Propolis lozenge and preparation method thereof

A technology of propolis and propolis alcohol, which is applied in the direction of medical preparations containing active ingredients, medical formulas, and medical preparations with no active ingredients, etc., can solve problems such as not being suitable for long-term use, and achieve technological progress, good economic benefits, and good The effect of social effects

Inactive Publication Date: 2018-06-15
浙江金童生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, most throat-clearing products on the market are medicines, the most common ones are medicines made of traditional Chinese medicine, such as lozenges made of grass coral, lozenges made of golden camellia, etc. These kinds of medicines are not suitable for long-term use, and there is an urgent need for a Healthy Alternative Products

Method used

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  • Propolis lozenge and preparation method thereof

Examples

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preparation example Construction

[0041] refer to figure 1 , the present invention also provides a kind of preparation method of propolis lozenge, comprises the following steps:

[0042] (1) Inclusion: Take an appropriate amount of ethanol solution, add an appropriate amount of propolis alcohol extract, stir and dissolve to form a certain concentration of propolis alcohol extract ethanol solution, fully dissolve and filter through a 300-mesh sieve for later use;

[0043]Take an appropriate amount of aqueous solution, add an appropriate amount of inclusion agent, and prepare an aqueous solution of inclusion agent with a certain concentration, and set it aside;

[0044] Add the prepared ethanol solution of propolis alcohol extract into the aqueous solution of inclusion agent while stirring, and stir until it is fully dispersed and free of suspended matter, so as to obtain the inclusion solution;

[0045] (2) Filtration and drying: filter the clathrate solution through a filter membrane to remove the solvent, ta...

Embodiment 1

[0058] The invention provides a propolis buccal tablet, which is mainly made of the following raw materials in parts by weight: 20 parts of propolis alcohol extract, 40 parts of beta-cyclodextrin, 200 parts of sugar powder, 10 parts of sodium carboxymethylcellulose, 3 parts of menthol, 3 parts of peppermint oil, 4 parts of magnesium stearate, 10 parts of gastric-soluble film coating premix.

[0059] The preparation method of above-mentioned a kind of propolis buccal tablet, comprises the following steps:

[0060] (1) Inclusion: Take 60%-95% concentration of ethanol solution, add 20 parts of propolis alcohol extract, stir and dissolve into 10%-50% concentration of propolis alcohol extract ethanol solution, fully dissolve and pass through a 300-mesh sieve Net for filtering, standby;

[0061] Take an appropriate amount of drinking water or purified water, heat it to 40°C-80°C, add 40 parts of beta-cyclodextrin to prepare an aqueous solution of beta-cyclodextrin inclusion agent w...

Embodiment 2

[0072] The difference from Example 1 is that 300 parts of mannitol and 14 parts of povidone K30 are added in the mixing link in step (4) of the preparation method.

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Abstract

The invention discloses a propolis lozenge. The propolis lozenge is characterized in that the propolis lozenge is mainly prepared from, by weight, 10-50 parts of propolis alcohol extract, 25-100 partsof an inclusion agent, 100-500 parts of powdered sugar, 12-20 parts of a thickener, 4-20 parts of a flavoring agent, 2-8 parts of the a lubricating and anti-sticking agent and 5-20 parts of a film coating premix. The invention also discloses a preparation method of the propolis lozenge. The method comprises the following steps: inclusion, filtration, drying, crushing, mixing, granulation, tabletting and coating. The propolis lozenge is a throat heat clearing product produced by using the antibacterial and anti-inflammatory properties of propolis (the propolis contains a large amount of totalflavonoids), and is mainly suitable for people with throat discomfort.

Description

technical field [0001] The invention relates to a propolis buccal tablet and a preparation method thereof. Background technique [0002] According to doctor trained in Western medicine, pharyngitis can be divided into acute pharyngitis and chronic pharyngitis. Acute pharyngitis is often caused by viruses or bacteria. Virus infection is transmitted through droplets and close contact, mainly caused by Coxsackie virus, adenovirus, and parainfluenza virus. Bacterial infections were mainly streptococcus, staphylococcus and pneumococcus. Chronic pharyngitis is mainly due to incomplete treatment of acute pharyngitis and repeated attacks, which become chronic, or because of various nasal diseases, nasal orifice blockage, long-term mouth breathing, and physical, chemical factors, neck radiation therapy and other frequent stimulation. Caused by the pharynx. Hazards: Pharynx causes coughing, wheezing, etc., causing respiratory diseases; affecting food swallowing, diaphragm spasm, hi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/644A61K47/69A61K9/30A61P11/04
Inventor 童建华李正亮
Owner 浙江金童生物科技有限公司
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