A kind of enantiopimarane type diterpene and its preparation method and application

Abstract

The invention discloses an enantiopimarane-type diterpene and a preparation method and application thereof. In the present invention, after drying and pulverizing the root of spurge of Hubei, it is first extracted with methanol, then extracted with ethyl acetate and n-butanol respectively, and finally the ethyl acetate part is used in a macroporous resin column, a silica gel column, a reversed-phase chromatographic column and a The compound was isolated by semi-preparative reverse-phase high performance liquid chromatography. The compound has obvious phytotoxic activity on the roots and leaf sheaths of bluegrass seedlings, and it is found through experiments that its inhibitory rate on bluegrass is higher than that of the positive control glyphosate, but it has no obvious inhibition on the roots and leaf sheaths of lettuce Therefore, the compound can be used as a selective herbicide in vegetable fields. The enantiopimarane-type diterpene is a yellow oil, and its chemical structural formula is shown in formula (I):

Description

technical field [0001] The invention belongs to the field of natural product chemistry, and in particular relates to an enantiopimarane type diterpene and a preparation method and application thereof. Background technique [0002] Weeds refer to all plants that grow on the production site that are unfavorable to human activities or harmful to production sites. They survive long-term adaptation to local crops, cultivation, farming, soil, climate and other ecological and social conditions. According to the Food and Agriculture Organization of the United Nations, there are about 50,000 kinds of weeds in the world, of which 8,000 are farmland weeds, 76 of which are more serious and 18 are extremely harmful, which are called malignant weeds. The root system of weeds is generally more developed, and the ability to absorb water and fertilizer is extremely strong, and they will compete with crops for water and fertilizer. Moreover, weeds grow very fast, and they can preemptively oc...

AI Technical Summary

Problems solved by technology

Because weeds directly or indirectly affect the growth of crops in terms of soil nutrients, water, growth space, and the spread of diseases and insect pests, they will eventually lead to a decline in crop yield and quality, and the losses caused cannot be ignored

And weed control will spend a lot of manpower, material resources and capital, which makes the production cost greatly increased

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