Composition with effects of tonifying kidney yang, enhancing immunity and relieving fatigue and preparation method and application thereof
A technology that enhances immunity and relieves fatigue. It is applied in the field of health food, which can solve the problems of hidden dangers of drug safety for consumers, increased complexity and cost of production, and achieve the effects of enhancing immunity, low cost, and short onset time
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Embodiment 1
[0024] Embodiment 1: preparation composition of the present invention
[0025] 40 parts of Astragalus membranaceus, 30 parts of Rehmannia glutinosa, 20 parts of Eucommia ulmoides, 10 parts of Morinda officinalis, 7.5 parts of medlar and 7.5 parts of sealwort (the weight ratio is 4:3:2:1:0.75:0.75), after mixing, add 12 times The weight of distilled water was boiled for 90 minutes, and the filtrate was taken; 10 times the weight of distilled water was added to the filter cake, and boiled for 60 minutes; the two filtrates were combined and filtered through 80 mesh; at a vacuum degree of -0.05MPa and a temperature of 70 ° C, vacuum concentration was obtained. Extract extract, wherein the soluble solid content is 25%. Refrigerate at 0°C for 12 hours, take out the 80-mesh filter, add purified water and a small amount of sucralose to taste and mix for 30 minutes to obtain a configuration solution with a soluble solid content of 11%, and remove the precipitate through a tubular centr...
Embodiment 2
[0026] Embodiment 2: animal model test
[0027] 1. Test drugs
[0028] Embodiment 1 composition of the present invention;
[0029] 2. Dose setting
[0030] Immunity-enhancing, anti-fatigue experiments: Experimental animals were randomly divided into control group, model control group, low-dose, middle-dose, and high-dose groups of the composition of Example 1 (5 times, 10 times, and 20 times the recommended dose for humans, respectively) , 10 animals in each group.
[0031] Improve kidney-yang deficiency experiment: Experimental animals are randomly divided into control group, model control group, low-dose, middle-dose, high-dose groups (respectively 2.5 times, 5 times, 10 times of human recommended dose), each Group of 10 animals.
[0032] 3. Test animals
[0033] KM mice, SPF grade, certificate number: SCXK (Guangdong) 2008-0020 Yuejian certificate number 2008A003, purchased from the Experimental Animal Center of Guangzhou University of Traditional Chinese Medicine; SD ...
Embodiment 3
[0093] Embodiment 3: Crowd survey evaluation test
[0094] 1. Test content
[0095] The present embodiment carries out consumer retention test to embodiment 1 composition, tests two kinds of compositions to male immunity / fatigue (resistance is poor, dizzy, easy fatigue / weakness, drowsiness and inattention) and kidney yang Improvement of deficiency (soreness of the waist and knees, chills and fear of cold, cold limbs, frequent urination at night and loss of libido), including comparative analysis of onset of effect and comparative analysis of satisfaction
[0096] 2. Sample conditions
[0097] 30-60 years old, male
[0098] At least one symptom of low immunity (poor resistance, dizziness), two symptoms of fatigue (easy fatigue / weakness, drowsiness and concentration) and three symptoms of kidney yang deficiency (symptoms occur at least once a week or more)
[0099] Have used certain methods to improve physical symptoms, such as diet therapy / Chinese medicine / beauty / health prod...
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