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A kind of airtight rat breathing mask

A breathing mask, sealing type technology, applied in medical science, veterinary instruments, etc., can solve problems such as photoacoustic and thermoacoustic image quality deterioration

Active Publication Date: 2020-10-23
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, when performing photoacoustic and thermoacoustic imaging, the scanning part of the rat needs to be completely immersed in water to be detected by the ultrasonic probe. When scanning the brain of a rat, in order to ensure that the rat can breathe, the rat can only be placed Outside the water, the signal detection is done through the thin film and ultrasonic coupling agent, and the thin film and ultrasonic coupling agent will refract, scatter and absorb laser light, microwave and ultrasonic waves, which will deteriorate the quality of the obtained photoacoustic and thermoacoustic images

Method used

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  • A kind of airtight rat breathing mask
  • A kind of airtight rat breathing mask
  • A kind of airtight rat breathing mask

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Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0028] 1. Anesthesia: 3% sodium pentobarbital (40-50 mg / kg) was injected intraperitoneally or the rat was placed in a 4% concentration isoflurane induction box for gas induction anesthesia.

[0029]2. Hair removal: If the imaging technology used needs to remove part of the hair (such as: photoacoustic, thermoacoustic and ultrasonic imaging), it is necessary to remove the long hair with a special shaver for small animals in the designated area, and then use depilatory cream to remove it. Short and fluffy. (If it is necessary to ensure 100% air tightness, it is necessary to remove the hair in the contact area between the face of the rat and the special-shaped silicone sealing ring with a shaver, so as to ensure that the special-shaped silicone sealing ring 2 is in contact with the skin of the rat's face).

[0030] 2. Connect the gear bar 3 and the exhaust gas recovery tank (such as activated carbon recovery tank) with a silicone tube to ensure that the experimenter will not come...

specific Embodiment approach 2

[0036] With the help of the invention, a new living rat imaging method based on photoacoustic and thermoacoustic technology can be realized. Compared with the specific implementation mode one, the specific implementation mode two has differences in the method of conducting research on point 5, and the specific implementation mode is:

[0037] 1. The rat wearing the present invention can be installed on the corresponding rat holder through the circular positioning groove 7 of the present invention.

[0038] 2. After adjusting the posture of the rat through the rat fixer, put the whole fixer directly into the coupling medium for photoacoustic and thermoacoustic imaging scanning, which can satisfy the requirements of photoacoustic and thermoacoustic imaging experiments after the rat dives into the water. Experimental requirements to ensure its free breathing.

[0039] Compared with the existing photoacoustic and thermoacoustic methods that only have thin films and ultrasonic cou...

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Abstract

The invention discloses a sealed type rat breathing mask, relates to an animal experiment device, in particular to a rat breathing mask. The invention aims to solve the problems of effectively fixing the rat's head and preventing gas leakage inside the mask. The invention is composed of a special-shaped bowl-shaped shell, a special-shaped silicone sealing ring, a gear rod, a silicone ring and a tightening ring. The special-shaped bowl-shaped shell combined with the silicone sealing ring makes the mask fit the rat's face. The tooth rod connects the rat and the breathing mask and also serves as the air outlet channel of the mask. The tightening ring can effectively fix the tooth rod and complete the sealing of the air outlet. . The good airtightness of the invention can not only effectively prevent the experimenters from being exposed to dangerous gases and prevent the outside gas (liquid) from entering the mask, but also can satisfy the requirements of photoacoustic, thermoacoustic imaging and other experiments and ensure the free breathing of rats after they dive into the water. experimental needs.

Description

technical field [0001] The invention relates to an animal experiment device, in particular to a rat breathing mask. Background technique [0002] In medical and life science research, respiratory masks, as an important device in rat experiments, have been widely used in experiments such as inhalation anesthesia, inhalation drug delivery, and exposure to oropharyngeal smoke. Existing rat breathing masks are mainly developed for brain stereotaxic instruments, MRI and other equipment. Usually, the rat's teeth are placed on the rack, and the conical (or cylindrical) suction mask is moved backward until it clings to the mouth. Go around the rat's nose or press down the rat's nose by moving the fixed block down to fix the rat's head. However, the rat's head is not completely conical, and the animal's face cannot fit the mask completely. In order to prevent harmful leakage of anesthetic gas, a recovery mask is generally designed outside the conical inhalation mask to cooperate wit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61D7/04
CPCA61D7/04
Inventor 赵渊蒋华北葛绍理赵芮
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA