Application of pharmaceutical composition to preparation of medicines for treating type 2 diabetes mellitus

A type 2 diabetes and drug technology, applied in the field of pharmaceutical composition in the preparation of drugs for the treatment of type 2 diabetes, can solve the problems of no type 2 diabetes, reduce insulin resistance, regulate glucose and lipid metabolism, and simplify medication Effect

Inactive Publication Date: 2018-10-09
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There is no report on the combination of Coptis chinen

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of pharmaceutical composition to preparation of medicines for treating type 2 diabetes mellitus
  • Application of pharmaceutical composition to preparation of medicines for treating type 2 diabetes mellitus
  • Application of pharmaceutical composition to preparation of medicines for treating type 2 diabetes mellitus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0025] Take 2 parts of Coptis chinensis and 1 part of Evodia rutaecarpa. Weigh each herbal flavor according to the amount, mix with sufficient amount of water, and decoct with low heat for more than 30 minutes. After collecting the decoction, decoct with water for 2 more times, and combine each decoction to obtain the decoction.

Embodiment 2

[0026] The preparation of embodiment 2 pharmaceutical compositions of the present invention

[0027] Get the decoction prepared in Example 1, after concentrating, add appropriate amount of starch and dextrin and mix evenly before granulating.

Embodiment 3

[0028] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0029] Take 2 parts of Coptis chinensis and 1 part of Evodia rutaecarpa. Weigh each herbal flavor according to the amount, mix with sufficient amount of water, and decoct with low heat for more than 30 minutes. After collecting the decoction, decoct with water for 2 times, combine each decoction, dry, add appropriate amount of dextrin and soluble starch to granulate, and press into tablets to obtain tablets.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides application of a pharmaceutical composition to preparation of medicines for treating type 2 diabetes mellitus, and the pharmaceutical composition is prepared from the followingraw materials by a weight ratio: 2-10 parts of rhizoma coptidis and 1-10 parts of fructus evodiae. The composition provided by the invention can effectively improve the levels of fasting plasma glucose (FPG), fasting insulin (FINS) and OGTT2h plasma glucose (OGTT2hPG) in patients with the type 2 diabetes mellitus, and does not have an adverse effect; therefore, a new choice is provided for clinical medication.

Description

technical field [0001] The invention relates to the application of a pharmaceutical composition in the preparation of medicine for treating type 2 diabetes. Background technique [0002] Diabetes mellitus is a chronic metabolic disorder with high morbidity and multiple etiologies. It is clinically divided into type 1 and type 2, with type 2 patients being the majority. Type 2 diabetes is characterized by peripheral insulin resistance. At the molecular level, it is manifested by the loss of signal transduction after insulin binds to insulin receptors, causing persistent hyperglycemia, resulting in increased oxidative stress, and various chronic complications. [0003] Since the etiology and pathogenesis of diabetes are not yet fully understood, there is still a lack of effective etiological treatments. Various types of anti-type 2 diabetes chemical drugs have been used in clinical treatment in the market, mainly including sulfonylureas, biguanides, glucosidase inhibitors, in...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/754A61P3/10A61P5/50
CPCA61K36/718A61K36/754A61K2300/00
Inventor 扈晓宇李艳歌
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap