579results about How to "Reliable determination" patented technology

The present invention provides an efficient way for high throughput haplotype analysis. Several polymorphic nucleic acid markers, such as SNPs, can be simultaneously and reliably determined through multiplex PCR of single nucleic acid molecules in several parallel single molecule dilutions and the consequent statistical analysis of the results from these parallel single molecule multiplex PCR reactions results in reliable determination of haplotypes present in the subject. The nucleic acid markers can be of any distance to each other on the chromosome. In addition, an approach wherein overlapping DNA markers are analyzed can be used to link smaller haplotypes into larger haplotypes. Consequently, the invention provides a powerful new tool for diagnostic haplotyping and identifying novel haplotypes.

The first sensor collects a first group of first sensor readings of first fixed size dependent on a range of a first sensor and safeguarding requirements of a vehicle. A second sensor collects a second group of second sensor readings of second fixed size dependent on a range of a second sensor and the safeguarding requirements. A reference frame manager references the first group and the second group of readings to a vehicle coordinate reference frame. An integration module establishes a composite grid referenced to the ground based on a spatially aligned integration of the readings of the first group and the second group. A update module refreshes the composite grid upon material movement of the vehicle such that the global occupancy of each cell in the composite grid varies in accordance with the particular location of the vehicle on the terrain.

The present invention provides an efficient way for high throughput haplotype analysis. Several polymorphic nucleic add markers, such as SNPs, can be simultaneously and reliably determined through multiplex PCR of single nucleic acid molecules in several parallel single molecule dilutions and the consequent statistical analysis of the results from these parallel single molecule multiplex PCR reactions results in reliable determination of haplotypes present in the subject. The nucleic acid markers can be of any distance to each other on the chromosome. In addition, an approach wherein overlapping DNA markers are analyzed can be used to link smaller haplotypes into larger haplotypes. Consequently, the invention provides a powerful new tool for diagnostic haplotyping and identifying novel haplotypes.

Upon receiving an acknowledgement after retransmission of a data segment, an acknowledgement number contained in the acknowledgement is compared with an acknowledgment number expected to be contained in an acknowledgement pertaining to the retransmitted data segment. When the former is larger than the latter, it is determined that the acknowledgement pertains to a data segment that was originally transmitted.

Techniques are provided for detecting the circadian state of a patient using an implantable medical device based on selected blood carbon dioxide (CO2) parameters. In one example, the implantable device tracks changes in end tidal CO2 (etCO2) levels and changes in maximum variations of pCO2 levels per breathing cycle (ΔcycleCO2) over the course of the day and determines the circadian state based thereon. It has been found that average etCO2 levels are generally highest and average ΔcycleCO2 levels are generally lowest while a patient is asleep and opposite while a patient is awake. Hence, by tracking changes in average etCO2 and ΔcycleCO2 levels over the course of the day, circadian states can be detected. Minute ventilation and activity levels are used to assist in the determination of the circadian state. Additional techniques are directed to detecting the stage of sleep.

The invention relates to a method for supporting location determination of a mobile station, in which method location data are stored in and deleted from a memory, each location data item describing the location of the mobile station measured at a given measuring moment. Furthermore, in the method, a distance parameter and / or a target level corresponding to the distance parameter is determined at least for some of the stored location data; and deletion of the location data is at least partly based on the distance parameter and target level.

The first sensor collects a first group of first sensor readings of first fixed size dependent on a range of a first sensor and safeguarding requirements of a vehicle. A second sensor collects a second group of second sensor readings of second fixed size dependent on a range of a second sensor and the safeguarding requirements. A reference frame manager references the first group and the second group of readings to a vehicle coordinate reference frame. An integration module establishes a composite grid referenced to the ground based on a spatially aligned integration of the readings of the first group and the second group. A update module refreshes the composite grid upon material movement of the vehicle such that the global occupancy of each cell in the composite grid varies in accordance with the particular location of the vehicle on the terrain.

An alarm (35) provided by a fall detection system (2) may be caused by an accidental drop of the system. Therefore prior to issuing the alarm the fall detection system a confirmation is needed that a potential fall originates from a fall detection system that is worn by a user (4). A fall of a fall detection system that is not attached to a user is characterized by the occurrence of one or more full rotations of the system. Said rotations are identified by analyzing the output signal of a magnetometer, and by detecting a periodicity in said output signal. The fall detection system (2) provides the alarm in dependence of an identified absence of at least one full rotation.

