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A kind of Yao medicine antipyretic patch and preparation method thereof
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A technology of antipyretic patch and Yao medicine, which is applied in the direction of medical formula, antipyretic, drug combination, etc., can solve the problems of delayed treatment timing, slow onset of antipyretic patch, etc., achieve short action time, low cost, and large amount of medicinal materials Effect
Active Publication Date: 2021-03-26
GUANGXI UNIV OF CHINESE MEDICINE
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Problems solved by technology
However, most antipyretic plasters on the market take effect slowly, often delaying the timing of treatment
Method used
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Embodiment 1
[0020] The preparation of embodiment 1 Yaoyao antipyretic plaster
[0021] Follow the steps below:
[0022] (1) Extraction of Yao medicinal materials: take 20 parts of ginger, 15 parts of peppermint, 15 parts of jiubing, 10 parts of Artemisia annua, 4 parts of Digupi in parts by weight, crush them, soak in 50% ethanol solution for 3 hours, soak 3 times , combined the leachate, concentrated under reduced pressure, clarified, decolorized, applied AB-8 macroporous adsorption resin, eluted with 60% ethanol, concentrated the eluate under reduced pressure, dried, and obtained the Yao medicine extract with a yield of 70%;
[0023] (2) Preparation of Yaoyao Antipyretic Patch: Dissolve the Yaoyao extract in step (1) in silica sol, stir evenly, adjust the pH to 9 with lye, form Yaoyao gel, pour it into a mold, put Freeze at 4°C for 48 hours in the refrigerator to prepare the Yaoyao Antipyretic Patch.
Embodiment 2
[0024] Preparation of Example 2 Yaoyao Antipyretic Patch
[0025] Follow the steps below:
[0026] (1) Extraction of Yao medicinal materials: take 17 parts of ginger, 12 parts of peppermint, 12 parts of jiubing, 7 parts of Artemisia annua, and 3 parts of Digupi in parts by weight, grind them, soak in 35% ethanol solution for 3 hours, and soak for 3 times , combine the leachate, concentrate under reduced pressure, clarify, decolorize, apply X-5 macroporous adsorption resin, elute with 50% ethanol, concentrate the eluate under reduced pressure, dry, and obtain the Yao medicine extract with a yield of 91%;
[0027] (2) Preparation of Yaoyao Antipyretic Patch: Dissolve the Yaoyao extract in step (1) in silica sol, stir evenly, adjust the pH to 8 with lye, form Yaoyao gel, pour it into a mold, put Freeze at 4°C for 24 hours in the refrigerator to prepare the Yaoyao Antipyretic Patch.
Embodiment 3
[0028] Preparation of Example 3 Yaoyao Antipyretic Patch
[0029] Follow the steps below:
[0030] (1) Extraction of Yao medicinal materials: take 15 parts of ginger, 10 parts of peppermint, 10 parts of jiubing, 5 parts of Artemisia annua, 2 parts of Digupi in parts by weight, pulverize, soak in 30% ethanol solution for 3 hours, soak 3 times , combine the leachate, concentrate under reduced pressure, clarify, decolorize, apply X-5 macroporous adsorption resin, elute with 40% ethanol, concentrate the eluent under reduced pressure, dry, and obtain the Yao medicine extract with a yield of 65%;
[0031] (2) Preparation of Yaoyao Antipyretic Patch: Dissolve the Yaoyao extract in step (1) in silica sol, stir evenly, adjust the pH to 8 with lye, form Yaoyao gel, pour it into a mold, put Freeze at 4°C for 48 hours in the refrigerator to prepare the Yaoyao Antipyretic Patch.
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Abstract
The invention provides a Yao medicine fever cooling paste and a preparation method thereof. The preparation method comprises the following steps: (1) extraction of Yao medicinal materials: gingers, mints, barks of ovateleaf holly, sweet wormwood, and Chinese wolfberry roots and barks are taken and crushed, immersion with an ethanol solution is carried out for 3 hours with 1-3 times, percolate is merged, vacuum concentration, clarification and decolouring are carried out, an AB-8 macroporous adsorption resin is used, elution is carried out with ethanol, vacuum concentration is carried out withan eluant, drying is carried out, in order to obtain a Yao medicine extract product; (2) preparation of the Yao medicine fever cooling paste: the Yao medicine extract product in the step (1) is dissolved in sol with uniform stirring, alkali lye is used for adjusting pH, in order to form Yao medicine gel, the gel is poured into a die, the die is placed in a refrigerator for solidification and fixing, and the Yao medicine fever cooling paste is prepared. The Yao medicine extract product is prepared into a hydrogel dosage form, which is applied to a plaster, in order to greatly perform efficaciesof the composition, facilitate absorption for patients, and realize good fever cooling treatment effects.
Description
technical field [0001] The invention relates to the technical field of antipyretic plasters, in particular to a Yao medicine antipyretic plaster. Background technique [0002] Fever, also known as fever in medical terms, refers to a body temperature that exceeds the upper limit of the normal range. It is a very common symptom in children. Fever supports the immune system in fighting infectious agents and keeps temperature-sensitive viruses and bacteria from replicating well in the body. However, infection is not the only cause of fever. For example, amphetamine abuse and alcohol withdrawal symptoms can both lead to elevated body temperature. Environmental stress can also cause heat stroke and related illnesses. Sometimes, a fever can be so severe that it affects your health. For example, a fever over 105 degrees Fahrenheit can threaten the integrity and function of important proteins. Cellular stress, infarction (heart attack), tissue necrosis, convulsions, and delirium...
Claims
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