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Method for constructing UPLC fingerprint of Callicarpa nudiflora medicinal material, and standard fingerprint

A standard fingerprint, naked flower purple pearl technology, applied in the field of drug analysis, can solve the problem of not being able to effectively reflect and control the overall quality of naked flower purple pearl medicinal materials

Active Publication Date: 2018-10-16
HAINAN JIUZHITANG PHARMACY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The construction method according to the present invention solves the problem that the overall quality of the naked flower purple pearl medicinal material cannot be effectively reflected and controlled in the component analysis of the naked flower purple pearl medicinal material, and makes up for the deficiency of the existing quality control technology

Method used

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  • Method for constructing UPLC fingerprint of Callicarpa nudiflora medicinal material, and standard fingerprint
  • Method for constructing UPLC fingerprint of Callicarpa nudiflora medicinal material, and standard fingerprint
  • Method for constructing UPLC fingerprint of Callicarpa nudiflora medicinal material, and standard fingerprint

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Embodiment 1

[0035] 1. Instruments and medicines

[0036]A Waters ACQUITY UPLC H-Class ultra-high performance liquid chromatograph was used. There are 10 batches of naked flower purple pearl medicinal materials, naked flower purple pearl, big leaf purple pearl, sharp tail maple, pearl maple, and Du Honghua medicinal materials, all from Hainan Jiuzhitang Pharmaceutical Co., Ltd., approved by researcher Xie Zhaoming of the Institute of Traditional Chinese Medicine, Hunan Academy of Traditional Chinese Medicine Identified as genuine; Verbacoside reference substance (batch number 111530-201310), luteolin reference substance (batch number 111720-2014085), and forsythiaside B reference substance (batch number 111811-201102) were purchased from China National Institutes for Food and Drug Control, For content determination, caffeic acid reference substance (batch number 111720-2014085) was purchased from China National Institute for the Control of Pharmaceutical and Biological Products, and for co...

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Abstract

The invention provides a method for constructing the UPLC fingerprint of a Callicarpa nudiflora medicinal material, and a standard fingerprint of the Callicarpa nudiflora medicinal material, obtainedthrough the method. The method for constructing the UPLC fingerprint of the Callicarpa nudiflora medicinal material comprises the following steps: preparing a sample solution, and carrying out ultra performance liquid chromatography. The method has the characteristics of simplicity, easiness in realization of chromatography conditions, high precision, and goo stability and good reproducibility ofan analysis result; and compared with other test analysis methods in the prior art, the method in the invention has the advantages of shortening of the online analysis time and saving of the materialcost and the time cost.

Description

technical field [0001] The invention relates to the technical field of drug analysis, in particular to a method for constructing an ultra-high performance liquid chromatography (UPLC) fingerprint of a medicinal material of Auranthus nudica and a standard fingerprint thereof. Background technique [0002] Callicarpa nudiflora Hook.etAm. is the dry leaves and leafy shoots of Callicarpa L. in the Verbenaceae (Varbenaceae). In the Li area of ​​Hainan, it is also called Li medicine. Zizhu nudiflora nature and flavor are bitter, slightly pungent, flat. Return spleen, stomach, Liver Channel. It has the effect of dispelling blood stasis to stop bleeding, detoxify and reduce swelling. It is mainly used to treat epistaxis, hemoptysis, hematemesis, blood in stool, bruises, traumatic bleeding, water and fire burns, sores and ulcers. [0003] Nowadays, the application of nudibranch base sources in the market is chaotic, and the phenomenon of the same substance with different names and...

Claims

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Application Information

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IPC IPC(8): G01N30/02
CPCG01N30/02
Inventor 宋潇黄胜谷陟欣邓芸叶惠煊周良
Owner HAINAN JIUZHITANG PHARMACY
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