A touch screen (10) is disclosed comprising a plurality of light emitters (Lo . . . L15) and light detectors (So . . . S11) arranged around a periphery thereof. The position, shape and size of objects (16) may be determined by switching the light emitters on one-by-one and detecting shadows (18) caused by the objects. The objects comprise at least a first part with optical properties of IV a first type and a second part with optical properties of a second different type. By determining the optical phenomena caused by the second part, the orientation of the objects may be determined and / or the objects may be recognized or identified.

The present invention relates to a method of monitoring the gate opening and closing time on line by a high-voltage circuit breaker. The inception time for the breaker gate opening and closing coil with electricity can be obtained through the voltage telecommand sampling of the breaker gate opening and closing coil, the time for the separation and connection of breaker head can be obtained through three-phase voltage telecommand sampling of capacitance sensor of high-voltage electricity-carrying display device that is arranged on the electric power transmission lines. The time gap between the inception time of breaker gat closing coil with electricity and the finish time of separation of breaker head is calculated, then the gate opening time is worked out; the time gap between the inception time of breaker gate closing coil with electricity and the finish time of jointing of breaker head is calculated, then the gate closing time is worked out. The method of the present invention bases on the telecommand sampling of voltage signal; brings the operating facilities of electric power system into full play; and overcomes the shortcomings of previous online monitoring methods; thereby making the verification of time point more conveniently and accurately, and reducing the cost, thus being favorable for the realization of state repairing of the breaker.

An immobilizer ECU (20) compares an internally stored reference code with a key code transmitted from a key (10). An engine ECU (24) transmits a rolling code A when an engine speed reaches 500 rpm. The immobilizer ECU (20) transmits a rolling code B when the codes coincide with each other. The engine ECU (24) will stop an engine if it cannot receive the rolling code B within a prescribed period of time. Further, there is provided a counter CIMMOF which is incremented at the beginning of such a process. The counter CIMMOF is reset only when the process is normally completed. If an ignition is turned off prior to transmission and reception of the rolling codes, the counter CIMMOF will be counted up. According to a value of the counter CIMMOF, a period of waiting for the rolling code B is gradually shortened. Further, when the process is completed or a backup power supply to a backup memory (24d) is cut off, a time to transmit and receive the rolling codes is advanced. Thus, the situation where the engine will be able to start due to disconnection of a communication line or the like is prevented.

The invention discloses a method for automatically determining a rescue path of an expressway network. The method comprises the following steps of: 1, after a traffic accident, acquiring information of an accident site, information of peripheral emergency rescue points and information of a road network; 2, searching a path which has the shortest distance from a peripheral rescue point to an accident point and serves as an initial backup rescue path from the expressway network according to the position of the accident point and the position of the peripheral rescue point; and 3, determining a traffic stream direction influenced by the traffic accident according to lane occupied positions and traffic stream directions of the occupied lanes on the accident site, and acquiring a road condition of the accident site, the number of jammed lanes of the accident site and the position of the accident point. By the method, a rescue path decision scheme in the expressway network of emergency resources can be generated automatically, so that the emergency resources can be transported to the accident site immediately, the emergency rescue efficiency can be improved, and casualties and property loss can be reduced.

An apparatus and method for efficiently metering and transferring a cryogenic liquid, such as liquefied natural gas, from a storage vessel to, for example, a vehicle fuel tank. The apparatus incorporates a programmable controller, a motor-driven pump and a network of conduits with motor-operated valves and liquid sensors for effecting a priming of the pump with liquid free of vapor and a cool-down of the flow passages prior to a transfer operation for ensuring that a vapor-free liquid is delivered. A pair of flow meters, one for liquid and the other for returned vapor, allows a reliable determination of the amount of liquid delivered to-and remaining in-a receiving vessel. The apparatus employs a delivery nozzle with quick-disconnect valved fittings and a delivery nozzle incorporating features which allow it to be handled by an operator without the use of heavy gloves. The method of transferring a cryogenic liquid employs an operating sequence with programmed time delays for ensuring that the liquid pump is properly primed and that the transfer apparatus is cooled down before liquid transfer begins.

A method of filtering glints by processing an image of a user's cornea to obtain coordinates of desired glints from a configuration of light sources, comprising processing an image, in a first image space, of a user's cornea to determine coordinates of respective multiple positions of glints; and iteratively: selecting from the coordinates a first and a second set of coordinates; computing from the first set of coordinates a transformation that transforms the first set of coordinates into first coordinates of a predetermined spatial configuration; and testing whether the transformation transforms also the second set into positions that match second positions of the predetermined configuration. The coordinates of the desired glints are selected as those first and second sets which are transformed into coordinates that match the first and second coordinates of the predetermined configuration. The method is based on a geometrical homography and is expedient for robust gaze estimation in connection with e.g. eye tracking.

