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Use of Nocadia rubra cell wall skeleton in preparation of medicine/skincare product for treating acnes, and medicine/skin care composition

A Nocardia rubrum, cell wall technology, applied in drug combinations, cosmetic preparations, cosmetic preparations, etc., can solve problems such as allergies, adverse side effects, irritation, etc., and achieve good safety effects

Pending Publication Date: 2018-07-20
FUJIAN SHANHE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, salicylic acid can maintain an ideal solubility only at pH3-4, so salicylic acid preparations have adverse side effects, which can cause dry skin, irritation and allergies, etc.

Method used

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  • Use of Nocadia rubra cell wall skeleton in preparation of medicine/skincare product for treating acnes, and medicine/skin care composition
  • Use of Nocadia rubra cell wall skeleton in preparation of medicine/skincare product for treating acnes, and medicine/skin care composition
  • Use of Nocadia rubra cell wall skeleton in preparation of medicine/skincare product for treating acnes, and medicine/skin care composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The skin care product composition is prepared by the following steps: firstly mix the Nocardia rubra cell wall skeleton, benzoic acid, sodium sulfite, glycerin, lanolin, squalene and part of distilled water uniformly, using 1% (w / v) hydrogen The pH of the sodium oxide solution was adjusted to 7, and the remaining distilled water was added. The amount of the above-mentioned materials was such that the mixture contained 0.01% by weight of Nocardia rubra cell wall skeleton, 0.1% by weight of benzoic acid, and 0.2% by weight of sodium sulfite , 5 wt% glycerin, 4 wt% lanolin, 0.2 wt% squalene. The above mixture was stirred at a rate of 50 revolutions per minute for 10 minutes to prepare a 0.01% by weight Nocardia rubra cell wall skeleton skin care emulsion.

Embodiment 2

[0052] The skin care product composition is prepared by the following steps: firstly mix the Nocardia rubra cell wall skeleton, benzoic acid, sodium sulfite, carbomer, glycerin, ethanol and part of distilled water uniformly, and use 1% (w / v) hydroxide The pH of the sodium solution was adjusted to 7, and the remaining distilled water was added. The amount of the above-mentioned materials was such that the mixture contained 0.1% by weight of Nocardia rubra cell wall skeleton, 0.1% by weight of benzoic acid, 0.2% by weight of sodium sulfite, 1.5% by weight carbomer, 5% by weight glycerin, and 20% by weight ethanol. The above mixture was stirred at a rate of 50 revolutions per minute for 10 minutes to prepare a 0.1% by weight Nocardia rubra cell wall skeleton skin care essence.

Embodiment 3

[0054] The skin care product composition is prepared by the following steps: firstly mix the Nocardia rubra cell wall skeleton, benzoic acid, sodium sulfite, lanolin, squalene, polysorbate and part of distilled water uniformly, using 1% (w / v) Adjust the pH of the sodium hydroxide solution to 7, and add the remaining distilled water. The amount of the above-mentioned materials is such that the mixture contains 0.3% by weight of Nocardia rubra cell wall skeleton, 0.1% by weight of benzoic acid, and 0.2% by weight % Sodium sulfite, 10% by weight lanolin, 0.2% by weight squalene, 15% by weight polysorbate. The above mixture was stirred at a rate of 20 revolutions per minute for 10 minutes to prepare a 0.3% by weight Nocardia rubra cell wall skeletal cream.

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PUM

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Abstract

The invention discloses a use of a Nocadia rubra cell wall skeleton in the preparation of a medicine / skincare product for treating acnes, and provides a medicine / skin care composition containing the Nocadia rubra cell wall skeleton and used for treating acnes. The Nocadia rubra cell wall skeleton is applied to acne treatment, can effectively treat various clinic symptoms of the acnes, comprising comedones, whitehead acnes, inflammatory papules, pustules, tubercles, tumors and acne induced marks, has good safety, and has no irritation effect on skins.

Description

Technical field [0001] The present invention relates to the fields of medicines and skin care products, in particular to the use of Nocardia rubra cell wall skeleton in the preparation of acne treatment medicine / skin care products and the medicine / skin care product composition. Background technique [0002] Acne, commonly known as pimples, acne, and acne, is a chronic skin disease that occurs in the sebaceous glands of hair follicles. According to statistics, 95% of adolescent men and 85% of adolescent women suffer from acne of varying degrees. The main clinical manifestations of acne are blackheads, whiteheads, inflammatory papules, pustules, nodules, cysts, which are prone to hyperpigmentation, enlarged pores and even scar-like lesions, which mostly occur on the head, face, neck, chest and back In areas with abundant sebaceous glands, severe acne can cause disfigurement. [0003] At present, most active ingredients of acne treatment agents are salicylic acid. Salicylic acid is a...

Claims

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Application Information

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IPC IPC(8): A61K35/74A61K8/99A61Q19/00A61P17/10
CPCA61Q19/00A61K8/99A61K35/74A61P17/10
Inventor 徐镜王骥飞李戈
Owner FUJIAN SHANHE PHARMA
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