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Weight-losing application of apios americana flower ethanol extract

A technology of ethanol extraction and taro flower, applied in the field of medicine, can solve the problem that the weight loss activity of the ethanol extract of taro flower is rarely reported, and achieves prevention of obesity and related chronic diseases, alleviation of weight gain, and remarkable effect. Effect

Inactive Publication Date: 2018-08-14
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, many nutrition and health food researchers are currently paying great attention to the research and topics related to the occurrence and prevention of obesity and chronic diseases, but there are few reports on the weight loss activity of the ethanol extract of taro flower

Method used

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  • Weight-losing application of apios americana flower ethanol extract
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  • Weight-losing application of apios americana flower ethanol extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1, the slimming purposes of soybean taro flower ethanol extract, such as Figure 1-Figure 5 It is shown that the ethanol extract of taro flower has a significant effect of weight loss and lipid reduction.

[0049] The specific preparation steps of soybean taro flower ethanol extract are as follows:

[0050] (1) After mixing the taro flower with ethanol containing 0.1mol / L hydrochloric acid according to the ratio of material to liquid of 1g:10ml, it is processed and beaten by a juicer. The obtained slurry was subjected to ultrasonic leaching for 90 minutes at 45° C., the extract was centrifuged at 3000 g for 30 minutes, and the extract was centrifuged to obtain a supernatant.

[0051] (2), replace the bean taro flower in the step (1) with the filter residue obtained by centrifugation in the step (1), repeat the extraction 2 times, combine the three filtrates, and concentrate by rotary evaporation to obtain a concentrated solution (concentrated to 15% of the o...

Embodiment 2

[0063] Embodiment 2, the effect of ethanolic extract of soybean taro flower on organ indexes such as fat and liver in obese mice;

[0064] The mice in Example 1 were fasted for 24 hours after gavage for 12 weeks, and their body weights were weighed. After blood was collected from the orbit, the mice were sacrificed by cervical dislocation, and the fat around the kidney and the epididymis was collected, and the heart, liver, spleen, and kidney were quickly extracted. , brown fat and other tissues and record the weight, the specific data are shown in Table 1.

[0065] Table 1 The effect of ethanol extract of soybean taro flower on the organ index of mice

[0066]

[0067] According to Table 1, different doses of taro ethanol extract can significantly reduce the peritesticular fat and perirenal fat index in obese mice. , heart, kidney, spleen and pancreas indices were not significantly affected. The above results indicated that the ethanolic extract of soybean taro flower co...

Embodiment 3

[0068] Embodiment 3, the effect of ethanol extract of soybean taro flower on serum triglyceride (TG), total cholesterol (TC), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) content in obese mice;

[0069] The mice in Example 1 were fasted for 24 hours after gavage for 12 weeks, and the mice were sacrificed by cervical dislocation after the orbital blood was collected. Triester and total cholesterol content were determined, and the specific data are shown in Table 2.

[0070] Table 2 The effect of ethanol extract of soybean taro flower on the serum indexes of mice

[0071]

[0072] According to Table 2, the intervention of high-dose ethanol extract of taro flower can reduce the total cholesterol content in serum of obese mice induced by high-fat diet, and both high-dose and low-dose groups can significantly reduce serum triglyceride in obese mice. Ester, alanine aminotransferase, aspartate aminotransferase content. The above results showed that the eth...

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Abstract

The invention discloses weight-losing application of a apios americana flower ethanol extract and provides novel resources for developing natural weight-losing products in the fields of medicine, foodsciences and the like. According to the weight-losing application disclosed by the invention, proved by an experiment of inducing obese mice by high fat diet, the apios americana flower ethanol extract has the advantages that body weight of the obese mice can be remarkably reduced, the contents of triglyceride and total cholesterol in serum and liver are reduced, and the effects are comprehensiveand obvious. Therefore, the apios americana flower ethanol extract disclosed by the invention is applied to prepare weight-losing food or drugs so as to treat and prevent obesity and associated chronic diseases thereof.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a weight loss application of ethanol extract of taro flower. Background technique [0002] Bean taro (Apios americana Medikus) is native to Canada in the eastern part of North America to the southern part of Florida, and belongs to the perennial legume (Pterophyceae subfamily). Its edible parts are underground tubers, and its protein content is higher than that of other plant tubers. It is a crop with both nutrition and economic value, so it is often used as a staple food by Indians. Bean taro has been successfully introduced in China since 2009, and has been gradually promoted and cultivated in Fuyang, Jinhua, Longyou, Wenzhou and other places. Studies have shown that different parts of soybean taro (flowers, vines, leaves, tubers) are rich in free amino acids, soluble proteins, polysaccharides, saponins, flavonoids, isoflavones, vitamin C, vitamin E and minerals. Among them, taro flow...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P3/04A23L33/105A61K133/00
CPCA61K36/48A23L33/105A23V2002/00A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61P3/04A23V2200/332A23V2250/21
Inventor 郑晓冬楚强俞露霜陈鹏华刘阳阳李永璐
Owner ZHEJIANG UNIV
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