Preparation method of gelatin filled silk protein gelatin gel fiber membrane

Abstract

The invention provides a preparation method of a gelatin filled silk protein gelatin gel fiber membrane. The preparation method comprises the following steps: under a nitrogen gas environment, takingacrylamide as a monomer and water as a solvent, and taking potassium persulfate and sodium sulfite as an oxidization reduction initiator; dividing the oxidization reduction initiator into three equalparts; adding the first part of the initiator into a water solution of the acrylamide; firstly, carrying out low-temperature polymerization reaction; adding the second part of the initiator and continually reacting; adding rabbit skin gelatin particle sponge and the third part of the initiator; reacting again; dropwise adding hydroquinone to obtain a polyacrylamide modified gelatin solution; dissolving a silk protein nano-fiber membrane into a formic acid solution; adding the rabbit skin gelatin particle sponge and uniformly mixing to obtain a spinning solution; carrying out electrostatic spinning to obtain the silk protein gelatin gel nanofiber membrane; immersing the silk protein gelatin gel nanofiber membrane into the polyacrylamide modified gelatin solution; dropwise adding glutaraldehyde and carrying out microwave oscillation treatment; taking out the fiber membrane and drying to obtain the gelatin filled silk protein gelatin gel fiber membrane.

Description

technical field [0001] The invention belongs to the technical field of textile materials, and in particular relates to a preparation method of a gelatin-filled silk protein gelatin gel fiber membrane. Background technique [0002] Gelatin is a natural polymer compound produced after the collagen of connective tissues such as animal skin, bone, sarcolemma, and tendon undergoes gentle and irreversible fracture. It is a thermoreversible mixture. During the transformation of collagen fibers, the triple helical structure After the three α-peptide chains are basically loosened, they form hydrogen bonds, irregularly folded α-peptide chains, γ-chains or β-chains, and gradually form the secondary structure or tertiary structure of gelatin molecules, and the imino acids contained in gelatin promote gelatin Peptide chains aggregate and cross-link in aqueous solution to form a three-dimensional ordered triple-helix network structure, and due to the structure and composition of the pyrro...

AI Technical Summary

Problems solved by technology

[0003] Fibers prepared from gelatin have good biocompatibility, film-forming properties and certain mechanical properties, and have good application prospects in the fields of biomedicine, textile materials and tissue functions, but the fiber-forming properties of gelatin fibers are poor , the fiber texture is brittle, easily soluble in hot water, and the stability and usability are poor, but by changing the composition of different amino acids in the gelatin source, or using the super hydrophilicity of gelatin and the high reactivity of the side chain group Physical and chemical cross-linking performed to improve the mechanical properties of gelatin fibers