An apparatus and method for recognizing presence of an object is provided, the apparatus and method are mounted on or implemented a vehicle. In the apparatus and method, by scanning a beam-shaped electromagnetic wave, data showing reflection intensities of reflected waves and distances between the vehicle and objects outside the vehicle are obtained. Based on the detected data, characteristics presented by frequency distributions of the distances and intensity frequency distributions of the refection intensities obtained in multiple rows in a field of view in the height direction of the vehicle. The characteristics depend on an angle of the electromagnetic wave to a road on which the vehicle travels. It is determined that the characteristics are obtained from the road when the characteristics meet predetermined requirements.

A circuit arrangement (1), a detection circuit (50, 70) and an LED driver circuit (100, 110) is disclosed for operating at least one lighting unit, such as an LED unit, with a phase-cut operating voltage. The circuit arrangement (1) comprising at least an input (6) for receiving a phase-cut operating voltage from said power supply and / or an output (7) for connection to said at least one lighting unit and a pulse injection circuit, configured to determine a phase-cut operation of said power supply and to draw a current pulse from said power supply within a delay time between 200-700 μs after said phase-cut operation to provide a stable operation of said LED unit with the phase-cut power supply. The detection circuit (50,70) comprises at least an input (6) for receiving a phase-cut operating voltage from said power supply and a lamp compatibility detector (52, 72), configured to determine the presence of a parallel lamp (57), connected in parallel with the detection circuit (50, 70) to said phase-cut power supply during operation and to provide a compatibility signal to a LED driver circuit (100, 110) corresponding to the determination of said parallel lamp (57), so that said driver circuit (100, 110) is set between a normal operating mode and a compatibility mode in dependence of the presence of said parallel lamp (57).

A method and a device for measuring humidity may be suitable for determining the relative humidity in the high-humidity range. The device includes a sensor device, as well as sequential electronics post-connected to the same. The sensor device includes a capacitive humidity-sensor element, a temperature-sensor element, and a heating element, the humidity-sensor element being heated in at least one part of the humidity-measuring range. The ambient temperature is further ascertained by the sequential electronics, from the heating power required in the heating mode, as well as from the measured, local sensor device temperature, in order to further determine the relative humidity.

The present invention provides an efficient way for high throughput haplotype analysis. Several polymorphic nucleic acid markers, such as SNPs, can be simultaneously and reliably determined through multiplex PCR of single nucleic acid molecules in several parallel single molecule dilutions and the consequent statistical analysis of the results from these parallel single molecule multiplex PCR reactions results in reliable determination of haplotypes present in the subject. The nucleic acid markers can be of any distance to each other on the chromosome. In addition, an approach wherein overlapping DNA markers are analyzed can be used to link smaller haplotypes into larger haplotypes. Consequently, the invention provides a powerful new tool for diagnostic haplotyping and identifying novel haplotypes.

An image creating apparatus capable of creating cell images allowing reliable determination of cell structures in a cell is provided. This image creating apparatus comprises an image pickup portion picking up a plurality of images of a cell on different focal positions and an image synthesizing portion classifying the plurality of images picked up by the image pickup portion into a plurality of depth ranges as to the focal direction and synthesizing the plurality of images belonging to the respective ones of the plurality of depth ranges every plurality of depth ranges thereby creating focus-synthesized images in focus over corresponding depth ranges every plurality of depth ranges.

A system and method for mass analysis of an ion beam. The system includes a mass selector, at least one multipole ion guide, and a mass analyzer. In the system and method, precursor ions are selected with a desired mass to charge ratio. Electrons are injected into the multipole ion guide. The precursor ions are fragmented into product ions via electron capture dissociation from the injected electrons. The product ions are passed to a mass analyzer for a mass analysis.

A method and apparatus for preparing uniform carbon-13 labeled biomass using a water soluble carbon-13 labeled carbon source, such as a [13C]-bicarbonate or [13C]-carbonate salt, is disclosed. The biomass is prepared in one or more sterile carboys filled with growth medium, in which acidity, oxygen, and biomass density are carefully monitored and maintained. By using a solid, water-soluble [13C]-bicarbonate or [13C]-carbonate salt as the sole carbon source, a biomass is provided which is uniformly and efficiently labeled with carbon-13. This method and apparatus is particularly useful for the growth of an edible carbon-13 labeled algal mass, with Spirulina platensis being a specific alga species. The biomass may be prepared in conformance with FDA current good manufacturing practice regulations, and may be harvested and formed into lyophilized bulk drug powder which may be further processed into various drug product forms which are useful for diagnostic tests or in pharmaceutical compositions.

