Pharmaceutical composition capable of activating blood circulation to dissipate blood stasis, and preparation method thereof

Abstract

The invention discloses a pharmaceutical composition capable of activating blood circulation to dissipate blood stasis, and a preparation method thereof. The pharmaceutical composition comprises the following raw materials by weight: 4-8 parts of the bio-transformed mycelium of earthworms, 4-8 parts of Radix Astragali, 2-4 parts of red sage roots, 2-4 parts of Rhizoma Chuanxiong and 2-4 parts of safflower. The preparation method comprises the following steps: weighing the bio-transformed mycelium of earthworms, adding water, carrying out vacuumized extraction at 40-60 DEG C, and subjecting obtained extract to filtering, concentrating, freeze drying and low-temperature crushing so as to obtain the lyophilized powder of the bio-transformed mycelium of earthworms; weighing Radix Astragali, red sage roots, Rhizoma Chuanxiong and safflower, adding water, carrying out vacuumized extraction at 40-60 DEG C, and then successively carrying out vacuumized concentration and spray-drying so as to obtain extract powder; and mixing the lyophilized powder of the bio-transformed mycelium of earthworms with the extract powder. The prepared pharmaceutical composition has substantial effect on activating blood circulation to dissipate blood stasis, shows higher activity, and can resist myocardial ischemia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicinal composition for promoting blood circulation and removing blood stasis and a preparation method thereof. Background technique [0002] Stroke is the name of a disease in traditional Chinese medicine, and it is also the collective name and common name for acute cerebrovascular diseases. This disease is a group of diseases whose main clinical manifestations are cerebral ischemia and hemorrhagic injury symptoms. , has a very high mortality rate and disability rate, and is mainly divided into two categories: hemorrhagic stroke (cerebral hemorrhage or subarachnoid hemorrhage) and ischemic stroke (cerebral infarction, cerebral thrombosis). The early mortality rate of hemorrhagic stroke is very high. About half of the patients died within a few days of the onset. Although the survivors have been actively treated, most of them still have seque...

AI Technical Summary

Problems solved by technology

For example, the patent application number CN201810218625.3 discloses a traditional Chinese medicine composition for nourishing qi and activating blood circulation and its preparation method. The effect is not good, and there is a problem of side effects. The composition of this invention is composed of Panax notoginseng, pueraria lobata, Chuanxiong, hawthorn, safflower, earthworm, salvia miltiorrhiza, red peony root, angelica, motherwort and astragalus. The above drugs are pulverized and sieved, Decoct the extract, dry and pulverize, and press into tablets.

In this invention, due to the high temperature in the process of processing and storage, active substances such as thrombin will be greatly lost, reducing its efficacy, and the Chinese medicine composition obtained by the preparation method in this invention contains more impurities , the efficacy of the drug will be reduced, and some side effects will occur; all the raw materials are extracted together, and at higher temperatures (usually above 60°C), the raw materials will affect each other, and some of the heat-labile activities The substance is destroyed or lost, and the content of impurities increases, and the side effects are large

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