System and kit for predicting adverse events after myocardial infarction

A technology for adverse events and detection components, applied in the field of medical diagnosis, can solve problems such as difficult to standardize the assessment of long-term adverse event risks, large differences in training, and no risk assessment of adverse events in patients with acute myocardial infarction

Active Publication Date: 2018-07-10
北京豪思生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The problems of this detection method include: the medical level varies greatly in different regions, and the relevant training received by doctors of different levels varies greatly. First, it is difficult to standardize the assessment of the risk of long-term adverse events after myocardial infarction, so as to control the follow-up treatment; second, Simply stratifying the risk of adverse events based on age, gender, and w...

Method used

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  • System and kit for predicting adverse events after myocardial infarction
  • System and kit for predicting adverse events after myocardial infarction
  • System and kit for predicting adverse events after myocardial infarction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0117] Example 1 Thyroid-stimulating hormone detection reagent detects adverse events after myocardial infarction

[0118] After the patient confirmed acute myocardial infarction, 2ml of serum was extracted immediately, and the thyroid-stimulating hormone level of the sample was calculated according to the aforementioned thyroid-stimulating hormone detection method of this patent.

[0119] In the patient association study on possible adverse events after myocardial infarction, it was shown that the risk of adverse events after myocardial infarction was detected only by the thyroid-stimulating hormone level reagent of the present invention, without using the definition tools of blood pressure detection tools and medical history inquiry tools , when the detection value of thyroid-stimulating hormone level is 10.0IU / L, the correlation between the detected value and the risk of adverse events after myocardial infarction increased by 3.57 times. Obtain the receiver operating charac...

Embodiment 2

[0120] Example 2 Combined detection of thyroid-stimulating hormone and free triiodothyronine adverse events after myocardial infarction

[0121] The method for measuring the thyroid-stimulating hormone level by the patient's thyroid-stimulating hormone reagent is the same as that in Example 1. At the same time, 2ml of serum was extracted, and the free triiodothyronine concentration of the sample was measured according to the aforementioned free triiodothyronine detection method of this patent.

[0122] In the study on the association of patients with possible adverse events after myocardial infarction, it was shown that only through the combination reagent for detection of thyroid-stimulating hormone level and free triiodothyronine of the present invention, without using the definitions of blood pressure detection tools and medical history inquiry tools The tool detects the risk of adverse events after myocardial infarction. When the detection value of thyroid-stimulating horm...

Embodiment 3

[0123] Example 3 Thyroid-stimulating hormone, free triiodothyronine detection reagent and diabetes history detection tool combined detection of risk of adverse events after myocardial infarction

[0124] The method for measuring thyroid-stimulating hormone level and free triiodothyronine with the combined reagent of thyroid-stimulating hormone and leukocytes in patients is the same as in Example 1, and the history of diabetes is confirmed: those who have been clearly diagnosed with diabetes or received diabetes drug treatment; fasting blood glucose after admission ≥ 7.0mmol / L (126mg / dl) or any blood sugar ≥ 11.1mmol / L (200mg / dl).

[0125] In the study on the correlation of patients with possible adverse events after myocardial infarction, it was shown that the detection of thyroid-stimulating hormone levels, free triiodothyronine combined reagents and diabetes history detection tools of the present invention, without using blood pressure detection tools, has a positive effect ...

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Abstract

The invention relates to the field of medical diagnosis, and in particular, relates to a system for predicting risks of adverse events (including a composite endpoint of death, re-infarction, heart failure and target vascular reconstruction) after myocardial infarction. The system includes an access controller, a detection part, a sample information receiving functional module, an assignment module, a risk calculation module and a reporting system main interface; the risk calculation module receives assignment values of the assignment module and calculates to obtain the risk of the adverse events after myocardial infarction according to the total score of the assignment values. The system is easy to operate, the results of the evaluation are intuitionistic to display, and the system provided by the invention can accurately and quickly do reasonable risk detection on the patient crowd with myocardial infarction, guides an individualized precise treatment strategy and has important clinical application value.

Description

technical field [0001] The invention relates to the field of medical diagnosis, in particular to a system and kit for predicting adverse events after myocardial infarction. Background technique [0002] At present, cardiovascular disease has become one of the most important diseases threatening human life. According to the World Health Organization, about 17 million people die from cardiovascular diseases every year, accounting for one-third of the global death toll. It is estimated that by 2020, this number may exceed 20 million. A survey and analysis of the causes of death in my country shows that in recent years, cardiovascular and cerebrovascular diseases accounted for 40% of the death toll in my country. It has become the number one killer that endangers the health of Chinese people and has caused a huge burden to society and families. [0003] Acute myocardial infarction (AMI) is one of the leading causes of cardiovascular death. With the application of intensive dru...

Claims

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Application Information

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IPC IPC(8): G01N33/78G01N33/66G01N35/00
CPCG01N33/66G01N33/78G01N35/00584
Inventor 唐熠达王文尧田间祁雨
Owner 北京豪思生物科技股份有限公司
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