Transmitting an acknowledgement / negative acknowledgement (ACK / NACK) signal in association with a packet transmitted on an uplink is disclosed. The method includes the steps of receiving a packet transmitted from a user equipment, decoding the packet, and determining whether the packet has been successfully decoded, transmitting an ACK signal or a NACK signal, based on the decoding result. Different transmission powers are allocated for the ACK signal and the NACK signal. Alternatively, the transmission power for the NACK signal selectively has an OFF level. The present invention optimizes the transmission powers for downlink ACK / NACK signals in accordance with the required reception quality of each of the ACK / NACK signals, and thus, enables the system to operate efficiently.

A radar level gauging principle including transmitting at least two time separated carrier wave pulses having equal carrier frequencies, determining a change in phase shift associated with two pulses in the transmit signals having equal frequencies, comparing the change with a threshold value, and depending on a result of the comparing step, determining the distance based on a relationship between the transmit signals and the return signals.By comparing the actual phase resulting from two substantially identical pulses transmitted a certain time apart, an indication of a change of filling level can be obtained. This indication can then be used to initiate a full measurement cycle.

A camera system for detecting the surroundings of a vehicle through a vehicle window pane (1), having a camera (2) having an image sensor (4), a first optical radiation (6) generated by the vehicle surroundings detectable by a sensor surface (10) of the image sensor (4), and a radiation source (3) for emitting a second optical radiation (7). At least a portion of the emitted second optical radiation (7) is detectable by the sensor surface (10) of the image sensor (4), and the portion of the second optical radiation (7) detected by the sensor surface (10) is a function of a state of window pane (1). The first and second optical radiation (6, 7) are jointly detectable via at least one partial area (8, 9) of the sensor surface (10). A method is also provided for detecting the surroundings of a vehicle employing the camera system.

An apparatus for determining a volume of a construction material sample is provided, comprising at least one sample-interacting device configured to interact with the construction material sample so as to determine at least one surface characteristic thereof. A computer device is configured to be capable of receiving the at least one surface characteristic from the at least one sample-interacting device, and to manipulate the at least one surface characteristic so as to form a three-dimensional representation of the construction material sample. The computer device is further configured to determine the volume of the construction material sample from the three-dimensional representation thereof. By determining the mass of the construction material sample, the density of the construction material sample can be provided. An associated method is also provided.

An image creating apparatus capable of creating cell images allowing reliable determination of cell structures in a cell is provided. This image creating apparatus comprises an image pickup portion picking up a plurality of images of a cell on different focal positions and an image synthesizing portion classifying the plurality of images picked up by the image pickup portion into a plurality of depth ranges as to the focal direction and synthesizing the plurality of images belonging to the respective ones of the plurality of depth ranges every plurality of depth ranges thereby creating focus-synthesized images in focus over corresponding depth ranges every plurality of depth ranges.

The invention relates to an elevator comprising an elevator car that is guided inside an elevator shaft on guide rails. Said elevator also comprises electronics for inter alia travel control or regulation and an emergency braking device for preventing excess speed of the elevator car. Said emergency braking device has a braking device and a detector unit (11) the signal of which actuates the braking device when the elevator car reaches an excess speed. The detector unit (9, 11) comprises at least two wheels (8) that rest against a guide rail (2), each driving a respective detector (11) the signal of which is a measure for the rotational angle or rotational speed of the corresponding wheel. The electronics are adapted to functionally utilize the detector signal.; For this purpose, at least one detector signal is used during operation of the elevator within the admissible speed range for determining at least travel, speed and / or acceleration variable of the elevator car influencing the operation of the elevator system. The electronics actuate the braking device as soon as at least one of the detectors (11), by way of its detector signal, indicates an excess speed of the elevator car outside the admissible speed range.

The invention relates to a radiation detection device for integrating the number of optical photons in a light pulse. A system, a method and a computer program product are also disclosed. The radiation detection device comprises an optical detector pixel array which has a plurality of pixel cells that can be triggered by optical photons, a plurality of pixel cell trigger state sensing circuits, and a summing unit. Each pixel cell trigger state sensing circuit generates a digital signal having either a first predetermined amplitude indicative of a triggered pixel cell, or a second predetermined amplitude indicative of a non-triggered pixel cell. The summing unit generates an analogue signal whose amplitude corresponds to the number of triggered pixel cells and thereby performs the desired integration. The analogue signal may further cause a timing unit to generate a timestamp when a predetermined accumulated optical photon count condition is met.