Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Compositions and methods using a polyphenol for musculoskeletal health

A composition and muscle technology, applied in the fields of preventing sarcopenia or slowing down the progress of sarcopenia, treatment, and recovery of muscle function, can solve problems such as difficult prevention or treatment measures, and achieve the effect of promoting relief and slowing down the development

Pending Publication Date: 2018-07-31
SOC DES PROD NESTLE SA
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the etiology and pathophysiology of sarcopenia remain poorly understood, making effective preventive or therapeutic measures difficult

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Compositions and methods using a polyphenol for musculoskeletal health
  • Compositions and methods using a polyphenol for musculoskeletal health
  • Compositions and methods using a polyphenol for musculoskeletal health

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0089] The following non-limiting examples provide scientific data for the development and support of the following concepts: administration of a composition containing one or more polyphenols to treat sarcopenia, prevent sarcopenia, Reduce the loss of muscle function (such as muscle strength, walking speed, etc.), enhance muscle function (such as muscle strength, walking speed, etc.), and / or improve the recovery of muscle function (such as muscle strength, walking speed, etc.).

[0090] The murine C2C12 myoblast cell line (satellite cells derived from the thigh muscle) can well show muscle atrophy and hypertrophy. C2C12 cells differentiate in multinucleated myotubes. By measuring the activity of creatine kinase (CK) in C2C12 cells, the differentiation of myoblasts and subsequent myotube formation were observed biochemically.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A composition comprising one or more polyphenols, such as oleuropein, rutin, curcumin or quercetin, can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and / or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and / or frail.

Description

Background technique [0001] The present disclosure generally relates to compositions and methods that use one or more polyphenols to improve or maintain musculoskeletal health. More specifically, the present disclosure relates to administering a composition containing one or more polyphenols to treat, prevent or slow the progression of sarcopenia; reduce the loss of muscle function (such as muscle strength, walking speed, etc.); Enhance muscle function, and / or improve the recovery of muscle function after muscle atrophy or injury. [0002] Muscle loss is manifested in several life-threatening diseases, including sarcopenia. The balance between atrophy (loss) and hypertrophy (increase) is the key to maintaining skeletal muscle mass. However, skeletal muscle is terminally differentiated, so understanding the mechanisms that allow this plasticity is central to long-term health and survival. [0003] Sarcopenia is defined as age-related loss of muscle mass and function (including mus...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L29/00A61K31/05A61P21/06
CPCA61K31/12A61K31/7048A61K31/352A61K38/1709A61K38/011A61K31/202A61P21/00A23L33/105A23L33/12A23L33/185A23L33/19A23L33/125A23V2002/00A61K2300/00A23V2200/316A23V2250/187A23V2250/21A23V2250/2112A23V2250/54252A23V2250/54246A23V2250/548A61K38/00A61K45/06A23L33/40A23L33/17A61K31/353A61P21/06A61P43/00A23V2250/1868A23V2250/2116A23V2250/21168A23V2250/2117
Inventor M·N·奥卡亚达F·门布雷兹D·布勒耶C·布特里
Owner SOC DES PROD NESTLE SA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com