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Medical adhesive with efficient anti-inflammation and hemostasis functions

An efficient and functional technology, applied in the field of medical adhesives, can solve problems affecting the effect, application and side effects of medical adhesives

Active Publication Date: 2018-11-27
浙江派菲特新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The production of formaldehyde during the storage and use of cyanoacrylate medical adhesives has side effects on biological tissues, and with the increase of formaldehyde concentration, the damage to organisms increases, which seriously affects the effect and application of medical adhesives

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] A medical glue with high-efficiency anti-inflammatory and hemostatic functions, comprising the following components in parts by weight: 20 parts of n-octyl α-cyanoacrylate, 25 parts of isooctyl α-cyanoacrylate, 2 parts of polyvinyl acetate, 12 parts of high-efficiency anti-inflammatory components, 13 parts of high-efficiency hemostatic components, 3 parts of cell activator MG-60, 8 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, and 150 parts of compound anti-inflammatory fruit oil components 200 parts of sterile water; the high-efficiency anti-inflammatory components are calculated according to the weight fraction, including 2 parts of abalone anti-inflammatory peptide, 3 parts of chitin of Yunnan pine caterpillar pupae, 6 parts of Scrophulariaceae polysaccharide, and 5 parts of Xingguan fruit extract; The hemostatic components are calculated according to the weight fraction, including 5 parts of Burnet Burnet extract, 3 parts of Xinjiang C...

Embodiment 2

[0058] A medical glue with high-efficiency anti-inflammatory and hemostatic functions, comprising the following components in parts by weight: 22 parts of n-octyl α-cyanoacrylate, 28 parts of isooctyl α-cyanoacrylate, 4 parts of polyvinyl acetate, 16 parts of high-efficiency anti-inflammatory components, 18 parts of high-efficiency hemostatic components, 4 parts of cell activator MG-60, 9 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, and 180 parts of compound anti-inflammatory fruit oil components 200 parts of sterile water; the high-efficiency anti-inflammatory components are calculated according to the weight fraction, including 2 parts of abalone anti-inflammatory peptide, 3 parts of chitin of Yunnan pine caterpillar pupae, 6 parts of Scrophulariaceae polysaccharide, and 5 parts of Xingguan fruit extract; The hemostatic components are calculated according to the weight fraction, including 5 parts of Burnet Burnet extract, 3 parts of Xinjiang C...

Embodiment 3

[0061] A medical glue with high-efficiency anti-inflammatory and hemostatic functions, comprising the following components in parts by weight: 24 parts of n-octyl α-cyanoacrylate, 32 parts of isooctyl α-cyanoacrylate, 5 parts of polyvinyl acetate, 18 parts of high-efficiency anti-inflammatory components, 20 parts of high-efficiency hemostatic components, 5 parts of cell activator MG-60, 10 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, and 200 parts of compound anti-inflammatory fruit oil components 200 parts of sterile water; the high-efficiency anti-inflammatory components are calculated according to the weight fraction, including 2 parts of abalone anti-inflammatory peptide, 3 parts of chitin of Yunnan pine caterpillar pupae, 6 parts of Scrophulariaceae polysaccharide, and 5 parts of Xingguan fruit extract; The hemostatic components are calculated according to the weight fraction, including 5 parts of Burnet Burnet extract, 3 parts of Xinjiang ...

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Abstract

The invention discloses a medical adhesive with efficient anti-inflammation and hemostasis functions. The medical adhesive is characterized by comprising, by weight, 20-25 parts of alpha-N-octyl cyanoacrylate, 25-35 parts of alpha-isooctyl cyanoacrylate, 2-6 parts of polyvinyl acetate, 12-20 parts of efficient anti-inflammation components, 13-23 parts of efficient hemostasis components, 3-6 partsof cell activators MG-60, 8-10 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizers, 150-220 parts of compound anti-inflammatory fruit oil components and 200 parts of sterilewater. The medical adhesive particularly selects various extracts with the anti-inflammation and hemostasis functions, two efficient anti-inflammation components and one efficient hemostasis componentare added, so that overall anti-inflammation and hemostasis effects are improved, and the medical adhesive is high in bonding strength and short in hemostasis time and meets application requirementsof clinical medical adhesives.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a medical glue with high-efficiency anti-inflammatory and hemostatic functions. Background technique [0002] With the advancement of medicine, the clinical requirements for the effect of surgical techniques and auxiliary materials are getting higher and higher. The requirements of modern medicine are to minimize the pain of the patient and to guarantee the life of the patient to the maximum extent, so rapid hemostasis and anti-inflammation during the operation are particularly important. Medical adhesive is a branch of medical polymer. It takes biological tissue as the bonding object. Most of the tissues and organs of the human body can be replaced by adhesive technology during the treatment process, without anesthesia; wound healing Then it will fall off automatically. Compared with traditional methods, the use of medical adhesives can effectively shorte...

Claims

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Application Information

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IPC IPC(8): A61L24/00A61L24/06
CPCA61L24/0005A61L24/0015A61L24/06A61L2300/236A61L2300/30A61L2300/404A61L2300/41A61L2300/418A61L2400/04C08L29/04C08L33/18
Inventor 林闪光叶善明李程辉应磊
Owner 浙江派菲特新材料科技有限公司
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