep disorder and mental disease

The invention provides an antagonist composition and application of the antagonist composition in preparation of a medicine for treating sleep disorder and mental disease. The antagonist composition comprises a CRH receptor antagonist and a glutamic acid energy receptor antagonist. The invention firstly discovers that the sleep duration/stability and fear reaction degree of REM can be changed by regulating and controlling the activity of neurons of corticotropin releasing hormone of the subthalamic nucleus or neurons of a globular pallidum area on the outer side of the downstream of the subthalamic nucleus, which indicates that the subthalamic nucleus and the cerebral area of the downstream of the subthalamic nucleus are functional regulation and control targets for coincidence of sleep disorder and dysfear-related mental diseases. The invention also finds that the subthalamic nucleus CRH neuron and the glutamic acid energy neuron have a very high coincidence ratio for the first time. Based on the above findings, the present invention combines a CRH receptor antagonist with a glutamic acid receptor antagonist to regulate CRH and glutamic acid signal transmission of subthalamic nucleus-lateral globular pallidum, thereby improving sleep disorders and mental disorder comorbidity associated with fear mood disorder.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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