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Composition with effects of tonifying kidney yang, enhancing immunity and relieving fatigue and preparation method and application thereof

A technology that enhances immunity and relieves fatigue. It is applied in the field of health food, which can solve the problems of hidden dangers of drug safety for consumers, increased complexity and cost of production, and achieve the effects of enhancing immunity, low cost, and short onset time

Inactive Publication Date: 2018-09-28
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many traditional Chinese medicine products that can improve immunity and invigorate the kidney and strengthen yang, but these products often contain 20 flavors or even more kinds of traditional Chinese medicine components. On the one hand, it brings hidden dangers to consumers, and on the other hand, it increases the complexity and cost of production. ; In addition, many traditional Chinese medicine ingredients can not bring more excellent efficacy to this kind of products

Method used

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  • Composition with effects of tonifying kidney yang, enhancing immunity and relieving fatigue and preparation method and application thereof
  • Composition with effects of tonifying kidney yang, enhancing immunity and relieving fatigue and preparation method and application thereof
  • Composition with effects of tonifying kidney yang, enhancing immunity and relieving fatigue and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1: preparation composition of the present invention

[0025] 40 parts of Astragalus membranaceus, 30 parts of Rehmannia glutinosa, 20 parts of Eucommia ulmoides, 10 parts of Morinda officinalis, 7.5 parts of medlar and 7.5 parts of sealwort (the weight ratio is 4:3:2:1:0.75:0.75), after mixing, add 12 times The weight of distilled water was boiled for 90 minutes, and the filtrate was taken; 10 times the weight of distilled water was added to the filter cake, and boiled for 60 minutes; the two filtrates were combined and filtered through 80 mesh; at a vacuum degree of -0.05MPa and a temperature of 70 ° C, vacuum concentration was obtained. Extract extract, wherein the soluble solid content is 25%. Refrigerate at 0°C for 12 hours, take out the 80-mesh filter, add purified water and a small amount of sucralose to taste and mix for 30 minutes to obtain a configuration solution with a soluble solid content of 11%, and remove the precipitate through a tubular centr...

Embodiment 2

[0026] Embodiment 2: animal model test

[0027] 1. Test drugs

[0028] Embodiment 1 composition of the present invention;

[0029] 2. Dose setting

[0030] Immunity-enhancing, anti-fatigue experiments: Experimental animals were randomly divided into control group, model control group, low-dose, middle-dose, and high-dose groups of the composition of Example 1 (5 times, 10 times, and 20 times the recommended dose for humans, respectively) , 10 animals in each group.

[0031] Improve kidney-yang deficiency experiment: Experimental animals are randomly divided into control group, model control group, low-dose, middle-dose, high-dose groups (respectively 2.5 times, 5 times, 10 times of human recommended dose), each Group of 10 animals.

[0032] 3. Test animals

[0033] KM mice, SPF grade, certificate number: SCXK (Guangdong) 2008-0020 Yuejian certificate number 2008A003, purchased from the Experimental Animal Center of Guangzhou University of Traditional Chinese Medicine; SD ...

Embodiment 3

[0093] Embodiment 3: Crowd survey evaluation test

[0094] 1. Test content

[0095] The present embodiment carries out consumer retention test to embodiment 1 composition, tests two kinds of compositions to male immunity / fatigue (resistance is poor, dizzy, easy fatigue / weakness, drowsiness and inattention) and kidney yang Improvement of deficiency (soreness of the waist and knees, chills and fear of cold, cold limbs, frequent urination at night and loss of libido), including comparative analysis of onset of effect and comparative analysis of satisfaction

[0096] 2. Sample conditions

[0097] 30-60 years old, male

[0098] At least one symptom of low immunity (poor resistance, dizziness), two symptoms of fatigue (easy fatigue / weakness, drowsiness and concentration) and three symptoms of kidney yang deficiency (symptoms occur at least once a week or more)

[0099] Have used certain methods to improve physical symptoms, such as diet therapy / Chinese medicine / beauty / health prod...

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Abstract

The invention relates to the technical field of health foods, and discloses a composition with the effects of tonifying kidney yang, enhancing immunity and relieving fatigue. The composition is an aqueous extract containing radix astragali, dried rehmannia root, eucommia, radix moridae officinalls, fructus lycii and polygonatum kingianum. According to the composition, the six Chinese herbal medicine including radix astragali, dried rehmannia root, eucommia, radix moridae officinalls, fructus lycii and polygonatum kingianum serve as components, and the composition with the effects of tonifyingkidney yang, enhancing immunity and relieving fatigue is extracted through a decoction method. Due to the combined action of the Chinese herbal medicine components, the composition has better advantages than similar products, the number of varieties of the Chinese herbal medicines is small, safety hidden hazards of medicine taking are reduced, the process is simple and convenient, and the cost islow.

Description

technical field [0001] The invention relates to the technical field of health food, in particular to a composition with the functions of invigorating kidney yang, enhancing immunity and relieving fatigue, its preparation method and application. Background technique [0002] In today's high-intensity and fast-paced work life, more and more people are suffering from decreased immunity, fatigue and kidney yang deficiency due to factors such as psychological stress, physical fatigue, negative pessimism, unbalanced diet, lack of exercise and excessive antibacterial. The sub-health status has brought many impacts on daily life and work. [0003] Modern medicine believes that a network is formed between the neuroendocrine system and the immune system, and many studies have suggested that the hypothalamus is the hub of the network. Kidney deficiency is due to the abnormal expression of related substances that mediate the network balance function, which makes the neuroendocrine immun...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P13/12A61P37/04A61P39/00A23L33/105
CPCA23L33/105A23V2002/00A61K36/46A61K36/481A61K36/746A61K36/804A61K36/815A61K36/8969A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P13/12A61P37/04A61P39/00A61K2300/00A23V2200/30A23V2250/21A61K2236/00A61P37/00A61P43/00A61K36/64A61K36/88
Inventor 刘硕李文治马思遥
Owner INFINITUS (CHINA) CO LTD