Ent-isopimarane diterpene and preparation method and application thereof

Abstract

The invention discloses an ent-isopimarane diterpene and a preparation method and an application thereof. The preparation method includes the following steps: drying and pulverizing roots of Euphorbiahylonoma; extracting by methanol, and then separately extracting by ethyl acetate and n-butanol; and separating a part of the ethyl acetate by utilizing a macroporous resin column, a silica gel column, a reversed phase chromatography column and a semi-preparative reversed phase high-performance liquid chromatography to prepare the compound. The compound has obvious phytotoxic activity on the roots and leaf sheaths of bluegrass seedlings; and it is found that the inhibition rate of the compound against bluegrass is higher than that of positive control glyphosate through experiments, but thereis no obvious inhibition effect on the roots and the leaf sheaths of lettuce, and so, the compound can be used as a selective herbicide in vegetable fields. The ent-isopimarane diterpene is a yellow oil substance, which has a chemical structural formula as shown in a formula (I).

Description

technical field [0001] The invention belongs to the field of natural product chemistry, and in particular relates to an en-isopirazane diterpene and its preparation method and application. Background technique [0002] Weeds refer to all plants that grow unfavorable to human activities or harmful to production sites. They survive long-term adaptation to local crops, cultivation, farming, soil, climate and other ecological and social conditions. According to the Food and Agriculture Organization of the United Nations, there are about 50,000 species of weeds in the world, 8,000 of which are farmland weeds, 76 of which are relatively serious, and 18 of which are extremely serious, known as vicious weeds. The root system of weeds is generally more developed, and the ability to absorb water and fertilizer is extremely strong, and they will compete with crops for water and fertilizer. Moreover, the growth speed of weeds is very fast, which can preemptively invade the space above ...

AI Technical Summary

Problems solved by technology

Because weeds directly or indirectly affect the growth of crops in terms of soil nutrients, water, growth space, and the spread of diseases and insect pests, they will eventually lead to a decline in crop yield and quality, and the losses caused cannot be ignored

And weed control will spend a lot of manpower, material resources and capital, which makes the production cost greatly increased

Images