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Application of Aronia melanocarpa Elliot anthocyanin in preparation of anti-liver fibrosis drugs or health care products

The invention relates to a technology for anti-liver fibrosis of Aronia nigra, applied in the fields of health food and medicine, and can solve the problems of affecting endocrine function and digestive tract reaction, strong side effects, high toxicity, etc., and achieves complete and clear liver tissue structure. Strong antioxidant activity, non-denaturing effect

Inactive Publication Date: 2018-07-24
LIAONING UNIVERSITY
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

However, chemically synthesized drugs have high cost, high toxicity, and strong side effects, which will affect side effects such as endocrine function and gastrointestinal reactions.

Method used

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  • Application of Aronia melanocarpa Elliot anthocyanin in preparation of anti-liver fibrosis drugs or health care products
  • Application of Aronia melanocarpa Elliot anthocyanin in preparation of anti-liver fibrosis drugs or health care products
  • Application of Aronia melanocarpa Elliot anthocyanin in preparation of anti-liver fibrosis drugs or health care products

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Experimental program
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Embodiment 1

[0018] (1) Preparation method

[0019] Preparation of Aronia anthocyanin extract: Weigh 100 g of Aronia fruit, soak it in 60% ethanol at 60-70°C for 1 hour, put it into an ultrasonic cleaner for 30 minutes, and do so twice in a row. After being purified by the macroporous adsorption resin AB-8, the extract is concentrated by a rotary evaporator, and vacuum freeze-dried to obtain dry Aronia anthocyanin powder.

[0020] After testing, the anthocyanin dry powder mainly contains 47.6% cyanidin 3-arabinoside and 46.4% cyanidin 3-galactoside.

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Abstract

The invention relates to application of Aronia melanocarpa Elliot anthocyanin in preparation of anti-liver fibrosis drugs or health care products. Aronia melanocarpa Elliot anthocyanin can be used singly or in combination with other drugs with anti-liver fibrosis effect, and can be prepared into any dosage form drugs or health care products suitable for oral taking according to the preparation method of conventional preparations. Aronia melanocarpa Elliot anthocyanin has very strong liver fibrosis preventing ability.

Description

technical field [0001] The invention belongs to the field of health food and medicine, and in particular relates to the application of Aronia adenocarpus anthocyanins in the preparation of medicines or health products for treating and preventing liver fibrosis. Background technique [0002] Hepatic fibrosis (fibrosis of liver) is a pathological change caused by chronic liver damage caused by various reasons. necessary stage. It is now believed that liver fibrosis may be reversed to normal, while liver cirrhosis is not. The current research focuses on the interaction between molecule and molecule, molecule and cell and cell and cell. Although there has been some progress in diagnosis and treatment, there is still a lack of definitive and effective drugs. [0003] Liver fibrosis health products can prevent liver fibrosis to a certain extent, promote health and reduce liver damage. At present, anti-hepatic fibrosis drugs can be divided into two categories: traditional Chine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P1/16A23L33/105A61K131/00
CPCA23V2002/00A61K36/73A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A23L33/105A23V2200/32A23V2250/21
Inventor 魏杰高军范俊岗杨静
Owner LIAONING UNIVERSITY
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