Traditional Chinese medicine composition for treating hypertension, high blood fat, high blood sugar and high blood viscosity and preparation method thereof

A composition and a technique for hyperlipidemia are applied in the fields of traditional Chinese medicine compositions for hyperglycemia and hyperviscosity and preparation thereof, hyperlipidemia, and treatment of hypertension, and can solve the problems of insufficient curative effect, discomfort of people with negative constitution, and no effective enrichment. Effective ingredients and other issues, to achieve the effect of good technical effect, improved bioavailability, and improved stability

Active Publication Date: 2018-06-01
内蒙古蒙奇药业有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The inventors of the present application found that the curative effect of traditional Qingxue Bawei Tablets is not good enough, and the whole prescription focuses on heat-clearing drugs, and the medicinal

Method used

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  • Traditional Chinese medicine composition for treating hypertension, high blood fat, high blood sugar and high blood viscosity and preparation method thereof
  • Traditional Chinese medicine composition for treating hypertension, high blood fat, high blood sugar and high blood viscosity and preparation method thereof
  • Traditional Chinese medicine composition for treating hypertension, high blood fat, high blood sugar and high blood viscosity and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] (1) Take 10 parts of Hanshuishi, 10 parts of comfrey, 10 parts of Rehmannia glutinosa, 1 part of Tumuxiang, 1 part of artificial bezoar, 4 parts of gardenia, 8 parts of Chinese yam, 1 part of Qumai, 1 part of gypsum, and 1 part of licorice;

[0088] (2) Grind artificial bezoar and cold water stone separately, and pass through a 120-mesh sieve;

[0089] (3) Comfrey add 5 times the amount of 80% ethanol for reflux extraction twice, the first time is 1 hour, the second time is 1 hour, filter, combine the filtrate, recover the ethanol until the extract contains 0.3g / ml crude drug, filter After that, the alcohol extract was added to the macroporous adsorption resin column for adsorption at a flow rate of 2BV / h, left to stand for 4 hours, then washed with an aqueous solution of 5 times the column volume at a flow rate of 3BV / h, and then washed with 40% ethanol solution Elute at a flow rate of 2BV / h, and the elution ratio of ethanol is 6 times. Collect the ethanol eluate and c...

Embodiment 2

[0095] (1) Take 18 parts of Hanshuishi, 18 parts of comfrey, 20 parts of Rehmannia glutinosa, 3 parts of Tumuxiang, 4 parts of artificial bezoar, 12 parts of gardenia, 15 parts of Chinese yam, 3 parts of Qumai, 3 parts of gypsum, and 3 parts of licorice;

[0096] (2) Grind artificial bezoar and cold water stone separately, and pass through a 120-mesh sieve;

[0097] (3) Comfrey add 7 times the amount of 80% ethanol for reflux extraction twice, the first time is 3 hours, the second time is 1 hour, filter, combine the filtrate, recover the ethanol until the extract contains 0.3g / ml crude drug, filter Over, add this ethanol extract to the AB-8 type macroporous adsorption resin column for adsorption at a flow rate of 4BV / h, let stand for 6 hours, then wash with an aqueous solution of 8 times the column volume at a flow rate of 5BV / h, and then use 70% ethanol solution was eluted at a flow rate of 3BV / h, and the ethanol elution multiple was 7 times. The ethanol eluate was collected ...

Embodiment 3

[0103] (1) Take 18 parts of Hanshuishi, 18 parts of comfrey, 20 parts of Rehmannia glutinosa, 3 parts of Tumuxiang, 4 parts of artificial bezoar, 12 parts of gardenia, 15 parts of Chinese yam, 3 parts of Qumai, 3 parts of gypsum, and 3 parts of licorice;

[0104](2) Grind artificial bezoar and cold water stone separately, and pass through a 120-mesh sieve;

[0105] (3) Comfrey add 8 times the amount of 80% ethanol to reflux extraction twice, the first time is 3 hours, the second time is 3 hours, filter, combine the filtrate, recover the ethanol until the extract contains 0.5g / ml crude drug, filter After that, the alcohol extract was added to the macroporous adsorption resin column for adsorption at a flow rate of 5BV / h, left to stand for 6 hours, then washed with an aqueous solution of 10 times the column volume at a flow rate of 6BV / h, and then washed with 70% ethanol solution Elute at a flow rate of 4BV / h, and the ethanol elution multiple is 10 times. Collect the ethanol elu...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hypertension, high blood fat, high blood sugar and high blood viscosity and a preparation method thereof. The traditional Chinese medicine composition improves the traditional Mongolian medicine serum eight-ingredient tablets and is characterized in that the traditional Chinese medicine composition is prepared from 10to 20 parts by weight of gypsum rubrum, 10 to 20 parts by weight of radix lithospermi, 10 to 25 parts by weight of prepared rehmannia root, 1 to 5 parts by weight of scabwort, 1 to 8 parts by weight of artificial bezoar, 4 to 15 parts by weight of jasmine, 8 to 15 parts by weight of Chinese yam, 1 to 5 parts by weight of fringed pink, 1 to 5 parts by weight of gypsum and 1 to 5 parts by weight oflicorice root. A part of the raw material medicines are subjected to water extraction and alcohol precipitation, a part of the raw material medicines are extracted through alcohol, the extract is refined by macroporous resin and the improved product has good effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating hypertension, hyperlipidemia, hyperglycemia and hyperviscosity and a preparation method thereof. Background technique [0002] The three highs are the general term for hyperlipidemia, hypertension, and hyperglycemia. Studies have shown that the aggregation of these three clinical diseases is not accidental. In 1988, Reaven, a famous American endocrinologist, collectively referred to insulin resistance in hyperglycemia, hyperinsulinemia, abnormal glucose tolerance, hypertriglyceridemia in hyperlipidemia, and hypertension as "X syndrome", which is now commonly used in medical circles. Said metabolic syndrome. Hyperviscosity is one of the more common syndromes of abnormal blood viscosity. The main clinical manifestations are dizziness, headache, vertigo, tinnitus, numbness of limbs, chest tightness and p...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/30A61P9/12A61P3/06A61P3/10A61P9/00A61K35/413A61K33/06
CPCA61K9/2059A61K9/282A61K33/06A61K35/413A61K36/28A61K36/30A61K36/36A61K36/484A61K36/744A61K36/804A61K36/8945A61K2236/33A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 叶瀚骏
Owner 内蒙古蒙奇药业有限公司
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