Vigabatrin oral liquid preparation for children and preparation method thereof

Abstract

The invention belongs to the technical field of medicine, and discloses a vigabatrin oral liquid preparation for children and a preparation method thereof. Antiepileptic medicine of vigabatrin is usedas an active ingredient; proper auxiliary materials, such as sweetening agents, mucilage, aromatics and preservatives are added; liquid with clear and transparent appearance, good mouthfeel and highstability is prepared. The vigabatrin preparation is a solution type; the concentration is proper; the medication dosage can be precisely regulated; the taking is convenient; the absorption is fast; the effect taking speed is high; the clinic medication and family medication requirements can be met; the medicine can be easily accepted by children patients. The vigabatrin oral liquid preparation provided by the invention can sufficiently overcome the defects that the dosage of tablets and granules cannot be precisely regulated, and the medicine taking by children is difficult.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a vigabatrin oral liquid preparation for children and a preparation method thereof. Background technique [0002] Epilepsy is a common childhood disease that is prone to multiple occurrences, and it is a paroxysmal dysfunction of the central nervous system. The main pathological changes of epilepsy are sudden, repeated and short-term central nervous system dysfunction caused by excessive discharge of brain neurons, which has the characteristics of sudden, temporary, and repetitive. The clinical manifestations of the patient are sudden loss of consciousness, limb twitching, and mental And behavioral disorders. According to relevant domestic data survey statistics, epilepsy accounts for 0.8 to 1.5% of the population. The incidence of children is particularly high, and may affect the mental and development of children. The occurrence of epilepsy seriously endangers family ha...

AI Technical Summary

Problems solved by technology

[0008] For epilepsy patients, especially children, ordinary tablets have poor oral compliance, are difficult to adjust the dose, and have a slow onset of action; granules need to be prepared into solutions with warm water before use, and omissions in the preparation process will lead to The dosage is not easy to control, and the taste is not good without flavoring agents, which is not easy to be accepted by children

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