Praziquantel pill for veterinary use and preparation method of praziquantel pill

Abstract

The invention discloses a praziquantel pill for veterinary use and a preparation method of the praziquantel pill. The praziquantel pill is prepared from the following raw materials by weight percent:2.5 to 15 percent of praziquantel, 81.5 to 91.5 percent of basic nutrition powder, 1 to 5 percent of disintegrating agent, 0.05 to 1 percent of flavor enhancer, 0.02 to 0.2 percent of preservative, 0.02 to 0.2 percent of antioxidant, and 2 to 8 percent of medicinal starch or / and hydroxypropyl methylcellulose; and the basic nutrition powder is prepared from cereal, meat, bone powder, corn protein powder, vegetable oil, animal grease, table salt, vitamins and minerals. The praziquantel bill has a high attractant effect, and is unlikely to disintegrate, particularly suitable for being widely dispensed in the field or for manually feeding canidae host animals with an infection source at a fixed point, convenient for feeding the livestock, complete in basic nutrition, and capable of preventingand treating parasitic infection of the animal such as schistosomiasis, teniasis and cysticercosis.

Description

technical field [0001] The invention relates to the technical field of veterinary medicine, in particular to a veterinary praziquantel pill and a preparation method thereof. Background technique [0002] Hydatid disease is a zoonotic parasitic disease caused by Echinococcus tapeworms parasitizing in humans or host animals. In my country, there are two types of echinococcosis: cystic echinococcosis and alveolar echinococcosis. Among them, alveolar echinococcosis is called "worm cancer" because of its high fatality rate. Echinococcosis is mainly prevalent in pastoral and semi-agricultural and semi-pastoral areas in western China, especially in Xinjiang, Qinghai, Gansu, Ningxia, Tibet, Inner Mongolia and western Sichuan. The results of the national survey of important human parasitic diseases completed in 2004 showed that the average prevalence rate of echinococcosis in endemic areas was 1.084%. Based on this calculation, there are 380,000 echinococcosis patients in endemic a...

AI Technical Summary

Problems solved by technology

The commercially available praziquantel tablets recorded in the Chinese Pharmacopoeia and the Chinese Veterinary Pharmacopoeia have no food-attracting effect, and domestic dogs can be fed with bait for prevention and control, but for host animals with infectious sources, wild dogs, wild animals such as foxes and wolves, etc. It is impossible to realize large-area bait encapsulation and feeding, which increases the difficulty of the prevention and control of echinococcosis in endemic areas in my country

In addition, ordinary praziquantel tablets are easy to absorb water and collapse when exposed to rain or wrapped in wet bait. In the complex environment in the wild, the drug loss is serious.

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